Navigation Links
New research shows why too much memory may be a bad thing

xcess neurogenesis can be detrimental to some memory processes."

"We believe these findings have important implications for diverse disciplines ranging from medicine to artificial intelligence," said Dr. Malleret. "In medicine, these findings have significant implications for possible therapeutic interventions to improve memory ?a careful balance of neurogenesis would need to be struck to improve memory without overwhelming it with too much activity."

Many scientists had believed that neurogenesis in the hippocampus, and specifically, the dentate gyrus region, was wholly beneficial to memory. Previous research by Dr. Malleret with co-first author Michael D. Saxe, Ph.D., who was at Columbia when the research took place and is now at the Salk Institute in San Diego, Calif., found that reducing neurogenesis causes long-term memory deficits.

Based on this research, Drs. Malleret and Saxe hypothesized that the growth of too many new neurons could actually be more harmful than helpful to working memory. To examine this hypothesis, they designed working memory tests for two independent groups of mice in which neurogenesis in the hippocampus regions was suppressed. Results of the tests, in which mice had to locate food within specific areas of a maze, showed that mice in which neurogenesis had been halted made more correct choices and found the food faster.

"In our world, we are constantly bombarded by new information so we are constantly filtering –and if we did not do this, we would be overwhelmed," said Dr. Malleret. "Our research indicates that those with better working memory may have fewer new neurons being developed in their hippocampus, which helps them forget old and useless information sooner and enable them to take in new information faster."
'"/>

Source:Columbia University Medical Center


Page: 1 2

Related biology news :

1. Columbia research lifts major hurdle to gene therapy for cancer
2. U of M researcher examines newly emerging deadly disease
3. NYU researchers simulate molecular biological clock
4. First atlas of key brain genes could speed research on cancer, neurological diseases
5. New research questions basic tenet of neuron function
6. Vital step in cellular migration described by UCSD medical researchers
7. ASU researchers finds novel chemistry at work to provide parrots vibrant red colors
8. UCSD researchers maintain stem cells without contaminated animal feeder layers
9. Why do insects stop breathing? To avoid damage from too much oxygen, say researchers
10. New protein discovered by Hebrew University researchers
11. First real-time view of developing neurons reveals surprises, say Stanford researchers
Post Your Comments:
*Name:
*Comment:
*Email:
TAG: New research shows why too much memory may bad thing

(Date:7/29/2014)... the first to show that while the impact of ... negative effects may be reduced by maintaining a healthy ... participants who exercised, slept well and ate well had ... healthy lifestyles, even when they had similar levels of ... in the department of psychiatry at UCSF. "It,s very ...
(Date:7/28/2014)... discovery of two additional coral communities showing signs of damage ... of the 2010 spill in the Gulf of Mexico. The ... professor of biology at Penn State University. A paper describing ... in the Gulf of Mexico will be published during the ... of the journal Proceedings of the National Academy of ...
(Date:7/28/2014)... led by the University of Arizona has sequenced the ... will enhance scientists, and agriculturalists, understanding of the growing ... development of new rice varieties that are better able ... global hunger challenges. , The paper, "The genome sequence ... for independent domestication," was published online in Nature ...
Breaking Biology News(10 mins):Healthy lifestyle may buffer against stress-related cell aging, study says 2Impact of Deepwater Horizon oil spill on coral is deeper and broader than predicted 2Generating a genome to feed the world: UA-led team sequences African rice 2Generating a genome to feed the world: UA-led team sequences African rice 3Generating a genome to feed the world: UA-led team sequences African rice 4
... and the United States have completed the draft genome ... bacteria that cause citrus canker. Citrus canker, a belligerent ... the United States, South America, and Asia, causes millions ... of citrus crops such as oranges, limes, and grapefruit. ...
... evolve or not to evolve? That is the question scientists ... answering following a groundbreaking new study into the colourful hamlet ... in the vast marine environment. The new findings, published online ... significantly improve our understanding of speciation the evolutionary process ...
... defend themselves in some way, they would certainly be gobbled ... little insects to large mammalian herbivores. Indeed, not only ... kind of defense. When a plant has several options, ... the same tissues or defend different tissues in different ways? ...
Cached Biology News:Genomes of citrus canker pathogens decoded 2Genomes of citrus canker pathogens decoded 3Hamlet fish sheds light on evolution of marine species 2Making its predators tremble: Multiple defenses act synergistically in aspen 2Making its predators tremble: Multiple defenses act synergistically in aspen 3
(Date:7/29/2014)... The first product launch from start-up ... to robotics. What sets Droidles completely apart from other ... allows them to communicate, share code with each other ... , “The invention is the system,” said Hurley Research ... life of their own, both physically and on the ...
(Date:7/29/2014)... The prestigious "Discovery or Exploration in History ... to Juliana Hillis and Kaylie O’Connell, students at Stoneham ... an Egg, Everything: America’s First IVF Baby". This project ... National History Day program during a week-long final competition ... Washington, D.C. , The growing popularity of the assisted ...
(Date:7/29/2014)... White papers by Clinovo on ... technologies, have been published by leading pharmaceutical publications Data ... line of white papers by Clinovo to have been ... Pharmaceutical Online, and OpenHealthNews. , At the request of ... Marc Desgrousilliers, 'The Five Essentials of Cloud Computing ...
(Date:7/29/2014)... 2014 PlaqueTec ... Erfassung biologischer Daten in Verbindung mit Herzerkrankungen ... Das LBS nimmt gleichzeitig mehrere Blutproben von ... und sucht erhöhte biologische Aktivitäten in erkrankten ... Entdeckung und Entwicklung neuer Medikamente und Therapeutika ...
Breaking Biology Technology:Droidles, the Social Network of Robots and Open Source Platform for the Internet of Things, Launches for Crowd Funding on IndieGoGo.com 2In Vitro Fertilization (IVF) was the Subject of This Year’s Winning Entry for the Prestigious Library of Congress “Discovery or Exploration in History Award” 2In Vitro Fertilization (IVF) was the Subject of This Year’s Winning Entry for the Prestigious Library of Congress “Discovery or Exploration in History Award” 3Clinovo White Papers Published in Summer 2014 Editions of Leading Medical Device & Pharmaceutical Publications 2Clinovo White Papers Published in Summer 2014 Editions of Leading Medical Device & Pharmaceutical Publications 3PlaqueTec sichert sich CE-Kennzeichnung für Liquid Biopsy System - bahnbrechende Innovation zur Erfassung neuer biologischer Informationen aus erkranktem Herzkranzgefäß 2PlaqueTec sichert sich CE-Kennzeichnung für Liquid Biopsy System - bahnbrechende Innovation zur Erfassung neuer biologischer Informationen aus erkranktem Herzkranzgefäß 3PlaqueTec sichert sich CE-Kennzeichnung für Liquid Biopsy System - bahnbrechende Innovation zur Erfassung neuer biologischer Informationen aus erkranktem Herzkranzgefäß 4
... A discovery by scientists at the University of East ... that use domestic or agricultural waste to generate clean ... Proceedings of the National Academy of Sciences ... the mechanism by which some bacteria survive by ,breathing ...
... , , FREMONT, Calif., Dec. ... a leading developer of state-of-the-art genetic analysis systems, today ... Panel for its innovative service for gene-expression profiling using ... Panel provides the most comprehensive human microRNA panel of ...
... , , , , WALTHAM, Mass., Dec. ... research and advisory firms for pharmaceutical and healthcare issues, ... Ortho Biotech/Janssen-Cilag,s Stelara and Abbott,s briakinumab (both interleukin inhibitors) ... 2012 in the drug market for moderate to severe ...
Cached Biology Technology:'Rock-breathing' bacteria could generate electricity and clean up oil spills 2WaferGen to Launch Human MicroRNA Panel for Gene-Expression Profiling of 885 MicroRNA for Its Service Using the SmartChip(TM) Real-Time PCR System 2WaferGen to Launch Human MicroRNA Panel for Gene-Expression Profiling of 885 MicroRNA for Its Service Using the SmartChip(TM) Real-Time PCR System 3WaferGen to Launch Human MicroRNA Panel for Gene-Expression Profiling of 885 MicroRNA for Its Service Using the SmartChip(TM) Real-Time PCR System 4In 2012, Stelara and Briakinumab Will Capture 22 Percent of the Biologics Share in the Moderate to Severe Psoriasis Drug Market 2In 2012, Stelara and Briakinumab Will Capture 22 Percent of the Biologics Share in the Moderate to Severe Psoriasis Drug Market 3
... For the ultimate in utility and ... to meet the needs of the researcher. ... interior dimensions or as sheet material that ... enclosures. These isolators are autoclavable and non-cytotoxic ...
2,4-Dinitrophenyl hapten is conjugated to Human Serum Albumin (HSA) protein through lysine....
IC50: 3 ng/ml · Limit of detection: 0.5 ng/ml...
Antibodies were affinity purified using epitopes specific to PPP1CC immobilized on solid support....
Biology Products: