Navigation Links
New method shows it is possible to grow bone for grafts within a patient's body

bone outside of the body--in vitro--have all failed. Recent attempts to stimulate bone growth within the body--in vivo--have had limited success but have proven to be extremely complex, expensive and unreliable.

Shastri's and his colleagues took a new approach that has proven to be surprisingly simple. They decided to take advantage of the body's natural wound-healing response and create a special zone on the surface of a healthy bone in hopes that the body would respond by filling the space with new bone. The approach lived up to their highest expectations. Working with mature rabbits, a species with bones that are very similar to those of humans, the researchers were delighted to find that this zone, which they have dubbed the "in vivo bioreactor," filled healthy bone in about six weeks. And it did so without having to coax the bone to grow by applying the growth factors required by previous in vivo efforts. Furthermore, they found that the new bone can be detached easily before it fuses with the old bone, leaving the old bone scarred but intact.

"The new bone actually has comparable strength and mechanical properties to native bone," says Molly Stevens, currently a reader at Imperial College in the United Kingdom who did most of the research as a post-doctoral fellow at MIT, "and since the harvested bone is fresh it integrates really well at a recipient site."

Long bones in the body are covered by a thin outer layer called the periosteum. The layer is a little like scotch tape: the outside is tough and fibrous but the inside is covered with a layer of special pluripotent cells which, like marrow cells, are capable of transforming into the different types of skeletal tissue. So Shastri and his collaborators decided to create the bioreactor space just under this outer layer.

They created the space by making a tiny hole in the periosteum and injecting saline water underneath. This loosened the layer from the underlying bone and inflat
'"/>

Source:Vanderbilt University


Page: 1 2 3

Related biology news :

1. Color-blind method opens new doors in DNA sequencing
2. New imaging method gives early indication if brain cancer therapy is effective, U-M study shows
3. Studies reveal methods viruses use to sidestep immune system
4. An entropy-based gene selection method for cancer classification using microarray data
5. New methods of gene delivery using lasers
6. Breakthrough method in nanoparticle synthesis paves the way for new pharmaceutical and biomedical applications
7. Shift of weather patterns necessitates rethinking of reforestation methods
8. Scientists use manufacturing methods to reconstruct mastodon
9. Researchers develop promising new gene network analysis method
10. Researchers develop new method for facile identification of proteins in bacterial cells
11. A novel method to measure circadian cycles
Post Your Comments:
*Name:
*Comment:
*Email:
TAG: New method shows possible grow bone for grafts within patient body

(Date:9/18/2014)... team of researchers from McGill University and the ... of polyethylene ,microbeads, Canadian Journal of Fisheries ... originate from cosmetics, household cleansers, or industrial cleansers, ... Owing to their small size and buoyancy, they ... Microplastics are a global contaminant in the world,s ...
(Date:9/18/2014)... fall foliage season that prompts millions of Americans to undertake ... and possibly last a little longer within a century, according ... peeping in some areas of the United States as summer ... in the journal Global Ecology and Biogeography . For ... is the state tree of New Hampshire could change ...
(Date:9/18/2014)... researchers and their colleagues have built the first ... academic performance and behavioral trends. In other words, ... even if you don,t -- and how that ... students, happiness, stress, depression and loneliness to their ... general population for example, to monitor mental ...
Breaking Biology News(10 mins):Microplastic pollution discovered in St. Lawrence River sediments 2Fall foliage season may be later, but longer on warmer Earth 2Fall foliage season may be later, but longer on warmer Earth 3Fall foliage season may be later, but longer on warmer Earth 4New Dartmouth smartphone app reveals users' mental health, performance, behavior 2New Dartmouth smartphone app reveals users' mental health, performance, behavior 3New Dartmouth smartphone app reveals users' mental health, performance, behavior 4
... Rochelle, NY, January 29, 2009Two common strains of methicillin-resistant ... virtually eradicated in the laboratory by exposing them to ... photo-irradiation that is described in a paper published online ... . The article will appear in the April 2009 ...
... cases, sudden cardiac death (SCD) in young people is due ... by Silke Kauferstein of the Department of Forensic Medicine of ... the current Deutsches rzteblatt International ( Dtsch Arztebl ... defined as unexpected death occurring rapidlyusually within 1 h of ...
... discovered that a prototype drug reduces heart enlargement, one ... Heart failure, which occurs when the heart can,t ... people in the United States. The condition contributes to ... the laboratories of cardiologist and cell biologist Nipavan Chiamvimonvat, ...
Cached Biology News:Blue light destroys antibiotic-resistant staph infection 2UC Davis research shows that newly discovered drug reduces heart enlargement 2
(Date:9/19/2014)... 2014 Biotech companies make announcements ... drug systems and advanced Laboratory Instrumentation. Companies in focus ... BDX ), Thermo Fisher Scientific Inc. (NYSE: ... RGDO ), Sangamo Biosciences Inc. (NASDAQ: ... Pressure BioSciences, Inc. (OTCQB: PBIO) ("PBI" or the "Company") ...
(Date:9/19/2014)... Cereal grain scientists, quality regulators, ... October 5–8, 2014, for the AACC International (AACCI) ... in Providence, Rhode Island. The comprehensive scientific program ... scientists, chemists, microbiologists, nutritionists, and those interested in ... To date, 1,000 attendees have registered for the ...
(Date:9/18/2014)... Austin, TX (PRWEB) September 18, 2014 ... of integrated urological and interventional radiology products and ... (also known as cryotherapy and cryoablation) versus external ... Mid-Atlantic Section of the American Urological Association (MAAUA) ... , "Comparing Relative Effectiveness of Cryosurgery and ...
(Date:9/18/2014)... Ireland , September 18, 2014 ... and Markets ( http://www.researchandmarkets.com/research/czvg3s/biocompatible ) has ... "Biocompatible Materials - Global Strategic Business ... ,     (Logo: http://photos.prnewswire.com/prnh/20130307/600769) ,This report analyzes ... in US$ Million by the following ...
Breaking Biology Technology:Medical Instrumentation Automation Advances for Biological Sample Preparation - Company Expects Q4 Revenue Impact from Newest Instrument Systems 2Medical Instrumentation Automation Advances for Biological Sample Preparation - Company Expects Q4 Revenue Impact from Newest Instrument Systems 3Medical Instrumentation Automation Advances for Biological Sample Preparation - Company Expects Q4 Revenue Impact from Newest Instrument Systems 4Medical Instrumentation Automation Advances for Biological Sample Preparation - Company Expects Q4 Revenue Impact from Newest Instrument Systems 5Medical Instrumentation Automation Advances for Biological Sample Preparation - Company Expects Q4 Revenue Impact from Newest Instrument Systems 6Medical Instrumentation Automation Advances for Biological Sample Preparation - Company Expects Q4 Revenue Impact from Newest Instrument Systems 7Latest Research on Cereal Grain Quality, Health Benefits and Food Production to be Presented During the AACC International Annual Meeting 2Latest Research on Cereal Grain Quality, Health Benefits and Food Production to be Presented During the AACC International Annual Meeting 3HealthTronics Announces Data Comparing Cryotherapy Versus Radiation for Treating Prostate Cancer Poster Presented at the American Urological Association Regional Meeting 2Biocompatible Materials - Global Strategic Business Report 2014 2Biocompatible Materials - Global Strategic Business Report 2014 3
... device developed by the University of Wisconsin-Madison Lidar (Light Detection ... (Ice, Cloud and Land Elevation Satellite) laser device. ... chosen for the test because it operates on the same ... instrument to study the climate and changing polar ice sheets ...
... I first met up with the team at Qurb (pronounced ... world needed another anti-spam product. Not that the spam problem ... products and services in the market, it simply seemed an ... different. , ,I'd first met the founders in 1997 ...
... conditions provide a golden opportunity to tune your talent ... to have calmed, the long-term winners will be those ... strategies. Real competitive advantage comes from making a ... aligning your talent management practice to that choice, even ...
Cached Biology Technology:UW-Madison Laser Device to Study Polar Ice Caps 2Qurb Gets a Step Up From Second-Time Entrepreneurs 2Qurb Gets a Step Up From Second-Time Entrepreneurs 3Qurb Gets a Step Up From Second-Time Entrepreneurs 4Talent Constellations or Talent Communities Choosing the Right Talent 2Talent Constellations or Talent Communities Choosing the Right Talent 3
... The Gene Pulser Xcell microbial ... Hz, is used for electroporation of ... includes the main unit, PC module ... chamber, 10 sterile cuvettes (5 each ...
... Epithelial and endothelial cells-directed transfection ... RGD peptide-conjugated polyethylenimine which allows ... epithelial and endothelial cells. Integrins ... cell-cell and cell-matrix adhesion processes. ...
AVOID FREEZE/THAW CYCLES. Recognizes the ~5 kDa thymosin beta4 protein....
... Complete Solution Polymorphic DNA Technologies offers ... a complete solution for SNP discovery by ... oligonucleotide primers, PCR amplification, DNA sequencing and ... For SNP discovery, Polymorphic uses the gold ...
Biology Products: