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New method shows it is possible to grow bone for grafts within a patient's body

ed it slightly. When they had created a cavity the size and shape that they wanted, the researchers, Next, they removed the water and replaced it with a gel that is commercially available and approved by the FDA for delivery of cells within the human body. They chose the material because it contained calcium, a known trigger for bone growth. Their major concern was that the bioreactor would fill with scar tissue instead of bone, but that didn't happen. Instead, it filled with bone that is indistinguishable from the original bone.

The scientists intend to proceed with the large animal studies and clinical trials necessary to determine if the procedure will work in humans and, if it does, to get it approved for human treatment. At the same time, they hope to test the approach with the liver and pancreas, which have outer layers similar to the periosteum.


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Source:Vanderbilt University


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