Navigation Links
Novel protein complex enables survival in hostile environment

this enzyme originated from a gene fusion event."

"From the affinities and reaction rates it is clear that the enzyme will sense even a minute amount of sulfite and will neutralize even a large amount of sulfite very quickly. These properties suited the need of the ancient methanogens when oxygen appeared on earth," Mukhopadhyay said. "But, why did the organism have this enzyme in the first place?"

A clue comes from published works by Robert White, professor of biochemistry at Virginia Tech, who studies how metabolic systems evolved and collaborates with Mukhopadhyay. "It is possible that M. jannaschii had this enzyme for cofactor biosynthesis and having it in advance gave the organism a selective advantage when oxygen, and consequently sulfite, appeared," Mukhopadhyay said. "Since we now know that methanogens had a way to handle sulfite toxicity, we could hypothesize that the rest of the sulfate reduction pathway once existed in these organisms."

Johnson and Mukhopadhyay have already seen some remnants of this system in M. jannaschii. Thus, they say, it is possible that methanogenesis and sulfate reduction could have originated in the same organism after all, and, in the course of time, a loss of the sulfite reductase gene gave rise to a sulfite-sensitive methanogen. Similarly the loss of certain key genes gave rise to the archaea that reduces sulfate, but do not make methane. "But it is equally possible that the sulfite reduction system was developed in another organism and the methanogens acquired the sulfite reduction gene via horizontal transfer from that entity," Mukhopadhyay said.

Rolf Thauer, professor and head of the Department of Biochemistry at the Max Planck Institute for Terrestrial Microbiology in Marburg, Germany, and a noted authority on anaerobic microorganisms, commented: "The finding of a novel sulfite reductase in a methanogenic archaeon is an important discovery. It may prove to be directly relevant to the a
'"/>

Source:Virginia Tech


Page: 1 2 3 4 5

Related biology news :

1. Novel Asthma Study Shows Multiple Genetic Input Required; Single-gene Solution Shot Down
2. Novel technology detects human DNA mutations
3. Novel antiviral technology inhibits RSV infection in mice
4. Novel Enzyme Shows Potential As An Anti-HIV Target
5. Novel Therapy Tested in Mice Could Chase Away Cat Allergies
6. Discovery Could Lead To Novel Approaches In HIV Treatment
7. Novel ultrafast laser detection of cancer cells also may improve understanding of stem cells
8. Research Using Mouse Models Reveals A Novel Key Player In The Initiation Of Colon Cancer
9. Novel gene-silencing nanoparticles shown to inhibit Ewings sarcoma
10. Novel live reporting system to track cells
11. Field of beams - Novel system uses polarized light pulses to reveal crop health
Post Your Comments:
*Name:
*Comment:
*Email:
TAG: Novel protein complex enables survival hostile environment

(Date:7/11/2014)... the National Institute of Standards and Technology (NIST) ... more effectively, they often prove that necessity is ... case recently for M. Lorna De Leoz and ... specialization of glycomics. Glycomics is the study of ... are attached to proteins and lipids and influence ...
(Date:7/11/2014)... Researchers from Salk Institute for Biological Studies, BGI, ... the safety and reliability of the existing targeted ... method, TALEN-HDAdV, which could significantly increased gene-correction efficiency ... study published online in Cell Stell Cell ... cell-based gene therapy. , The combination of stem ...
(Date:7/11/2014)... the Max Planck Institute for Medical Research in Heidelberg, ... photosynthesis, the process by which the Earth first gained ... which is therefore crucial for all higher forms of ... first direct visualization of a crucial event in the ... protein complex, photosystem II, splits water into hydrogen and ...
Breaking Biology News(10 mins):A new genome editing method brings the possibility of gene therapies closer to reality 2A first direct glimpse of photosynthesis in action 2
... major world religions can play a key role in preserving ... the Swedish University of Agricultural Sciences (SLU), among others, indicates ... a change, they would be ideally positioned to do so. ... distributed around the world and how they overlap areas that ...
... researchers today released seven technical reports that together ... fracturing, the controversial natural gas and oil extraction ... totaling nearly 200 pages, examine seven critical topics ... Michigan, with an emphasis on high-volume methods: technology, ...
... wastewater managers are missing substantial opportunities to save energy ... 4) by Water in the West, a research center ... A Literature Review," also identifies the amount of water ... and coal, and to generate electricity. , The report ...
Cached Biology News:Religious leaders can be key to biological diversity 2U-M technical reports examine hydraulic fracturing in Michigan 2U-M technical reports examine hydraulic fracturing in Michigan 3U-M technical reports examine hydraulic fracturing in Michigan 4U-M technical reports examine hydraulic fracturing in Michigan 5U-M technical reports examine hydraulic fracturing in Michigan 6U-M technical reports examine hydraulic fracturing in Michigan 7Report reveals missed opportunities to save water and energy 2
(Date:7/10/2014)... Francisco, CA (PRWEB) July 10, 2014 ... family closer together. The Archer Family purchased a ... contained within DNA, but ended up with a lifetime ... discoveries contained within the family members’ DNA genuinely brought ... had decided to search deeper into genetic history and ...
(Date:7/10/2014)... , July 10, 2014  Franciscan St. ... of capnography for respiratory monitoring outside the ... healthcare leaders in embracing state-of-the-art patient safety ... patients are breathing and can alert medical ... measuring the amount of carbon dioxide the ...
(Date:7/10/2014)... OAKS, Calif., July 10, 2014   Ceres, Inc ... and seed company, announced today financial results for the ... update on its business. Ceres reported that ... in product performance this growing season in Brazil, which ... affected the company,s sorghum evaluation areas for part of ...
(Date:7/10/2014)... psychiatric disorders has been extremely challenging because there are ... insufficient to cause disease. Now investigators reporting in the ... Cell Stem Cell describe a strategy that may ... other risk factors or environmental exposures to affect the ... genetic variant that may predispose individuals to schizophrenia. ...
Breaking Biology Technology:Ancestry DNA Test Reveals a Controversial and Undiscovered Family History 2Ancestry DNA Test Reveals a Controversial and Undiscovered Family History 3Ancestry DNA Test Reveals a Controversial and Undiscovered Family History 4Ancestry DNA Test Reveals a Controversial and Undiscovered Family History 5Franciscan St. Anthony Health-Crown Point Underscores Patient Safety Commitment Through Expanded Use of Capnography 2Ceres Announces Fiscal Third Quarter 2014 Financial Results 2Ceres Announces Fiscal Third Quarter 2014 Financial Results 3Ceres Announces Fiscal Third Quarter 2014 Financial Results 4Ceres Announces Fiscal Third Quarter 2014 Financial Results 5Ceres Announces Fiscal Third Quarter 2014 Financial Results 6Ceres Announces Fiscal Third Quarter 2014 Financial Results 7Ceres Announces Fiscal Third Quarter 2014 Financial Results 8Ceres Announces Fiscal Third Quarter 2014 Financial Results 9New strategy could uncover genes at the root of psychiatric illnesses 2
... 2010 -- Tomorrow,s television and computer screens could be ... a process developed by a team of researchers from ... Laboratory. The synthesis of a conjugated organic polymer--widely ... diodes, televisions and solar cells--could mean more efficient, cheaper ...
... , SAN DIEGO , July 19 "Amira ... with GlaxoSmithKline, has achieved two clinical development milestones." , ... These milestones are related to the successful progression of the program ... inhibitor in patients suffering from asthma.   , ...
... July 16 Talecris Biotherapeutics Holdings Corp. (Nasdaq: TLCR ) will issue ... 2010 . Due to the pending merger with Grifols, S.A., Talecris will not be ... , , ... , , , ...
Cached Biology Technology:Polymer synthesis could aid future electronics 2Amira Pharmaceuticals Hits Two Development Milestones Related to FLAP Inhibitor Program 2