Navigation Links
New type of rejection blocker protects kidneys after transplant

ded anti-hypertensive medication compared to one-third of patients in the two belatacept groups.

Over the past 20 years, drugs like cyclosporine (a calcineurin inhibitor) and prednisone (a corticosteroid) have been highly successful in overcoming organ rejection. However, Vincenti said, advances have only been modest in terms of keeping the organ healthy over the course of years. Paradoxically, anti-rejection drugs like cyclosporine contribute to health problems including cardiovascular disease -- the leading cause of death among kidney transplant recipients.

"This trial indicates that belatacept should be able to protect transplanted organs from rejection without the toxicities associated with today's standard drugs," Vincenti said.

Since standard immunosuppressants damage the kidneys, the new class of drugs also promises to reduce the number of patients who need a re-transplant. "This is one of the exciting results of this study, considering that we have a critical shortage of organs for transplant," Vincenti said.

Kidney transplant is the preferred treatment for most people with end-stage kidney failure. The United Network for Organ Sharing reports that more than 16,000 Americans received a kidney transplant in 2004.


'"/>

Source:University of California - San Francisco


Page: 1 2 3 4

Related biology news :

1. Simple sea sponge helps scientists understand tissue rejection
2. Researchers identify genes associated with lung transplant rejection
3. Carnegie Mellon develops non-invasive technique to detect transplant rejection at cellular level
4. Combination therapy with a monocloncal antibody and a vaccine leads to tumor rejection
5. Proteins may predict lung transplant rejection
6. Survival of heart patients on beta-blockers varies greatly with genetic variation
7. Bound for destruction: Ubiquitination protects against improper Notch signaling
8. Experiments provide proof of how traveling in groups protects insects
9. Experiments provide proof of how traveling in groups protects insects
10. Substance protects resilient staph bacteria
11. Molecule that usually protects infection-fighting cells may cause plaque deposits inside arteries
Post Your Comments:
(Date:3/18/2010)... Florida engineering researchers have found they can ignite certain nanoparticles ... door to a wave of new technologies in health care, ... appears in this week,s advance online edition of Nature ... Brij Moudgil say they used lasers not much more intense ...
(Date:3/18/2010)... , Scientists report a protein made by a gene ... diseases plays a pivotal role in protecting the intestinal ... investigators led the research, which points to possible new ... disease associated with colon damage, resulting in abdominal pain, ...
(Date:3/18/2010)... from stressful environments, but they can be surprisingly flexible ... likely to become more common under current climate-change scenarios. ... that plants use to cope with stress at the ... Research Institute at the Earl S. Tupper Research and ...
Breaking Biology News(10 mins):Engineers: Weak laser can ignite nanoparticles, with exciting possibilities 2Engineers: Weak laser can ignite nanoparticles, with exciting possibilities 3Study details machinery of immune protection against inflammatory diseases like colitis 2Smithsonian hosts 2010 International CAM Workshop in Panama 2Insmed Announces Addition to the Russell 3000 28R 29 Index 12842 1Insmed Announces Addition to the Russell 3000 28R 29 Index 12842 2Summertime Sun Exposure Can Burn Acne Sufferers in More Ways than One 50370 1Summertime Sun Exposure Can Burn Acne Sufferers in More Ways than One 50370 2Summertime Sun Exposure Can Burn Acne Sufferers in More Ways than One 50370 3Virginia Mason Signs with Carefx to Implement Fusionfx Solution Suite 50369 1Virginia Mason Signs with Carefx to Implement Fusionfx Solution Suite 50369 2Virginia Mason Signs with Carefx to Implement Fusionfx Solution Suite 50369 3
... of Veterinary Medicine at the University of Pennsylvania, and formed ... by Dr Lluís Tort of the Universitat Autònoma de Barcelona, ... in fish as well as in amphibians are capable of ... The work has been published in Nature Immunology, the most ...
... horned beetles' wild protrusions has been a matter of ... mate selection, more likely. Even Charles Darwin once weighed ... some frustration -- the horns were merely ornamental. ... the Nov. 2006 issue of Evolution, Indiana University Bloomington ...
... of the National Institutes of Health (NIH), today announced ... $13 million to speed the development of innovative sequencing ... expand the use of genomics in medical research and ... over the last several years to develop faster and ...
Other Biology News:Discovery in the evolution of the immune system absorbing cells 2Vanishing beetle horns have surprise function 2Vanishing beetle horns have surprise function 3NHGRI aims to make DNA sequencing faster, more cost effective 2NHGRI aims to make DNA sequencing faster, more cost effective 3NHGRI aims to make DNA sequencing faster, more cost effective 4NHGRI aims to make DNA sequencing faster, more cost effective 5NHGRI aims to make DNA sequencing faster, more cost effective 6
(Date:3/17/2010)... President of Product Development of BioMarin, will present a company update at the Barclays Capital Global Healthcare Conference in Miami on Wednesday, March 24, 2010 ... ... ... ...
(Date:3/17/2010)... ... to design their own unique shelter solution. , ... Orangeburg, NY (Vocus) March 17, 2010 -- DHS Technologies recently launched a ... , , , , ,VTAP 2.0, or the second edition of the Virtual Tactical Application ...
(Date:3/16/2010)... March 12, 2010A Materials Design client and colleague ( www.materialsdesign.com ... R&D Center, has been honored with two GM R&D Innovation ... Tribology, Multi-scale Modeling of High-temperature Deformation in Aluminum , Both ... Campbell, a former scientific director of the GM Research Laboratories, ...
(Date:3/16/2010)... SAN FRANCISCO , March 16 The Gynecologic Cancer Foundation (GCF) and ... selected as the first recipient of the $50,000 GCF/Claudia Cohen Prize for Outstanding ... 41st Annual Meeting on Women,s Cancer, meeting in San Francisco March 14-17, ... ...
Breaking Biology Technology:BioMarin to Present at the Barclays Capital Global Healthcare Conference 2BioMarin to Present at the Barclays Capital Global Healthcare Conference 3DHS Technologies Launches VTAP 2.0 2Paul Goodfellow, PhD, Awarded First GCF/Claudia Cohen Prize for Outstanding Gynecologic Cancer Researcher 2Paul Goodfellow, PhD, Awarded First GCF/Claudia Cohen Prize for Outstanding Gynecologic Cancer Researcher 3Paul Goodfellow, PhD, Awarded First GCF/Claudia Cohen Prize for Outstanding Gynecologic Cancer Researcher 4Paul Goodfellow, PhD, Awarded First GCF/Claudia Cohen Prize for Outstanding Gynecologic Cancer Researcher 5
... Science Executive,Exchange -- the professional social network for senior ... be a supporting sponsor of The,Life Science Industry Awards., ... in collaboration with,leading market research firm, BioInformatics, LLC. The ... gala ceremony beginning at 5 pm on,June 3, 2008 ...
... to Add New Drug Products to Aida Pharmaceuticals, ... ... March 27 Aida,Pharmaceuticals, Inc. (OTC Bulletin Board: AIDA) today ... a controlling interest,in one of the leading microbiology research institutes ...
... - Financing Includes Equity Investment and Line of ... Modigene Inc.,(OTC Bulletin Board: MODG), a biopharmaceutical company ... already-approved,therapeutic proteins, today announced that it has closed ... private investors and has entered into a,line of ...
Other Biology Technology:Life Science Executive Exchange 2008 To Sponsor Industry Awards 2Life Science Executive Exchange 2008 To Sponsor Industry Awards 3Aida Pharmaceuticals, Inc. Acquires High-Level Research Institute in the People's Republic of China 2Aida Pharmaceuticals, Inc. Acquires High-Level Research Institute in the People's Republic of China 3Modigene Announces Closing of $12 Million Financing by Members of The Frost Group 2Modigene Announces Closing of $12 Million Financing by Members of The Frost Group 3Modigene Announces Closing of $12 Million Financing by Members of The Frost Group 4Modigene Announces Closing of $12 Million Financing by Members of The Frost Group 5
... steadylite plus assay system offers ... sensitivity, Designed for batch-processing systems, ... higher density microplates such as ... free, Convenient storage conditions ( ...
...
... Grace's Insect Medium is formuatled ... lines including Sf9 and Sf21 cells. ... for transfectioin because it does not ... can interfere with transfection. Grace's Insect ...
D.R. Harper (1993) • Includes: essential information on taxonomy, culture and safe handling of viruses, immunology, monoclonal antibodies, antivirals and vaccines....
Biology Products: