Navigation Links
New technology addresses female fertility preservation

Women at risk for infertility, such as those needing cancer treatment, can freeze mature, fertilized eggs, but the process can take up to six weeks and for some this delay of treatment is not an option.

Immature follicles (the female egg and surrounding somatic cells) can be preserved at any time but are difficult to mature when removed from their normal environment.

A team of scientists from Northwestern University has developed a three-dimensional culture system that encapsulates follicles and allows immature eggs to grow and mature in vitro. (A follicle is a small spherical group of specialized support cells surrounding each egg.) This novel technology has already led to the live birth of healthy mice from in vitro grown follicles.

The results are published online this month by the journal Tissue Engineering.

The study shows that follicles grown individually in a three-dimensional biomaterial called alginate maintain normal connections between follicle and egg, resulting in the development of eggs, which can be fertilized and ultimately lead to healthy embryos and the birth of live mice. Previously developed methods of growing follicles or eggs outside of the body do not provide the three-dimensional support to maintain the follicle structure in which the egg must grow.

"While the research is in its early stages, this work has implications for the preservation of fertility for women and girls with cancer," said Teresa K. Woodruff, Professor of Neurobiology and Physiology who led the study together with Lonnie D. Shea, Associate Professor of Chemical and Biological Engineering. "This system establishes a core technology for human egg banks for preservation of fertility."

The technology mimics the ovary and its environment. Follicles (each follicle has one egg) from mice were grown in vitro until fully matured by providing the follicles and eggs with the necessary hormones for development while maintaining their norma
'"/>

Source:Northwestern University


Page: 1 2

Related biology news :

1. Novel technology detects human DNA mutations
2. Novel antiviral technology inhibits RSV infection in mice
3. The BIOS Initiative - open source biotechnology is born
4. Revolutionary nanotechnology illuminates brain cells at work
5. Study: homemade gene expression technology unreliable
6. First technology to remove prions that cause vCJD from blood launched
7. Integration of Agilents MS technology, Proteome Systems software to help scientists in proteomics research
8. Agilent Technologies new genome analysis technology set to accelerate Australia fight against mesothelioma
9. Recombinant DNA technology may enable oral, rather than injectable, delivery of protein drugs
10. First production of human monoclonal antibodies in chicken eggs published in Nature Biotechnology
11. Vietnam war technology could aid elephant conservation
Post Your Comments:
*Name:
*Comment:
*Email:
TAG: New technology addresses female fertility preservation

(Date:7/29/2014)... advanced optical methods and applications for imaging and manipulation ... the neurosciences were the inspiration behind Neurophotonics , ... society for optics and photonics. , The first issue ... the United States, and a special section features articles ... of the impact that optics and photonics will have ...
(Date:7/29/2014)... ice retreats, the North is changing. An ice-covered expanse ... is predicted to extend across the whole Arctic Ocean ... the potential to create Arctic swell huge waves ... the region. , A University of Washington researcher made the ... Arctic Ocean, and detected house-sized waves during a September ...
(Date:7/29/2014)... science, researchers sometimes need to get back to ... that to study the impacts of the bumphead ... ecosystems at two remote locations in the central ... and computer simulation, McCauley, an assistant professor in ... and his colleagues sought to understand whether the ...
Breaking Biology News(10 mins):SPIE launches Neurophotonics journal with special section on BRAIN Initiative 2SPIE launches Neurophotonics journal with special section on BRAIN Initiative 3Huge waves measured for first time in Arctic Ocean 2Huge waves measured for first time in Arctic Ocean 3Underwater elephants 2Underwater elephants 3
... awarded a $1.1 million Major Research Instrumentation grant ... the California NanoSystems Institute at UCLA. The award ... available super-resolution stimulated emission depletion (STED) confocal laser ... The device will be used by a ...
... Nov. 1, 2007 Researchers at Texas A&M ... in collaboration with scientists representing institutions around the ... primates. They did so after completing a multispecies ... includes primates, dermoptera (colugos) and scandentia (tree shrews). ...
... University of Pennsylvania mechanical engineer has discovered that friction ... molecular, or nanoscale, level by changing the mass of ... at a lower frequency, reducing energy lost during sliding., ... journal Science., Penn researchers, along with colleagues at the ...
Cached Biology News:$1.1 million NSF grant to fund research in advanced light microscopy at UCLA 2Researchers examine closest living relative to primates 2'Heftier' atoms reduce friction at the nanoscale, study led by Penn researcher reveals 2
(Date:7/29/2014)... The advanced optical methods and applications for ... a revolution in the neurosciences were the inspiration behind ... SPIE, the international society for optics and photonics ... of the BRAIN Initiative in the United States, and ... vision for and provide examples of the impact that ...
(Date:7/29/2014)... , July 29, 2014   Sequenom, Inc. ... that provides innovative genetic analysis solutions, and Mayo ... laboratory services in the United States ... testing patents and applications. "We have great ... patient care, and we welcome the opportunity to partner ...
(Date:7/29/2014)... LA JOLLA, Calif. , July 29, 2014 /PRNewswire/ ... therapy-based diagnostic and therapeutic company focused on extending the ... have hired Franz Och , Ph.D., an expert ... Chief Data Scientist. Och comes to HLI from Google ... of Google Translate. He will report directly to HLI ...
(Date:7/29/2014)... Cat: Can a particle be separated from its properties? ... , published the results of the first Cheshire Cat ... by Chapman University in Orange, CA, and Vienna University ... cat without a grin," thought Alice in Wonderland, "but ... thing I ever saw in my life!" Alice,s surprise ...
Breaking Biology Technology:SPIE Launches 'Neurophotonics' Journal with Special Section on BRAIN Initiative 2SPIE Launches 'Neurophotonics' Journal with Special Section on BRAIN Initiative 3SPIE Launches 'Neurophotonics' Journal with Special Section on BRAIN Initiative 4Sequenom Enters Into License Agreement With Mayo Medical Laboratories 2Sequenom Enters Into License Agreement With Mayo Medical Laboratories 3Sequenom Enters Into License Agreement With Mayo Medical Laboratories 4Franz Och, Ph.D., Expert in Machine Learning and Machine Translation, Joins Human Longevity, Inc. as Chief Data Scientist 2Franz Och, Ph.D., Expert in Machine Learning and Machine Translation, Joins Human Longevity, Inc. as Chief Data Scientist 3The quantum Cheshire cat: Scientists separate a particle from its properties 2The quantum Cheshire cat: Scientists separate a particle from its properties 3The quantum Cheshire cat: Scientists separate a particle from its properties 4
... Australian scientists have developed a handheld, battery-powered plasma-producing device that ... The device could be used in ambulance emergency calls, natural ... treatment is required in remote locations. The plasma ... of Physics D: Applied Physics is driven by a ...
... TX (March X, 2012) framergyTM, which was recently ... teamed up with engineers from the Space Alliance Technology ... funded initiative designed to speed the transfer of knowledge ... businesses, to propel commercialization of its proprietary energy-storing Metal ...
... of this diamond on quantum computing may be. A ... computer in a diamond, the first of its kind to ... from functioning properly. The demonstration shows the viability of ... systems may represent the future of quantum computing because ...
Cached Biology Technology:Handheld plasma flashlight rids skin of notorious pathogens 2framergyTM to partner with the Space Alliance Technology Outreach Program 2framergyTM to partner with the Space Alliance Technology Outreach Program 3Quantum computer built inside a diamond 2Quantum computer built inside a diamond 3
BI-1 Polyclonal Antibody Storage Temperature: -20C Shipping: gel pack Shelf-Life: 12 months...
RAW; Collected from 8-12 week old sexually mature mice that are free of common parasites; RAW Collected from 8-12 week old sexually mature mice that are free of common parasites....
... PP1, purified Formulation: 0.15M NaCl, ... 0.1mM MnCl2, 1mM MgCl2, 1mM EGTA, ... dephosphorylation of proteins Purification: DEAE chromatography, ... and gel filtration chromatography Quality Assurance: ...
Human sVCAM-1/CD106 ELI-PAIR Kit...
Biology Products: