Navigation Links
New research examines genetics of successful aging

A study released today at the American College of Neuropsychopharmacology's Annual Meeting revealed that scientists have identified genes related to reaching age 90 with preserved cognition. The study, which was funded by the National Institutes of Health and conducted at the University of Pittsburgh, is among the first to identify genetic links to cognitive longevity.

"While successful aging has been defined in many ways, we focused on individuals who had reached at least 90 without significant decline in mental capacity," said lead researcher George S. Zubenko, MD, PhD, Professor of Psychiatry and Biological Sciences at the University of Pittsburgh School of Medicine. "Not only is this a goal that many of us share, this definition of 'successful aging' can be determined objectively and consistently across subjects--an important requirement of scientific studies."

While previous research found that genes make important contributions to exceptional longevity, the goal of this study was to identify regions of the human genome that contributed, along with lifestyle factors, to reaching age 90 with preserved cognition.

The study involved 100 people age 90 and older with preserved cognition, as measured by clinical and psychometric assessments. Half of the subjects were male, half were female. Using a novel genome survey method, scientists compared the DNA of the study sample with that of 100 young adults, aged 18-25 years old, who were matched for sex, race, ethnicity and geographic location. Specifically, Dr. Zubenko and his research team attempted to identify specific genetic sequences present in older individuals that may be linked to reaching older ages with preserved cognitive abilities, or conversely, specific genetic sequences present in younger individuals (and not present in those over age 90) that may impede successful aging. The study also looked at a variety of lifestyle factors, such as smoking and alcohol consumption, with t
'"/>

Source:GYMR


Page: 1 2

Related biology news :

1. Columbia research lifts major hurdle to gene therapy for cancer
2. U of M researcher examines newly emerging deadly disease
3. NYU researchers simulate molecular biological clock
4. First atlas of key brain genes could speed research on cancer, neurological diseases
5. New research questions basic tenet of neuron function
6. Vital step in cellular migration described by UCSD medical researchers
7. ASU researchers finds novel chemistry at work to provide parrots vibrant red colors
8. UCSD researchers maintain stem cells without contaminated animal feeder layers
9. Why do insects stop breathing? To avoid damage from too much oxygen, say researchers
10. New protein discovered by Hebrew University researchers
11. First real-time view of developing neurons reveals surprises, say Stanford researchers
Post Your Comments:
*Name:
*Comment:
*Email:
TAG: New research examines genetics successful aging

(Date:7/9/2014)... which animals can be found, concern mounts over the ... range for a host mean new territory for its ... of UC Santa Barbara scientists, including parasitologists Ryan Hechinger ... Journal of Biogeography , Hechinger, Kuris and colleagues ... Hosts may actually lose their parasites when the hosts ...
(Date:7/9/2014)... derived from the oils produced by algae may offer ... this goal, optimization of cost effective strategies for large-scale ... needed. Sapphire Energy has developed an innovative solution to ... systems, described in Industrial Biotechnology , a peer-reviewed ... is available on the Industrial Biotechnology ...
(Date:7/9/2014)... Ill. With over 100 diseases that can attack ... top of the most wanted list? University of Illinois ... that more research is needed on the fungus that ... with cool, damp growing conditions but Macrophomina phaseolina ... and dry drought conditions. , "As the climate continues ...
Breaking Biology News(10 mins):Not at home on the range 2Not at home on the range 3Not at home on the range 4Controlling contamination in open algae ponds for biofuels 2Climate change provides good growing conditions for charcoal rot in soybeans 2Climate change provides good growing conditions for charcoal rot in soybeans 3
... The University of Nottingham are to receive more than 5 ... make rural living in both the UK and India more ... opportunities for small scale energy generation through renewable sources, developing ... of mobile technologies to grow wealth in rural communities. , ...
... landscapes have undergone great change in recent decades, but species ... roe deer, Spanish ibex, red deer and wild boar. ... the effects of changes in land use on the past, ... last few decades there has been an increase in the ...
... serious gastric disorders including stomach cancer may be a step ... chemist. In the first published study of its kind, ... found a carbohydrate-based antigen caused mice to develop antibodies against ... the first jab at a sugar-based vaccine against Helicobacter ...
Cached Biology News:Nottingham researchers help bridge the urban and rural divide in the UK and India 2Nottingham researchers help bridge the urban and rural divide in the UK and India 3Nottingham researchers help bridge the urban and rural divide in the UK and India 4Changes in land use favor the expansion of wild ungulates 2
(Date:1/14/2014)... EquitiesIQ, a leading informational research provider, has ... an emerging biomedical company acquiring, developing, manufacturing, and marketing ... Free report download: http://equitiesiq.com/reports/alliqua/ , In late ... and Board, which launched the company’s new strategy to ...
(Date:1/14/2014)... January 14, 2014 In recent years, ... and methods in product development and promotion has led ... This mistrust, fueled by concerns about the insidious impact ... reports of spectacular fines to the world’s biggest pharmas ...
(Date:1/14/2014)... Cardiff, UK (PRWEB) January 13, 2014 ... leader with more than 20 years in the industry, ... and photonics . Hainsey will serve as the society’s ... have Dr. Hainsey join SPIE as our Technology Strategist, ...
(Date:1/14/2014)... (PRWEB) January 14, 2014 BioMedomics, Inc. ... ultra-sensitive POC diagnostic platforms and novel disease specific POC tests, ... of financing netting a total of $690,000. The investment is ... in the company. This group of private investors has significant ...
Breaking Biology Technology:EquitiesIQ Initiates Coverage of Alliqua, Inc. 2EquitiesIQ Initiates Coverage of Alliqua, Inc. 3The Sunshine Act: Necessary Regulation or Unnecessary Dysregulation? New Life Science Webinar Hosted by Xtalks and IRB Services 2The Sunshine Act: Necessary Regulation or Unnecessary Dysregulation? New Life Science Webinar Hosted by Xtalks and IRB Services 3Photonics R&D Leader Bob Hainsey Joins SPIE Technical Staff 2BioMedomics, Inc. Closes $690K Round of Financing 2
... naturally occurring antibodies contained in, GAMMAGARD LIQUID ... disease, CHICAGO, April 15 The University ... (NYSE: BAX ) today,announced data from a ... [Immune Globulin Intravenous (Human)] (IGIV),marketed as KIOVIG in ...
... BIRMINGHAM, Ala., and CEDARHURST, N.Y., April 15 ,BioHorizons, ... of Implant Logic Systems, Ltd. ("ILS"), first announced ... as a subsidiary of,BioHorizons. Steve Boggan, CEO of ... offering to include VIP Virtual Implant Placement,planning software ...
... PALO ALTO, Calif., April 15 CV Therapeutics,Inc. ... Capital has agreed to pay,CV Therapeutics up to ... percent of,CV Therapeutics, royalty on North American sales ... on closing,of the transaction and could receive a ...
Cached Biology Technology:Study Suggests GAMMAGARD LIQUID May Target the Primary Pathway Involved in Alzheimer's Disease 2Study Suggests GAMMAGARD LIQUID May Target the Primary Pathway Involved in Alzheimer's Disease 3Study Suggests GAMMAGARD LIQUID May Target the Primary Pathway Involved in Alzheimer's Disease 4Study Suggests GAMMAGARD LIQUID May Target the Primary Pathway Involved in Alzheimer's Disease 5BioHorizons Announces the Purchase of Implant Logic Systems 2CV Therapeutics Announces $185 Million Transaction with TPG-Axon Capital for Half of Royalty for Lexiscan(TM) (regadenoson) Injection 2CV Therapeutics Announces $185 Million Transaction with TPG-Axon Capital for Half of Royalty for Lexiscan(TM) (regadenoson) Injection 3
... Channel Cell Lines ,High Quality, Functionally-Validated, Ion ... well known for having a critical role ... have a key function in pain, CNS ... channels have been investigated in therapeutic areas, ...
Mouse monoclonal antibody raised against a full length recombinant SLC25A11. NCBI Entrez Gene ID = SLC25A11...
... antibody raised against a partial ... Immunogen: TOPORS (NP_005793, 98 ... recombinant protein with GST tag. ... NM_005802 ...
Mouse monoclonal antibody raised against a full length recombinant SNAPC5. NCBI Entrez Gene ID = SNAPC5...
Biology Products: