Navigation Links
New tool tracks brain development in babies

Researchers have used a new technique to monitor brain development in infants and detect disturbances in white matter, according to a study in the July issue of Radiology.

Carola van Pul, Ph.D., and colleagues from Máxima Medical Center in Veldhoven, the Netherlands, studied seven normal infants and 10 infants with perinatal hypoxic ischemia, a type of brain injury caused by a period of oxygen and nutrient deficiency, usually as a result of complications during delivery. Hypoxic ischemic injury can result in severe motor problems.

"The pattern and extent of the brain injury largely determine the neurological and developmental consequences for the newborn," Dr. van Pul said. "The detection of injury at an early stage is essential for the development of strategies to limit permanent brain damage and to improve prognosis."

The researchers used 'diffusion tensor' magnetic resonance imaging (MRI), which depicts the diffusion, or displacement, of water molecules through tissue. Ischemia results in tissue changes that are visible with diffusion tensor imaging at least two to three hours before they can be seen on conventional MRI. The team then applied fiber tracking to construct a 3-D visualization of the brain's white matter tracts based on the diffusion tensor images. The procedure was repeated after three months to monitor the development of the injured regions. This is the first time a group of newborns has been evaluated with fiber tracking at birth and at three months.

At birth, fiber tracking showed a different fiber pattern in eight of the 10 neonates with ischemia, compared to the images obtained from the normal infants. The fiber pattern of the brain's white matter was disturbed in several areas of the brain, including the corpus callosum, which allows communication between the two hemispheres of the brain, and, most significantly, the corona radiata, which is associated with finely coordinated movement. Six of the 10 infants conti nued to exhibit disturbed fiber patterns at follow-up. All of the infants who had disturbed patterns in the corona radiata at three months had major motor problems.

"Minor white matter abnormalities seen with fiber tracking tended to resolve at three months, while marked changes persisted," Dr. van Pul said. "Further investigation is needed to determine whether the detected fiber abnormalities ultimately correlate with outcomes."

Hypoxic ischemia remains an important cause of infant mortality and morbidity, with an incidence of between one and two per 1,000 live births in the United States.


'"/>

Source:Radiological Society of North America


Related biology news :

1. Protein offers way to stop microscopic parasites in their tracks
2. Stopping smallpox in its tracks: A new anti-viral approach
3. Venom doc tracks down snake bioweapons
4. MERIS monitoring tracks planetary photosynthesis levels
5. U. of Colorado researcher identifies tracks of swimming dinosaur in Wyoming
6. Magnetic probe successfully tracks implanted cells in cancer patients
7. Research tracks whales by listening to sounds
8. Precision biochemistry tracks DNA damage in fish
9. Ghost protein leaves fresh tracks in the cell
10. New study aims to stop sepsis in its tracks
11. New imaging technique tracks traffic patterns of white blood cells
Post Your Comments:
*Name:
*Comment:
*Email:


(Date:3/30/2017)... , March 30, 2017 Trends, opportunities and ... and behavioral), by technology (fingerprint, AFIS, iris recognition, facial ... and others), by end use industry (government and law ... financial and banking, and others), and by region ( ... , Asia Pacific , and the ...
(Date:3/28/2017)... , March 28, 2017 ... Biometrics), Hardware (Camera, Monitors, Servers, Storage Devices), Software (Video ... and Region - Global Forecast to 2022", published by ... in 2016 and is projected to reach USD 75.64 ... 2017 and 2022. The base year considered for the ...
(Date:3/24/2017)... , March 24, 2017 The Controller General of ... Mr. Abdulla Algeen have received the prestigious international IAIR Award ... Continue Reading ... ... and Deputy Controller Abdulla Algeen (small picture on the right) have received ...
Breaking Biology News(10 mins):
(Date:6/23/2017)... ... June 23, 2017 , ... ... a redesigned, easier-to-navigate website for all six of their healthcare job boards. ... dentists, pharmacists, physical and occupational therapists, and biotechnicians, DocCafe.com and the MedJobCafe.com ...
(Date:6/22/2017)... Germany (PRWEB) , ... June 22, 2017 , ... ... is taking over the allergy specialists DST Diagnostische Systeme & Technologien GmbH, thereby ... all know someone who suffers from hay fever, urticaria, asthma, atopic eczema or ...
(Date:6/22/2017)... ... June 22, 2017 , ... ... release of Limfinity® version 6.5, a content-packed update to the Limfinity® framework. , ... a larger and more diverse base of customers among labs and other businesses. ...
(Date:6/20/2017)... NEWTOWN SQUARE, Pa. , June 20, 2017 /PRNewswire/ ... technology, is pleased to announce the issuance of a ... treating gout or hyperuricemia by the U.S. Patent and ... Biotech Inc., a winner of the Buzz of Bio ... , is akin to developing non-drug approaches to ...
Breaking Biology Technology: