Navigation Links
New insights into the software of life

A series of discoveries by an international consortium of scientists, including a team from The University of Queensland's Institute for Molecular Bioscience (IMB), will transform our understanding of how our genome works to produce a complex organism like a human being.

The findings of the consortium 'FANTOM', led by the Genomic Sciences Center, RIKEN Yokohama Institute and Genome Science Laboratory and RIKEN Wako Institute, will be published today in two papers in the prestigious journal Science.

Spokesman for the IMB team Professor David Hume, who has been a member of the FANTOM consortium for the past 5 years, and a senior author on both papers, said the massive data sets produced by the consortium, which were on the same scale as the completion of the human genome sequence, provided the scientific community with the tools to understand the control of protein production, truly the software of life.

"Genes provide the code for making the building blocks of our bodies - the proteins ?and the consortium has a made a massive step towards identifying all of those building blocks. But the genome must also contain the code to ensure that protein building blocks are made in the right place at the right time.

"The new data provides several indications of the molecular basis of evolution and why we are so much more complex than the simple worm, despite the fact that we only have a small number of additional conventional genes.

"In simple terms, the data shows that in mammals each individual gene uses multiple different mechanisms to produce different forms of protein. In a sense, each 'gene' is actually multiple different genes," Professor Hume explained.

The second of the papers in Science deals extensively with another area to which the IMB team has made a major contribution; outputs of the genome (RNAs) that do not code for protein.

IMB Director Professor John Mattick, co-author of these papers, has predicte d the importance of non-coding RNA in development and evolution in a series of papers published internationally over the past five years, including an article published in this same issue of Science entitled Functional genomics of non-coding RNA.

"I congratulate all IMB staff and students involved in this research collaboration, particularly David Hume who has been pivotal in developing the IMB's partnership with RIKEN over several years."

As part of the collaboration with RIKEN, Professor Hume's group has recently been awarded a grant from RIKEN to continue the translation of this work into the next phase, the Human Genome network project.


'"/>

Source:Research Australia


Related biology news :

1. New insights into how Huntingtons disease attacks the brain
2. Marsupial genome reveals insights into mammalian evolution
3. Frog’s ear canal may provide insights for understanding human hearing loss
4. New insights into neural tube defects
5. Engineered heart tissue offers insights into irregular heartbeats, defibrillator failure
6. AIDS vaccine research offers new insights on survival
7. Mutant mouse provides insights into breast cancer
8. From hot springs to rice farms, scientists reveal new insights into the secret lives of archaea
9. New insights into autoimmunity and depression
10. UWs Rosetta software to unlock secrets of many human proteins
11. GeneNotes - A novel information management software for biologists
Post Your Comments:
*Name:
*Comment:
*Email:


(Date:1/25/2016)...   Unisys Corporation (NYSE: UIS ) today announced ... International Airport, New York City , to help ... to enter the United States using passports ... pilot testing of the system at Dulles last year. The ... during January 2016. --> pilot testing of the ...
(Date:1/20/2016)... A market that just keeps on growing. Molecular Diagnostics ... genomics knowledge. Learn all about it in this new ... trends are pushing market growth and company valuations. Trends ... pathogen evolution - next generation sequencing - emergence of ... the role of genetic material in Disease and Health ...
(Date:1/13/2016)... , January 13, 2016 ... has published a new market report titled - Biometric Sensors ... and Forecast, 2015 - 2023. According to the report, the global ... and is anticipated to reach US$1,625.8 mn by 2023, ... 2023. In terms of volume, the biometric sensors market ...
Breaking Biology News(10 mins):
(Date:2/10/2016)... , Feb. 10, 2016 NX Prenatal Inc., ... proprietary NeXosome® technology for early warning of adverse ... most recent study by Dr. Thomas McElrath ... Society for Maternal Fetal Medicine,s (SMFM) annual meeting held ... th , 2016.  The presentation reported initial positive ...
(Date:2/10/2016)... New York, and New York, New York (PRWEB) , ... ... ... Regeneron Pharmaceuticals Inc. (NASDAQ: REGN) today announced that it ... and develop new vaccines and immunotherapies for infectious diseases and cancer. ...
(Date:2/10/2016)... 10, 2016  Allergan plc (NYSE: AGN ) ... Brent Saunders , Allergan,s CEO and President, will be ... session at the RBC Capital Markets Healthcare Conference on ... The New York Palace Hotel in New ... live and can be accessed on Allergan,s Investor Relations ...
(Date:2/10/2016)... ... February 10, 2016 , ... Benchmark ... today the promotion of two long-standing principal investigators (PI) to the roles of ... Research and Development. , Dr. Laurence Chu, a Benchmark Research PI in the ...
Breaking Biology Technology: