( ory of Functional Proteomics of Guangdo...)New study shows SARS can infect brain tissue

ory of Functional Proteomics of Guangdong Province. "There might be some ways of controlling the release of Mig, such as specific inhibitors that interfere [with] the signaling pathways involved," Dr. Jiang said. "Other approaches, such as neutralizing antibodies [and] specific binding peptides, could be tried to block brain damage induced by Mig."

Four to five percent of SARS patients treated at the Guangzhou Institute of Respiratory Diseases experienced central nervous system symptoms, said Dr. Xu; therefore, physicians need to be aware of the potential for brain infection when evaluating patients with the disease. Immunosuppressive drugs should be administered carefully and on an individual basis, as they may allow amplification of the SARS coronavirus in the brain. "Superinfection" with other pathogens could also contribute to SARS' harmful effects on the brain. "Physicians should pay more attention to the prevention of brain damage if [SARS patients] are superinfected with other conditional pathogens," according to Dr. Xu and Dr. Jiang.

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Source:Infectious Diseases Society of America


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