Navigation Links
New study reveals promising osteoporosis treatment

A New York University College of Dentistry professor has developed a calcium phosphate-based supplement that -- even at low concentrations -- significantly improves bone strength and thickness without the side effects of many current drug treatments. Dr. Racquel Z. LeGeros, a Professor of Biomaterials and Biomimetics and of Implant Dentistry, presented her research on the supplement at the American Association for Dental Research annual meeting on March 9, 2006.

Current FDA-approved pharmaceutical-based osteoporosis treatments, such as bisphosphonate drugs and hormone therapies, do not effectively repair bone that has already been lost. In fact, bisphosphonates have been shown to actually inhibit bone redevelopment. Many of these treatments also have serious side effects, including increasing the risk of heart disease, strokes, and breast cancer.

But the supplement Dr. LeGeros developed by combining magnesium (Mg), zinc (Zn), and fluoride (F) ions in a calcium-phosphate (CaP) matrix does not have the side effects of the current pharmaceutical-based treatments. Perhaps more importantly, a Mg/Zn/F-CaP supplement would be inexpensive to produce and would not require FDA approval. Dr. LeGeros' formulation could be available to market as an over-the-counter supplement, pending patent approval.

In her study, Dr. LeGeros investigated the effect in rats of Mg/Zn/F-CaP ion combinations on several bone properties: strength, thickness, quality, and composition of bones.

Dr. LeGeros divided a sample of 72 (36 males, 36 females) adult Sprague-Dawley rats (average weight, 160g) into six groups receiving the following diets: control; mineral deficiency-induced osteoporosis (MD); MD supplemented with Mg-CaP; Zn-CaP; F-CaP; and Mg/Zn/F-CaP. Each supplement was 0.6% of the MD diet. The post-mortem examination of the femurs in the MD Mg/Zn/F-CaP group showed that even this small amount of Mg/Zn/F-CaP supplement substantially improved bone strengt
'"/>

Source:New York University


Page: 1 2

Related biology news :

1. Bioartificial kidney under study at MCG
2. W.M. Keck Foundation funds study of friendly microbes
3. Yellowstone microbes fueled by hydrogen, according to U. of Colorado study
4. Genome-wide mouse study yields link to human leukemia
5. Clam embryo study shows pollutant mixture adversely affects nerve cell development
6. New imaging method gives early indication if brain cancer therapy is effective, U-M study shows
7. Same mutation aided evolution in many fish species, Stanford study finds
8. Sequencing of marine bacterium will help study of cell communication
9. Genetically modified rice in China benefits farmers health, study finds
10. A new study examines how shared pathogens affect host populations
11. NYU study reveals how brains immune system fights viral encephalitis
Post Your Comments:
*Name:
*Comment:
*Email:
TAG: New study reveals promising osteoporosis treatment

(Date:5/23/2013)... more than 284 million tons of cargo, transit the Panama ... fees for the Panama Canal Authority. Each time a ship ... used from Gatun Lake, which is also a source of ... , However, the advent of very large "super" cargo ... sea, has demanded change. The Panama Canal is being expanded ...
(Date:5/23/2013)... cancer patients unnecessarily undergo surgery or harsh treatments ... slow-growing and aggressive forms of the disease. Researchers ... Medical Institutes are developing technology that allows patients ... relatively mild treatments or take drastic measures. , ... an associate professor of biomedical engineering at Case ...
(Date:5/23/2013)... in Neuron , the team reveal the interplay ... work funded by the Wellcome Trust and BBSRC. ... stimuli we improve our perceptual abilities. While these changes ... can also affect the fidelity of that response. ... Neuroscience explains: "When you communicate with others, you can ...
Breaking Biology News(10 mins):Reforestation study shows trade-offs between water, carbon and timber 2Reforestation study shows trade-offs between water, carbon and timber 3Using big data to identify prostate cancers and best treatments 2Using big data to identify prostate cancers and best treatments 3
... have made a surprising discovery: phagocytosis depends more on ... implications for immunology, vaccine development and drug delivery, is ... Academy of Sciences by Samir Mitragotri, a UCSB professor ... The paper will be published in print on March ...
... on the path of realizing the promise of embryonic stem ... issue of Cell, the researchers have discovered unique molecular imprints ... the cells' rare ability to form almost any body cell ... that control embryonic development and probably coordinate their activity in ...
... And, at least for mice, it's one that is best made ... designed help scientists understand the brain chemicals that guide mate selection, ... a male mouse alone or a male mouse with a female. ... females. , "Our data suggest that female mice may use, or ...
Cached Biology News:Novel molecular 'signature' marks DNA of embryonic stem cells 2Novel molecular 'signature' marks DNA of embryonic stem cells 3When mice choose mates, experience counts 2
(Date:5/23/2013)... Z Trim Holdings, Inc. (OTC Markets: ZTHO), ... of industries, announced that Chef Erin Ryan ... year,s National Restaurant Association ("NRA") NRA Show, which was ... Research Chefs Association.  Chef Ryan spoke on the subject ... and the Ugly," joining four other prestigious panelists including: ...
(Date:5/23/2013)... , May 23, 2013 Pressure BioSciences, ... that the Company will host a teleconference to discuss ... a business update. The teleconference information is provided below: ... a.m. Eastern Daylight Time (EDT) Dial-in: (800) ... (302) 607-2001 (Int,l) Passcode: VS22823 For those ...
(Date:5/23/2013)... 2013 Pusan National University Yangsan Hospital, ... and contract research company focused on research and ... today a publication reporting the induction of functional ... and immunotherapeutic vaccinia JX-594 (pexastimogene devacirepvec; Jennerex Inc.). ... the May 15 th , 2013 issue of ...
(Date:5/23/2013)... Bed bugs already cost Alton Housing Authority thousands. And as ... from kmov.com suggested that the said office might need to ... be of help, My Cleaning Products gave tips how to ... service. , The report, which was posted on May ... $35,000 for bed bug elimination, My Cleaning Products shared. ...
Breaking Biology Technology:Z Trim's Chef Erin Ryan sits on Expert Panel at NRA Show 2Z Trim's Chef Erin Ryan sits on Expert Panel at NRA Show 3Pressure BioSciences, Inc. to Discuss First Quarter 2013 Financial Results and Provide Business Update 2Pusan National University Announces Science Translational Medicine Publication Highlighting Landmark Demonstration of Functional Anti-Cancer Antibody Induction in Patients Following JX-594 Treatment 2Pusan National University Announces Science Translational Medicine Publication Highlighting Landmark Demonstration of Functional Anti-Cancer Antibody Induction in Patients Following JX-594 Treatment 3Bed Bug Exterminator Service Could Cost AHA $250K, My Cleaning Products Gives Tips How to Save Apartments from Costly Bed Bug Treatment 2
... rate, we wont have enough power in 15 years, according ... a 2.5 percent growth rate, if we dont build more ... lights on in 15 years, especially in this state, said ... Ph.D, assistant professor of engineering physics at the University of ...
... and executives are reporting that there are early indications ... of 2003, which provides the necessary first steps for ... Haroldson, chief technology officer for CUNA Mutual Group said, ... regularly with technology vendors, and over the last year ...
... is experiencing problems with the SoBIG.F e-mail virus ... spread. This virus and others, which have ravaged computers ... has affected the e-mail operations for all users. UW-Madison ... at the height of the virus problem. , ,The ...
Cached Biology Technology:Software Company Tackles Energy Shortage Issues 2IT Spending to Increase in Second Half of 2003 2IT Spending to Increase in Second Half of 2003 3IT Spending to Increase in Second Half of 2003 4IT Spending to Increase in Second Half of 2003 5UW-Madison Battles Prolific Computer Virus 2
GLP-compliant, CLIA-certified DNA sequencing service. ASQ and SQA certified quality assurance staff. Auditors welcome....
Sequencing and primer design rolled into one. Just give us your clone and a reference sequence, and we'll do the rest. Single-strand or double-strand coverage. Guaranteed results....
... polyclonal antibody to human XAB2 (amino terminus) ... identified through its interaction with XPA. Immunoprecipitation ... of XAB2 interacts with the transcription-coupled repair-specific ... with RNA polymerase II. Microinjection experiments with ...
... microplate coating using advanced automated high throughput microplate processing equipment ... can also accommodate virtually any lot size of the following ... 8 and 12 well strips, ... 384 well microplate, ...
Biology Products: