Navigation Links
Noise echoes in cell communications

Can't hear? Turn up the white noise, says a team of Rutgers-Camden professors who have produced a mathematical explanation for the benefits of noise. Their findings could lead to major improvements in hearing aid technology.

Dawei Hong, an assistant professor of computer science, Joseph Martin, a professor of biology, and William Saidel, an associate professor of biology, are working together to explain the biological benefits of noise through mathematics. Although the Rutgers-Camden team did study noise in the auditory system, "noise" can also refer to not just what we hear, but a randomness that is essential to all life.

"There is no life without noise; noise is the secret of life," suggests Martin, who points to the constant movement of particles under a microscope to illustrate this phenomena. Unlike a physics experiment that can produce the same result after various attempts, in biology, one particular experiment can yield a multitude of outcomes.

This randomness, however, isn't problematic, but a necessary function for survival. Until now, the role of randomness in sustaining life has been a great and unsolved problem. The collaborative research underway at Rutgers-Camden has led to new understanding of how living organisms might exploit randomness for important processes of sensory processing and cell to cell communication.

In terms of hearing, the Rutgers-Camden research team's mathematical theory improves previous knowledge by offering a single explanation of the properties of noise in hearing under different conditions. To develop the theory, Hong used a variation on the wavelet technique, which he says is responsible for clarifying the JPG image. The findings could have numerous applications ?most obviously in treating hearing loss by artificially increasing the amount of noise in the cochlea of the inner ear, perhaps by an implanted device.

Hong, Saidel and Martin applied this principle of noise to anothe r process called "quorum sensing" ?how bacteria signal one another to act collectively when causing an infection. The Rutgers-Camden research team used bacteria as a starting point for observing how noise enhances cell-to-cell communication. A full understanding of how this simple form of communication works might show how to disrupt it, and the resulting infection. The team will next apply their idea to the nervous system, where the cell's entire job is to communicate.

Published in top journals on theoretical biology, this collaborative research between biology and computer science faculty at Rutgers-Camden is part of a thrust to ultimately offer a doctoral program in computational and integrative biology on the Camden campus. "We talk about biological problems and apply mathematical principles," says Martin, who believes the development of the Systems Biology Institute in Camden, which will be managed by Rutgers-Camden, will further advance the systems biology discipline in South Jersey.


'"/>

Source:Rutgers, the State University of New Jersey


Related biology news :

1. Noise And Delays Explain Why Some Genes Oscillate In Activity
Post Your Comments:
*Name:
*Comment:
*Email:


(Date:4/26/2016)... LONDON , April 26, 2016 /PRNewswire/ ... Systems, a product subsidiary of Infosys (NYSE: ... partnership to integrate the Onegini mobile security platform ... http://photos.prnewswire.com/prnh/20151104/283829LOGO ) The integration ... security to access and transact across channels. Using ...
(Date:4/15/2016)... 15, 2016 Research and ... Biometrics Market 2016-2020,"  report to their offering.  , ... , ,The global gait biometrics market is expected ... the period 2016-2020. Gait analysis generates ... be used to compute factors that are not ...
(Date:3/31/2016)... -- Genomics firm Nabsys has completed a financial  restructuring under ... M.D., who returned to the company in October 2015. ... including Chief Technology Officer, John Oliver , Ph.D., ... Vice President of Software and Informatics, Michael Kaiser ... Bready served as CEO of Nabsys from 2005-2014 and ...
Breaking Biology News(10 mins):
(Date:6/23/2016)... 2016 /PRNewswire/ - FACIT has announced the creation ... biotechnology company, Propellon Therapeutics Inc. ("Propellon" or "the ... a portfolio of first-in-class WDR5 inhibitors for the ... WDR5 represent an exciting class of therapies, possessing ... for cancer patients. Substantial advances have been achieved ...
(Date:6/23/2016)... ... 2016 , ... Charm Sciences, Inc. is pleased to announce ... Research Institute approval 061601. , “This is another AOAC-RI approval of the Peel ... President of Regulatory and Industrial Affairs. “The Peel Plate methods perform comparably to ...
(Date:6/23/2016)... SAN FRANCISCO , June 23, 2016   ... it has secured $1 million in debt financing from ... to ramp up automation and to advance its drug ... for its new facility. "SVB has been ... goes beyond the services a traditional bank would provide," ...
(Date:6/23/2016)... ... 2016 , ... In a new case report published today in STEM CELLS ... developed lymphedema after being treated for breast cancer benefitted from an injection of stem ... with this debilitating, frequent side effect of cancer treatment. , Lymphedema refers ...
Breaking Biology Technology: