Navigation Links
Novel protein complex enables survival in hostile environment

lfite. "Early earth had a lot of sulfide but no oxygen until about 2.7 billion years ago. Then, the reaction of the small amounts of oxygen with sulfide would have produced an incomplete oxidation product ?sulfite," he said. "Methanogens present during the oxygenation of earth had to face this sulfite."

But Johnson and Mukhopadhyay could not find any sign of such ability in the DNA sequence data for methanogens. "It was clear that either the ancient sulfite detoxification has been lost or it is not recognizable because it is unlike any known system," Mukhopadhyay said.

The challenge of the latter possibility attracted the group to the topic. They decided to see if methanogens that live in an environment where the early earth conditions are preserved ?deep-sea hydrothermal vents ?still have the ancient detoxification system.

Inside a hydrothermal vent, sulfide-containing superheated water at 350 C (662 F) mixes with cold oxygen-containing water, creating cooler environments -- 48 to 94 C (118 to 200 F) -- where M. jannaschii can thrive. "This sulfide-oxygen mixture can also generate sulfite. Therefore, M. jannaschii experiences conditions that existed on early earth," Mukhopadhyay said.

He knew that Lacy Daniels, his mentor at the University of Iowa, and Negash Belay, a colleague during his graduate studies, had found sulfite assimilation ability in an organism closely related to M. jannaschii, but had not investigated how that organism handled the sulfite toxicity. Putting all these pieces of information together, Johnson and Mukhopadhyay hypothesized that M. jannaschii has a sulfite-reducing enzyme and began to search for this system.

Protein analysis of M. jannaschii from sulfite-free and sulfite-enhanced environments revealed that M. jannaschii tolerates sulfite and even uses it as a sulfur source by expressing an enzyme not seen previously. The enzyme, which is located on the cell membrane, converts toxic sulfite into
'"/>

Source:Virginia Tech


Page: 1 2 3 4 5

Related biology news :

1. Novel Asthma Study Shows Multiple Genetic Input Required; Single-gene Solution Shot Down
2. Novel technology detects human DNA mutations
3. Novel antiviral technology inhibits RSV infection in mice
4. Novel Enzyme Shows Potential As An Anti-HIV Target
5. Novel Therapy Tested in Mice Could Chase Away Cat Allergies
6. Discovery Could Lead To Novel Approaches In HIV Treatment
7. Novel ultrafast laser detection of cancer cells also may improve understanding of stem cells
8. Research Using Mouse Models Reveals A Novel Key Player In The Initiation Of Colon Cancer
9. Novel gene-silencing nanoparticles shown to inhibit Ewings sarcoma
10. Novel live reporting system to track cells
11. Field of beams - Novel system uses polarized light pulses to reveal crop health
Post Your Comments:
*Name:
*Comment:
*Email:
TAG: Novel protein complex enables survival hostile environment

(Date:7/31/2014)... ago, prestin was found to be a key gene responsible ... in the hair cells of the inner ear that contracts ... like an antique phonograph horn, amplify sound waves to make ... published in the advanced online edition of Molecular Biology ... prestin has also independently evolved to play a critical role ...
(Date:7/31/2014)... GAINESVILLE, Fla. --- By tracing nearly 3,000 genes ... moths, University of Florida scientists have created an ... to use large-scale, next-generation DNA sequencing. , ... more closely related to small moths than to ... how butterflies evolved. The study also found that ...
(Date:7/31/2014)... studied 100 twin pairs have identified a gene mutation that ... six hours of sleep per night. The genetic variant ... sleep deprivation. , Results show that a participant with p.Tyr362His ... average nightly sleep duration of only five hours, which was ... slept for about six hours and five minutes per night. ...
Breaking Biology News(10 mins):UF study advances 'DNA revolution,' tells butterflies' evolutionary history 2UF study advances 'DNA revolution,' tells butterflies' evolutionary history 3Study of twins discovers gene mutation linked to short sleep duration 2
... review article by researchers at Boston University School of ... high blood pressure, is the result of excess salt ... the arteries. Published online in the Journal of ... the sympathetic nervous system to produce adrenalin, causing artery ...
... today in PLoS ONE entitled, Zoonotic ... a collaborative study led by the U.S. Centers ... of retroviruses and herpesviruses in illegally imported wildlife ... John F. Kennedy International Airport, George Bush Intercontinental-Houston ...
... (UCSF) has signed an alliance with international pharmaceutical company ... in diabetes research and identify drug targets that could ... type 2 diabetes. The $3.1 million collaboration will ... understanding of the biology of beta cells insulin-producing ...
Cached Biology News:Boston University School of Medicine researchers clarify link between salt and hypertension 2Study establishes importance of tracking diseases associated with illegal wildlife trade 2Study establishes importance of tracking diseases associated with illegal wildlife trade 3UCSF, Sanofi collaborate to find new diabetes cures 2UCSF, Sanofi collaborate to find new diabetes cures 3
(Date:8/1/2014)... August 01, 2014 Once a decision ... cost? This webinar will discuss how to define your ... Join speakers Bob Allen, Senior Director of Facilities Integration ... Engineering at Fluor Industrial Services, and special guest Carrier ... Planning at Amgen, as they provide an examination of ...
(Date:8/1/2014)... Aug. 1, 2014 Glencoe Software, ... of "Data InPress" ( http://glencoesoftware.com/data-inpress.html ), a ... multidimensional image data into on-line publications.  The ... Video Injection Service. Photo - ... http://photos.prnewswire.com/prnh/20140731/132409 The DataViewer ...
(Date:7/31/2014)... “2014 Deep Research Report ... is a professional and in-depth research report ... Polyurethane Resin basic information, including its definition, ... industry overview. This research covers the international ... well as global industry analysis covering macroeconomic ...
(Date:7/31/2014)... not donor candidates for bone marrow transplantation. The immune ... prone to life-threatening infection and other maladies, and a ... reason why. , "We have found the cellular mechanism ... blood production over time in an old organism, and ... rejuvenation therapies," said Emmanuelle Passegu, PhD, a professor of ...
Breaking Biology Technology:Defining Low Cost in Your Solution for Future Facilities, New Webinar for Pharma, Biotech, Medical Device and Healthcare Companies, Hosted by Xtalks 2Glencoe Software Launches Data InPress 2Glencoe Software Launches Data InPress 3Polyurethane Resin Industry & Thermoplastic Polyurethane Market (China, Global) Analysis Now at DeepResearchReports.com 2Polyurethane Resin Industry & Thermoplastic Polyurethane Market (China, Global) Analysis Now at DeepResearchReports.com 3Polyurethane Resin Industry & Thermoplastic Polyurethane Market (China, Global) Analysis Now at DeepResearchReports.com 4Key to aging immune system is discovered 2
... practical use of visible light and zinc oxide nanorods ... by researchers at the Asian Institute of Technology (AIT). ... energy have been found to be effective in killing ... finding that has immense possibilities for affordable and environmentally ...
... of the Sciences Board of Trustees today elected Marvin ... R. Howard, CEO of Advanced Pharmacy Services, vice chairman. ... chair Dr. Delbert S. Payne, who was subsequently elected ... world-renowned leader in injectable manufacturing and delivery systems, Samson ...
... CHICO, Calif., May 12, 2011 Dan Neumeister, FACHE, ... healthcare management services firm, has been selected by Chase ... as interim chief executive officer (CEO) effective May 1, ... health center,s CEO Search Committee permanently fills the position. ...
Cached Biology Technology:Exposing ZnO nanorods to visible light removes microbes 2USciences Board of Trustees Elects Marvin Samson Chairman and Richard R. Howard Vice Chairman 2Regional Healthcare Management Firm Goes National 2
... Software reads and processes raw ... microarray data for analysis. ... one 2-year license for Feature ... , * one CD-ROM ...
... and SYBR Safe DNA Gel Stain combo offers these ... buying these same products separately ... bromide Eliminates risks to ... and RNA fragments from 100 bp to >30 kb. ...
Anti-WT-1 Liquid. In 10 μM PBS, 0.2 % BSA, pH 7.6. Recognizes the ~47-55 kDa Wilm's tumor protein in Wilm's tumor tissue. ...
... The economical ICS-90 uses continuous chemical ... to give you fast, accurate determinations of ... ranges. Easy to operate, quick to equilibrate, ... the compact ICS-90 helps you achieve maximum ...
Biology Products: