Navigation Links
New study shows patients more willing to consider self-injectable HIV therapy than many physicians anticipate

Initial results from the OpenMind study, the largest behavioural study to look at both patients' and physicians' perceptions of HIV care in treatment-experienced patients, were revealed today at EACS. The study's findings are anticipated to help physicians implement improved care to HIV patients and help pave the way for better acceptance and integration of other new innovative drugs such as monoclonal antibodies that are increasingly being developed for the management of HIV and other diseases.

The study was conceived to look at attitudes to FUZEON (enfuvirtide), the first approved HIV fusion inhibitor, and an important option for treatment-experienced patients who face HIV resistance. FUZEON presents unique challenges because it is the first self-injectable antiretroviral whereas all other treatments are oral.

Highlights from today's data show that:

  • Patients are more willing to consider and use self-injectable therapy than many physicians anticipate
  • Three-quarters (76%) of patients would consider using a self-injectable HIV therapy if their physician recommended it
  • Worryingly, only one quarter (28%) of patients who are potentially eligible for FUZEON had actually discussed this injectable option with their physicians
  • Only 10% of eligible patients were currently prescribed FUZEON, despite the fact that it is recommended in key international HIV treatment guidelines

This study also identifies some of the main reasons why many physicians may be reluctant to prescribe a treatment of proven efficacy and safety. The reasons include; the physicians' perception that patients would be reluctant to use a self-injectable therapy, the physicians' opinion that the patient would not be able to incorporate FUZEON into their lifestyle and the potential misconception that FUZEON is not appropriately recommended in guidelines.

"Physicians' best intentions in trying to match treatments to patients may actua lly be limiting the use of FUZEON in those patients who are most likely to benefit," said Rob Horne, Professor of Psychology at the University of Brighton and OpenMind study author.

"These new insights from the OpenMind study will enable us to develop tools to facilitate more informed decisions by both patient and physician."

The study also shows that physicians' own experiences and attitudes towards self-injection are a significant motivator for its use. Physicians with considerable FUZEON experience were significantly more likely to justify using self-injectable therapy in terms of time and resources and were less likely to doubt its efficacy relative to oral therapies, when compared to physicians less experienced with this type of treatment.

Dr Mike Youle, Director of HIV Clinical Research, Royal Free Hospital, London and co-author of the OpenMind study stated, "With the increasing choice of injectable biotech drugs including monoclonal antibodies, these findings potentially have far reaching implications across a whole range of therapeutic areas. We look forward to presenting the final results and exploring possible interventions at major congresses next year."


'"/>

Source:Ketchum


Related biology news :

1. Bioartificial kidney under study at MCG
2. W.M. Keck Foundation funds study of friendly microbes
3. Yellowstone microbes fueled by hydrogen, according to U. of Colorado study
4. Genome-wide mouse study yields link to human leukemia
5. Clam embryo study shows pollutant mixture adversely affects nerve cell development
6. New imaging method gives early indication if brain cancer therapy is effective, U-M study shows
7. Same mutation aided evolution in many fish species, Stanford study finds
8. Sequencing of marine bacterium will help study of cell communication
9. Genetically modified rice in China benefits farmers health, study finds
10. A new study examines how shared pathogens affect host populations
11. NYU study reveals how brains immune system fights viral encephalitis
Post Your Comments:
*Name:
*Comment:
*Email:


(Date:3/24/2017)... Research and Markets has announced the addition of the ... Forecast to 2025" report to their offering. ... The Global Biometric Vehicle Access System ... over the next decade to reach approximately $1,580 million by 2025. ... forecasts for all the given segments on global as well as ...
(Date:3/22/2017)... , March 21, 2017 Vigilant ... company serving law enforcement agencies, announced today the appointment ... as director of public safety business development. ... law enforcement experience, including a focus on the aviation ... his most recent position, Mr. Sheridan served as the ...
(Date:3/9/2017)... , Australia , March 9, ... study data at the prestigious World Lung Imaging Workshop ... Andreas Fouras , was invited to deliver the ... pulmonary medicine. This globally recognised event brings together leaders ... share the latest developments in lung imaging. ...
Breaking Biology News(10 mins):
(Date:4/21/2017)... ... 2017 , ... Having worked on the design of the innovative Triton™ ... to top lab design architects from around the country at the Lab Design Conference ... and Engineering Greg Casey will be at the show, where they will highlight the ...
(Date:4/21/2017)... ... April 21, 2017 , ... Frederick Innovative Technology Center, ... emerging technology-based businesses, recently earned a $77,518 grant from the Rural Maryland Council ... 2004, FITCI is Frederick’s first incubator. A non-profit corporation, FITCI is a public-private ...
(Date:4/20/2017)... ... April 20, 2017 , ... Husson University will be celebrating ... body of knowledge during its Eighth Annual Research and Scholarship Day ... Atrium. During the event, undergraduates, graduate students, and faculty members from all of ...
(Date:4/20/2017)... ... April 20, 2017 , ... Open Therapeutics and the ... sharing and commercialization model. , The Center for Advancing Innovation helps institutions maximize ... effort is bringing the IP to the attention of the entrepreneurial community and ...
Breaking Biology Technology: