Navigation Links
New insights into the software of life

A series of discoveries by an international consortium of scientists, including a team from The University of Queensland's Institute for Molecular Bioscience (IMB), will transform our understanding of how our genome works to produce a complex organism like a human being.

The findings of the consortium 'FANTOM', led by the Genomic Sciences Center, RIKEN Yokohama Institute and Genome Science Laboratory and RIKEN Wako Institute, will be published today in two papers in the prestigious journal Science.

Spokesman for the IMB team Professor David Hume, who has been a member of the FANTOM consortium for the past 5 years, and a senior author on both papers, said the massive data sets produced by the consortium, which were on the same scale as the completion of the human genome sequence, provided the scientific community with the tools to understand the control of protein production, truly the software of life.

"Genes provide the code for making the building blocks of our bodies - the proteins ?and the consortium has a made a massive step towards identifying all of those building blocks. But the genome must also contain the code to ensure that protein building blocks are made in the right place at the right time.

"The new data provides several indications of the molecular basis of evolution and why we are so much more complex than the simple worm, despite the fact that we only have a small number of additional conventional genes.

"In simple terms, the data shows that in mammals each individual gene uses multiple different mechanisms to produce different forms of protein. In a sense, each 'gene' is actually multiple different genes," Professor Hume explained.

The second of the papers in Science deals extensively with another area to which the IMB team has made a major contribution; outputs of the genome (RNAs) that do not code for protein.

IMB Director Professor John Mattick, co-author of these papers, has predicte d the importance of non-coding RNA in development and evolution in a series of papers published internationally over the past five years, including an article published in this same issue of Science entitled Functional genomics of non-coding RNA.

"I congratulate all IMB staff and students involved in this research collaboration, particularly David Hume who has been pivotal in developing the IMB's partnership with RIKEN over several years."

As part of the collaboration with RIKEN, Professor Hume's group has recently been awarded a grant from RIKEN to continue the translation of this work into the next phase, the Human Genome network project.


'"/>

Source:Research Australia


Related biology news :

1. New insights into how Huntingtons disease attacks the brain
2. Marsupial genome reveals insights into mammalian evolution
3. Frog’s ear canal may provide insights for understanding human hearing loss
4. New insights into neural tube defects
5. Engineered heart tissue offers insights into irregular heartbeats, defibrillator failure
6. AIDS vaccine research offers new insights on survival
7. Mutant mouse provides insights into breast cancer
8. From hot springs to rice farms, scientists reveal new insights into the secret lives of archaea
9. New insights into autoimmunity and depression
10. UWs Rosetta software to unlock secrets of many human proteins
11. GeneNotes - A novel information management software for biologists
Post Your Comments:
*Name:
*Comment:
*Email:


(Date:4/4/2017)...   EyeLock LLC , a leader of iris-based ... Patent and Trademark Office (USPTO) has issued U.S. Patent ... an iris image with a face image acquired in ... 45 th issued patent. "The ... the multi-modal biometric capabilities that have recently come to ...
(Date:3/30/2017)... LOS ANGELES , March 30, 2017  On ... Hack the Genome hackathon at ... This exciting two-day competition will focus on developing health ... experience. Hack the Genome is ... has been tremendous. The world,s largest companies in the ...
(Date:3/30/2017)... -- Trends, opportunities and forecast in this market to ... AFIS, iris recognition, facial recognition, hand geometry, vein recognition, ... industry (government and law enforcement, commercial and retail, health ... and by region ( North America , ... , and the Rest of the World) ...
Breaking Biology News(10 mins):
(Date:10/12/2017)... ... 2017 , ... BioMedGPS announces expanded coverage of SmartTRAK Business ... US Hemostats & Sealants. , SmartTRAK’s US Market for Hemostats and Sealants module ... and biologic sealants used in surgical applications. BioMedGPS estimates the market will grow ...
(Date:10/11/2017)... (PRWEB) , ... October 11, 2017 , ... ... Foundation President Andi Purple announced Dr. Suneel I. Sheikh, the co-founder, CEO ... ASTER Labs ), Inc. has been selected for membership in ARCS Alumni ...
(Date:10/11/2017)... ... , ... ComplianceOnline’s Medical Device Summit is back for its 4th year. The ... Francisco, CA. The Summit brings together current and former FDA office bearers, regulators, industry ... officials from around the world to address key issues in device compliance, quality and ...
(Date:10/11/2017)... LAGUNA HILLS, Calif. , Oct. 11, 2017 ... London (ICR) and University of ... prognostic tool to risk-stratify patients with multiple myeloma (MM), in ... nine . The University of Leeds ... by Myeloma UK, and ICR will perform the testing services ...
Breaking Biology Technology: