Navigation Links
New nanotechnology able to examine single molecules, aiding in determining gene expression

A new nanotechnology that can examine single molecules in order to determine gene expression, paving the way for scientists to more accurately examine single cancer cells, has been developed by an interdisciplinary team of researchers at UCLA's California Nanosystems Institute (CNSI), New York University's Courant Institute of Mathematical Sciences, and Veeco Instruments, a nanotechnology company. Their work appears in the January issue of the journal Nanotechnology.

Previously, researchers have been able to determine gene expression using microarray technology or DNA sequencing. However, such processes could not effectively measure single gene transcripts—the building blocks of gene expression. With their new approach, the researchers of the work reported in Nanotechnology were able to isolate and identify individual transcript molecules—a sensitivity not achieved with earlier methods.

"Gene expression profiling is used widely in basic biological research and drug discovery," said Jason Reed of UCLA's Department of Chemistry and Biochemistry and the study's lead author. "Scientists have been hampered in their efforts to unlock the secrets of gene transcription in individual cells by the minute amount of material that must be analyzed. Nanotechnology allows us to push down to the level of individual transcript molecules."

"We are likely to see more of these kinds of highly multi-disciplinary research aimed at single molecule sequencing, genomics, epigenomic, and proteomic analysis in the future," added Bud Mishra, a professor of Computer Science, Mathematics, and Cell Biology from NYU's Courant Institute and School of Medicine. "The most exciting aspect of this approach is that as we understand how to intelligently combine various components of genomics, robotics, informatics, and nanotechnology—the so-called GRIN technology—the resulting systems will become simple, inexpensive, and commonplace."


'"/>

Source:New York University


Page: 1

Related biology news :

1. Revolutionary nanotechnology illuminates brain cells at work
2. Silver bullet: UGA researchers use laser, nanotechnology to rapidly detect viruses
3. Iowa State scientists demonstrate first use of nanotechnology to enter plant cells
4. U of M researcher examines newly emerging deadly disease
5. A new study examines how shared pathogens affect host populations
6. New study examines how sense of smell affects mating and aggression in mice
7. New research examines genetics of successful aging
8. UCLA paper examines how one disease may prevent another
9. U of M study examines kidney stone prevention in astronauts
10. New research examines genetics of successful aging
11. Plants role in global warming re-examined
Post Your Comments:
*Name:
*Comment:
*Email:


(Date:5/16/2017)... --  Bridge Patient Portal , an enterprise patient ... Systems , an electronic medical record solutions developer ... a partnership to build an interface between the ... products, including Centricity Practice Solution (CPS), Centricity Business ... integrations will allow healthcare delivery networks using GE ...
(Date:4/18/2017)... -- Socionext Inc., a global expert in SoC-based imaging and computing solutions, ... which features the company,s hybrid codec technology. A demonstration utilizing TeraFaces ... will be showcased during the upcoming Medtec Japan at Tokyo Big ... Las Vegas Convention Center April 24-27. ... Click here for an image of ...
(Date:4/11/2017)... BEACH GARDENS, Fla. , April 11, 2017 ... identity management and secure authentication solutions, today announced ... contract by Intelligence Advanced Research Projects Activity (IARPA) ... for IARPA,s Thor program. "Innovation has ... onset and IARPA,s Thor program will allow us ...
Breaking Biology News(10 mins):
(Date:5/21/2017)... ... May 19, 2017 , ... Ovation ... of the American Association of Bioanalysts (AAB) and the College of Reproductive Biology ... conference reinforces AAB’s commitment to excellence in clinical laboratory services and regulations. ...
(Date:5/18/2017)... ... May 18, 2017 , ... Dr. ... 2017 at the Prince Of Wales Private Hospital. The procedure was performed on ... The patient failed conservative treatments prior to undergoing surgery. , The AxioMed viscoelastic ...
(Date:5/18/2017)... ... May 17, 2017 , ... ... its scientific power by providing investigators access to a high-profile scientific advisory ... the scientific advisory board. “We are committed to offering superior services and ...
(Date:5/18/2017)... (PRWEB) , ... May 17, 2017 , ... ... construction, announced today that their Chief Executive Officer, Maik Jornitz, was recognized as ... UK publication’s Power List celebrates 100 individuals “involved in bettering the pharma industry ...
Breaking Biology Technology: