Navigation Links
Newer imaging techniques may lead to over-treatment

Newer imaging technologies allow physicians to visualize more of the arteries in the lungs, including detecting small blood clots not previously seen, but seeing more may have little impact on the patient's outcome, a new study suggests.

The study included 198 patients with suspected pulmonary embolism. About half of the patients (98) had a multidetector CT (MDCT) examination; 100 patients had a single-detector CT examination. The radiology examinations came back negative, and the patients did not undergo anticoagulant treatment.

MDCT is now more widely used to examine patients with suspected pulmonary embolism. It allows radiologists to see more of the arteries throughout the lungs, and to detect small clots in those arteries, said J. David Prologo, MD, chief radiology resident at University Hospitals of Cleveland and lead author of the study. However, "our study found no significant difference in the outcomes of patients ruled out for pulmonary embolism with MDCT vs. single-detector CT," he said. "It is possible that we missed small clots in the patients that had a single-detector CT examination, but at three and six months, the outcomes were similar," he said.

Seeing more can have drawbacks as well, Dr. Prologo said. "If we see the small clots, we're more likely to treat them; and there are risks to anticoagulant therapy," he said. In fact, "a recent study found a 10 times higher risk of hemorrhagic stroke in patients receiving oral anticoagulant therapy when compared to the general population," Dr. Prologo said. It is imperative that "clinicians consider the risk-benefit ratio of therapy in patients with previously undetectable small clots in the peripheral pulmonary vasculature," he added.

Dr. Prologo recommends a large-scale prospective randomized study to determine if patients with small clots need to undergo anticoagulation treatment. "Today a great many more patients are being evaluated for pulmonary emboli with scanners that can detect very small clots. This is likely to result in the discovery of many more patients with small clots who probably would not have been treated in the past and may have done fine. Improved technology is forcing us to face new clinical questions such as whether or not every small clot diagnosed with CT warrants the risks of treatment," he said.


'"/>

Source:American Roentgen Ray Society


Related biology news :

1. New imaging method gives early indication if brain cancer therapy is effective, U-M study shows
2. Duke engineers develop new 3-D cardiac imaging probe
3. Confocal imaging promises early detection of skin cancer
4. Researchers use 3-D imaging system to unveil swimming behavior of microscopic plankton
5. Microscopic brain imaging in the palm of your hand
6. New imaging technology shown to detect pancreatic inflammation in type 1 diabetes
7. Purdues gold nanorods brighten future for medical imaging
8. PET imaging reveals the immune system at work
9. New technique puts brain-imaging research on its head
10. T-rays: New imaging technology spotlighted by American Chemical Society
11. UCLA imaging study of children with autism finds broken mirror neuron system
Post Your Comments:
*Name:
*Comment:
*Email:


(Date:4/13/2017)... , April 13, 2017 According to a ... Identity Authentication, Identity Analytics, Identity Administration, and Authorization), Service, Authentication Type, Deployment ... the IAM Market is expected to grow from USD 14.30 Billion in ... Rate (CAGR) of 17.3%. ... MarketsandMarkets Logo ...
(Date:4/6/2017)... Forecasts by Product Type (EAC), ... End-Use (Transportation & Logistics, Government & Public Sector, Utilities ... Generation Facility, Nuclear Power), Industrial, Retail, Business Organisation (BFSI), ... you looking for a definitive report on the $27.9bn ... ...
(Date:4/3/2017)... 3, 2017  Data captured by IsoCode, ... detected a statistically significant association between the ... treatment and objective response of cancer patients ... predict whether cancer patients will respond to ... well as to improve both pre-infusion potency testing ...
Breaking Biology News(10 mins):
(Date:10/12/2017)... FL (PRWEB) , ... October ... ... (RPS®) today announces publication of a United States multicenter, prospective clinical study ... use, disposable, point-of-care diagnostic test capable of identifying clinically significant acute bacterial ...
(Date:10/11/2017)... ... October 11, 2017 , ... At ... Purple announced Dr. Suneel I. Sheikh, the co-founder, CEO and chief research scientist ... has been selected for membership in ARCS Alumni Hall of Fame . ...
(Date:10/11/2017)... ... October 11, 2017 , ... Proscia Inc ., ... a Webinar titled, “Pathology is going digital. Is your lab ready?” with Dr. ... best practices and how Proscia improves lab economics and realizes an increase in ...
(Date:10/11/2017)... ... October 11, 2017 , ... A new study ... in frozen and fresh in vitro fertilization (IVF) transfer cycles. The ... IVF success. , After comparing the results from the fresh and frozen transfer ...
Breaking Biology Technology: