POWER Phase II TMC114 dosing trials
Over 24 weeks in the combined TMC114 trials, almost double the proportion of patients who received FUZEON plus TMC114/r achieved a viral load below 50 copies/ml compared with patients not receiving FUZEON A remarkable 67% of the patients receiving FUZEON plus TMC114/r reached an undetectable viral load
TORO Phase III FUZEON trials
Over 24 weeks, double the proportion of patients who received FUZEON plus lopinavir/r achieved an undetectable viral load (<50 copies/ml) compared with patients not receiving FUZEON
Collectively the data from all six studies, in over 2,500 patients, establish a new paradigm in the management of triple class-experienced patients.
Why FUZEON is effective in face of HIV resistance
FUZEON is still the first and only anti-retroviral drug to work outside the human immune cell (CD4), blocking the HIV virus from entering. All other currently available HIV drugs fight the HIV virus once it has entered the cell. FUZEON's unique mode of action means that FUZEON has no cross-resistance with currently available drugs and that it is an effective treatment, in combination with other anti–HIV drugs, for patients facing resistance.
New combination improves quality of life
Spike, a 48 year old person living with HIV from London, whose blood levels of HIV reached undetectable within six months of taking FUZEON and boosted tipranavir and has remained undetectable ever since, explains "This new combination of treatments has really improved my quality of life. Getting back to undetectable and seeing my CD4 count increase from 20 to 268 has changed my outlook on life. I believe I can plan for the future, which I didn't even consider doing before starting this regimen. I have much more energy now than I had before, which is exhilarating since I have been held b