Navigation Links
New recommendations against a major opportunistic infection -- cryptococcosis

CRNS and the Institut Pasteur conducted research in France on patients diagnosed with cryptococcosis which ranks second among fatal opportunistic infections in patients infected by HIV and who are profoundly immunosuppressed. A multicentric prospective study, published on February 5 2007 in PLoS Medicine, uncovers parameters associated with more severe infections, such as the patient’s sex and the infecting serotype. In light of the results, the authors propose a modification in the therapeutic treatment of individuals suffering from cryptococcosis.

Caused by a microscopic fungus, Cryptococcus neoformans, cryptococcosis affects immunosuppressed individuals, most of whom are infected by HIV, but who also suffer from other immunological disorders or who are receiving immunosuppressive treatments. Most often, the fungus causes meningoencephalitis, but the infection can also be localised in the lungs. The incidence of cryptococcosis in France has decreased by half with the availability of antiretroviral combination therapies, and now represents around 100 cases annually. However, in Africa and Asia, it remains the second most fatal opportunistic infection after tuberculosis in individuals infected by HIV, in some countries affecting up to 30% of them in the absence of access to antiretroviral drugs. It is now the first cause of meningitis among adults in Africa.

A vast cohort study was performed on patients diagnosed with cryptococcosis between 1997 and 2001 in France by Françoise Dromer, head of the Molecular Mycology unit (CNRS URA 3012) and National Reference Centre for Mycoses and Antifungals at the Institut Pasteur, and Olivier Lortholary, from the same Pasteur unit and the Necker-Pasteur Infectiology Centre, in collaboration with the French Cryptococcosis Study Group, which is composed of mycologists and clinicians in 77 centres throughout the territory.

Aiming to analyse the factors influencing the clinical presentation of the disease
'"/>

Source:CNRS


Page: 1 2 3

Related biology news :

1. Enzyme, lost in most mammals, is shown to protect against UV-induced skin cancer
2. Bound for destruction: Ubiquitination protects against improper Notch signaling
3. Female sex hormones play a vital role in defense against sexually transmitted diseases
4. In the sea slugs defense against lobsters, confusion is key
5. Antibodies from plants protect against anthrax
6. Molecular models advance the fight against malaria
7. Sickle cell and protection against malaria
8. Live vaccines more effective against horse herpes virus
9. Turning viruses into allies against cancer
10. Friendly bacteria in humans may protect against HIV
11. NSAID drug protects against intestinal tumors in mice, despite poor diet and gene losses
Post Your Comments:
(Date:12/10/2014)... , Dec. 08, 2014 Research and ... the addition of the "Biometrics Market in ... http://photos.prnewswire.com/prnh/20130307/600769 ... projects such as rural banking and upgradation of ... trends witnessed in the market. Besides the aforementioned ...
(Date:12/3/2014)...   Marvin Test Solutions , a trusted ... military, aerospace, and manufacturing organizations, today announced the ... TS-900 PXI semiconductor test platform . The TS-960 ... to customers at a fraction of the footprint ... "Our semiconductor customers asked for ...
(Date:11/21/2014)... REDMOND, Wash. , Nov. 20, 2014 ... access for the Internet of Things (IoT), today announced ... position of chief operating officer. Previously a strategic advisor ... marketing, finance, and operations. Mr. Traynor is based out ... . He reports to Chris Muench , ...
Breaking Biology News(10 mins):Biometrics Market in Japan 2014-2018: Key Vendors are DDS, Fujitsu, Hitachi and NEC 2Marvin Test Solutions Brings New Capabilities to PXI-Based Semiconductor Test with TS-960 2Marvin Test Solutions Brings New Capabilities to PXI-Based Semiconductor Test with TS-960 3C-Labs Names Former Microsoft and Bsquare Executive as Chief Operating Officer 2
... An early type of antibiotic-resistant bacteria that caused a ... as one of the community-acquired MRSA 'superbugs', according to ... April 2005). , This "re-equipping and re-emergence" of a ... mean that community acquired MRSA will spread faster and ...
... have been calling for an improved database that would ... strategies. Botanists at the University of Bonn have now ... publication, in the Journal of Biogeography, of a world ... in 867 zones, known as ecoregions. "This makes the ...
... the Universitat Autònoma de Barcelona has developed new miniature ... size and thickness as a fingernail and reduce the ... or a few hours, depending on each chain. These ... from paternity tests and identifying people to detecting genetically ...
Cached Biology News:Community MRSA is re-emergence of 1950s pandemic, study suggests 2Scientists map the world for nature conservation 2New miniaturised chip dramatically reduces time taken for DNA analysis 2New miniaturised chip dramatically reduces time taken for DNA analysis 3
(Date:12/24/2014)... NEW YORK , Dec. 23, 2014 ... pilot study of mazindol in children with attention deficit/hyperactivity ... in December 2014 . The paper, ... with attention deficit/hyperactivity disorder" ( Konofal et al, ... 1;8:2321-2332. eCollection 2014 ) shows that mazindol might ...
(Date:12/22/2014)... 2014   Synthetic Biologics, Inc. ... therapies for serious infections and diseases, with ... announced positive topline safety and tolerability results ... SYN-004, the Company,s investigational oral beta-lactamase enzyme ... (C. difficile) infection, antibiotic-associated diarrhea and ...
(Date:12/22/2014)... 22, 2014  Alternative Energy & Environmental Solutions, ... signed a letter of intent to acquire BioTechPharma ... patented a nanotechnology-based development platform used to create ... rapid on-site collection and testing to identify infectious ... in an immediate, non-invasive and cost-effective manner. ...
(Date:12/22/2014)... MISSION VIEJO, Calif. , Dec. 22, 2014 /PRNewswire/ ... announce that CoPatient, an online medical bill review and ... newest offering in the FREE WellCard Savings discount health ... a medical bill that was more than they expected ... help members reduce health care costs, WellCard Savings is ...
Breaking Biology Technology:Redefining ADHD: A New Approach & A Shift of Paradigm in ADHD Therapeutics 2Redefining ADHD: A New Approach & A Shift of Paradigm in ADHD Therapeutics 3Synthetic Biologics Announces Positive Topline Results from Phase 1a Trial of SYN-004 for the Prevention of C. difficile Infection 2Synthetic Biologics Announces Positive Topline Results from Phase 1a Trial of SYN-004 for the Prevention of C. difficile Infection 3Synthetic Biologics Announces Positive Topline Results from Phase 1a Trial of SYN-004 for the Prevention of C. difficile Infection 4Synthetic Biologics Announces Positive Topline Results from Phase 1a Trial of SYN-004 for the Prevention of C. difficile Infection 5ALNE Announces Intention To Acquire BioTechPharma 2WellCard Savings Announces CoPatient Medical Bill Review Service for Members 2
... transportation firms are still popular among IT professionals, according ... , ,The magazine released its 12th annual "100 Best ... American Family Insurance Group 30th in the ... year's study recognized companies that create meaningful work for ...
... FedEx/Kinkos needed to dispose of 1,100 used copier machines, it ... $200,000 to the company and a harder-to-calculate cost to ... recycle the machines by donating them to non-profit organizations. FedEx/Kinkos ... you ever wondered about what happened to Scott McCallum, Aidmatrix ...
... as businesses seek to protect and enhance the value ... result of the business' products and services. Each year, ... many of them for federal trademark registration. Indeed, applications ... good leading indicator of economic conditions (a steep drop ...
Cached Biology Technology:Two Wisconsin companies hold spots on Computerworld employee survey 2Internet charity link has a Wisconsin flavor in CEO Scott McCallum 2Internet charity link has a Wisconsin flavor in CEO Scott McCallum 3Why file for trademark protection? 2Why file for trademark protection? 3Why file for trademark protection? 4
A set of five proteins which can be used to calibrate a Matrix-assisted laser desorption/ionization time-of-flight (MALDI-TOF) or Electrospray Ionization (ESI) mass spectrometer....
... A number of modifications of Grace's ... the late 1960's and 1970's. Many of ... Hink for the growth of cells derived ... represents the modification known as TNM-FH. The ...
... GST•Tag™ Ek Adaptor encodes a T7 promoter, ... (rbs), ATG translation initation codon and an ... has been reported to enhance the production ... its fusion partners. The GST•Tag is a ...
...
Biology Products: