Navigation Links
New nanotechnology able to examine single molecules, aiding in determining gene expression

A new nanotechnology that can examine single molecules in order to determine gene expression, paving the way for scientists to more accurately examine single cancer cells, has been developed by an interdisciplinary team of researchers at UCLA's California Nanosystems Institute (CNSI), New York University's Courant Institute of Mathematical Sciences, and Veeco Instruments, a nanotechnology company. Their work appears in the January issue of the journal Nanotechnology.

Previously, researchers have been able to determine gene expression using microarray technology or DNA sequencing. However, such processes could not effectively measure single gene transcripts—the building blocks of gene expression. With their new approach, the researchers of the work reported in Nanotechnology were able to isolate and identify individual transcript molecules—a sensitivity not achieved with earlier methods.

"Gene expression profiling is used widely in basic biological research and drug discovery," said Jason Reed of UCLA's Department of Chemistry and Biochemistry and the study's lead author. "Scientists have been hampered in their efforts to unlock the secrets of gene transcription in individual cells by the minute amount of material that must be analyzed. Nanotechnology allows us to push down to the level of individual transcript molecules."

"We are likely to see more of these kinds of highly multi-disciplinary research aimed at single molecule sequencing, genomics, epigenomic, and proteomic analysis in the future," added Bud Mishra, a professor of Computer Science, Mathematics, and Cell Biology from NYU's Courant Institute and School of Medicine. "The most exciting aspect of this approach is that as we understand how to intelligently combine various components of genomics, robotics, informatics, and nanotechnology—the so-called GRIN technology—the resulting systems will become simple, inexpensive, and commonplace."


'"/>

Source:New York University


Page: 1

Related biology news :

1. Revolutionary nanotechnology illuminates brain cells at work
2. Silver bullet: UGA researchers use laser, nanotechnology to rapidly detect viruses
3. Iowa State scientists demonstrate first use of nanotechnology to enter plant cells
4. U of M researcher examines newly emerging deadly disease
5. A new study examines how shared pathogens affect host populations
6. New study examines how sense of smell affects mating and aggression in mice
7. New research examines genetics of successful aging
8. UCLA paper examines how one disease may prevent another
9. U of M study examines kidney stone prevention in astronauts
10. New research examines genetics of successful aging
11. Plants role in global warming re-examined
Post Your Comments:
*Name:
*Comment:
*Email:


(Date:1/12/2017)... Jan. 12, 2017  Trovagene, Inc. (NASDAQ: ... technologies, today announced that it has signed agreements with ... and the Middle East for ... marks the first wave of international distribution agreements for ... blood samples. The initial partners will introduce ...
(Date:1/11/2017)... N.J. , Jan. 11, 2017  Michael Johnson, co-founder of ... Venture Capital Group, Inc., has been named to the elite "Forbes ... 27,  was one of 600 people in 20 fields nationwide to ... percent of the 15,000 applicants were selected. ... He is currently a PhD candidate at ...
(Date:1/4/2017)... , Jan. 4, 2017  For the thousands of attendees at this ... leader in connected health and biometric measurement devices and services, will be ... On display in A&D Medical,s special CES Exhibit Suite , ... ongoing expansion of the company,s WellnessConnected product platform.  ... ...
Breaking Biology News(10 mins):
(Date:1/18/2017)... IRVING, Texas , Jan. 18, 2017 /PRNewswire/ ... science, and the Lustgarten Foundation, the largest private ... support a clinical trial evaluating the impact of ... is providing clinical trial enrollment services to identify ... and facilitate communication between treating physicians and study ...
(Date:1/17/2017)... 17, 2017 The Global Implantable Biomaterials ... of around 7.5% over the next decade to ... the prominent trends that the market is witnessing ... & graft transplant surgeries and medical implants and ... is categorized into immunomodulatory biomaterials, natural, polymers, hydrogels ...
(Date:1/17/2017)... Jan. 17, 2017 Noom Inc. ... the first to offer fully Spanish behavior change ... Noom,s Spanish diabetes prevention and healthy weight ... accessibility of lifestyle interventions among Hispanic Americans who ... Noom,s robust food database, program-specific curriculum content and ...
(Date:1/17/2017)... , ... January 17, 2017 , ... Pono Ola ... peaceful and healthy lifestyle, announced today the official launch of its much-anticipated Pono Board: ... mind. , In development for over a year, the patented Pono Board ...
Breaking Biology Technology: