Navigation Links
Newborn neurons like to hang with the 'in' crowd

Like any new kid on the block that tries to fit in, newborn brain cells need to find their place within the existing network of neurons. The newcomers jump right into the fray and preferentially reach out to mature brain cells that are already well connected within the established circuitry, report scientists at the Salk Institute for Biological Studies in the online edition of Nature Neuroscience.

At first, they gingerly sniff out pre-existing connections between brain cells but as the new neurons mature over time they get emboldened and muscle out the old guys. "Adding new neurons could be a very problematic process if newborn cells would make connections all over the place," explains Fred H. Gage, Ph.D., a professor in the Gene Expression Laboratory and the Vi and John Adler Chair for Research on Age-Related Neurodegenerative Diseases. "But if they are only replacing already existing connections there is less chance of error," he adds.

Neurons make contact via specialized structures called synapses. As a signal traveling along a nerve branch arrives at the pre-synaptic area, it releases a chemical signal. The signaling molecules travel across the synapse and induce a signal on the neighboring, receiving nerve fiber or dendrite. A typical neuron sports about 7,000 synapses through which it stays in touch with roughly 1,000 other cells. But just how young neurons make their presence known and hook up with already well-connected elders has been unclear.

"If you have hopes that one day neuronal stem cells can replace damaged neurons in neurodegenerative diseases such as Alzheimer's or Parkinson's disease you have to ensure that these cells make proper connections, form functional synapses and integrate into the rest of the brain," says postdoctoral fellow Nicolas Toni, Ph.D., who headed the current study.

To figure out how the newcomers do it, the Salk researchers injected a virus carrying the gene for green fluorescent protein
'"/>

Source:Salk Institute


Page: 1 2 3

Related biology news :

1. Opiates Better Than Sedatives For Treating Newborns In Withdrawal
2. Newborn screening can cause unnecessary parental stress
3. Newborn brains grow vision and movement regions first
4. First real-time view of developing neurons reveals surprises, say Stanford researchers
5. One gene links newborn neurons with those that die in diseases such as Alzheimers
6. Researchers make surprise discovery that some neurons can transmit three signals at once
7. Speak up: Louder neurons form more connections
8. Eating, body weight regulated by specific neurons
9. New neurons take baby steps in the adult brain
10. Algal protein in worm neurons allows remote control of behavior by light
11. Picking apart how neurons learn
Post Your Comments:
*Name:
*Comment:
*Email:
TAG: Newborn neurons like hang with the crowd

(Date:11/21/2014)... NEW YORK , Nov. 19, 2014  Earlier ... Board at New York College, and one of the ... for biosensor signals that are transmitted from Smartphones to ... there were Smartphones and has one of the earliest ... are discussing its usage in the military, child care, ...
(Date:11/18/2014)... , Nov. 18, 2014  The Secure ... Industry Association today jointly announce the formation of ... release of its Identity and Biometric Entry ... The Framework received official support from BORDERPOL, the ... to improve and provide expertise regarding border security, ...
(Date:11/15/2014)... YORK , Nov. 13, 2014  While we may ... technology Doctor McCoy used in "Star Trek" to gain instant ... tools designed to work with smartphones and tablets for monitoring ... of the healthcare world. This may seem a tad Orwellian ... ready to adopt some of these technological opportunities into their ...
Breaking Biology News(10 mins):Patented Biosensor Wearable Technology Provides a More Civilized Method of Quarantine 2Patented Biosensor Wearable Technology Provides a More Civilized Method of Quarantine 3Patented Biosensor Wearable Technology Provides a More Civilized Method of Quarantine 4Identity Management, Document Authentication and Biometric Companies Form "The Airport Entry and Exit Working Group", Releasing the Framework to Help Guide the Department of Homeland Security and Congress Towards Solutions 2Identity Management, Document Authentication and Biometric Companies Form "The Airport Entry and Exit Working Group", Releasing the Framework to Help Guide the Department of Homeland Security and Congress Towards Solutions 3Americans May Be Ready for a Brave New World of Healthcare 2Americans May Be Ready for a Brave New World of Healthcare 3Americans May Be Ready for a Brave New World of Healthcare 4
... 3 issue of Nature, Johns Hopkins researchers report that ... come together to turn the liver into a sugar-producing ... of sugar is a damaging problem in people with ... future drugs to fight the disease, the researchers say. ...
... Mayo Clinic researchers and conducted by the North Central Cancer ... for an incurable form of recurrent brain cancer slowed tumor ... who tried it. The same research team also developed a ... to this treatment. , Mayo researchers will present these findings ...
... by camouflage in the same way that humans are deceived, ... idea that bold contrasting colours help to break-up the body's ... as the First World War. And in biology this idea ... insects such as moths conceal themselves from predators, shaping the ...
Cached Biology News:Computational verification of protein-protein interactions by orthologous co-expression 2Computational verification of protein-protein interactions by orthologous co-expression 3'Smart drug' targets deadly brain cancer 2'Smart drug' targets deadly brain cancer 3
(Date:11/26/2014)... Bioscience, Inc. (NASDAQ: ROKA ), a molecular diagnostics ... of foodborne pathogens, today announced that Paul G. Thomas ... Annual Healthcare Conference on December 2, 2014 at 4:30pm ET. ... in New York, NY . ... operations, strategies and prospects may be discussed. To listen to ...
(Date:11/24/2014)...   First published articles now ... Elsevier , a world-leading provider of scientific, technical and medical ... of the latest title in the Current Opinion journal ... . Current Opinion in ... to keep up-to-date with the expanding volume of information published ...
(Date:11/24/2014)... November 24, 2014 The new ... from METTLER TOLEDO demonstrates how to reduce the ... analytics and sample panel design can be complicated, ... and protect against corrosion and deposition. Dedicated single ... significant amount of panel space. Additionally, installing and ...
(Date:11/22/2014)... 21, 2014 During his lifetime Richard ... need to surround himself with great people and take ... his friends often marveled at his extraordinarily courageous attitude ... life and -- even with his death impending—that’s how ... disease that would ultimately take his life. , Carrying ...
Breaking Biology Technology:Roka Bioscience to Present at the Piper Jaffray Healthcare Conference 2Elsevier Announces Launch of New Journal: Current Opinion in Food Science 2Elsevier Announces Launch of New Journal: Current Opinion in Food Science 3New Video Shows How to Simplify Cycle Chemistry Sample Panels to Save Time and Costs 2Sherry Sharp, Wife of CarMax Founder, Richard Sharp, Accepts Seat on Board of Cure Alzheimer’s Fund 2Sherry Sharp, Wife of CarMax Founder, Richard Sharp, Accepts Seat on Board of Cure Alzheimer’s Fund 3
... ... Spectrum Chemicals & Laboratory Products (Spectrum) announced the distribution launch ... productivity and lessen injuries due to repetitive hand crimping. ... engineered to improve throughput in laboratories performing chromatography, analytical testing, ...
... , , FRAZER, Pa., Aug. ... that it has completed its previously announced acquisition of all of ... As a result of the acquisition, Arana is now a ... and CEO, Frank Baldino Jr., Ph.D., said, "We are excited about ...
... BEIJING, Aug. 10 /PRNewswire-Asia-FirstCall/ -- Yongye International, Inc.,(OTC ... developer and,distributor of Shengmingsu branded plant and animal nutrient ... that the Company expanded,its research and development center in ... greenhouses and an open testing field. , ...
Cached Biology Technology:Spectrum Announces New Distribution of AC-Powered Tool for Crimping and Decapping of Laboratory Vials - The CRIMPenstein™ 2Cephalon Completes Acquisition of Arana Therapeutics 2Cephalon Completes Acquisition of Arana Therapeutics 3Yongye International Announces Expansion of Research and Development Center 2Yongye International Announces Expansion of Research and Development Center 3
... Immunogen: Synthetic peptide derived from the C ... protein This peptide sequence is downstream ... Zymed polyclonal Connexin 36 antibody Cat. No. ... 36. Reactivity: Mouse (positive control: mouse ...
...
...
...
Biology Products: