Navigation Links
New gene linked to bipolar disorder

A new gene linked to both depression and bipolar disorder has been identified by UCL (University College London) and Danish researchers.

The collaboration, led by Professor Hugh Gurling at UCL and Professor Ole Mors at the University of Aarhus, first looked at bipolar cases in families living in the UK and in Denmark, and then at large numbers of unrelated people with bipolar disorder. The results of the genetic searches, published in the October issue of the American Journal of Psychiatry, identified the gene ?known as Slynar ?which is found on chromosome 12.

Bipolar disorder is known to run strongly in families, but the Slynar gene is one of just three genes now known to be implicated in susceptibility to the disorder. This gene appears to be present in around 10 per cent of bipolar disorder cases. Previous studies of families have already shown that there are multiple genetic subtypes of the disorder, but progress in identifying the exact genes responsible has been slow because groups of families inherit different susceptibility genes.

The Slynar gene is normally found in the brain, but in bipolar disorder has an abnormal effect due to mutations in the gene. However, researchers do not yet know what the gene's normal function is or how these mutations might be contributing to the disorder.

Professor Hugh Gurling, UCL Department of Mental Health Sciences, says: "The next step is to determine the role of the Slynar gene in the brain and how abnormalities in this gene may cause bipolar disorder. Using techniques such as animal models will help us to fully understand the mechanisms behind this gene and explore how we might be able to intervene in these mechanisms, to help people with the disorder.

"We hope our discovery will eventually lead to new treatments for depression and bipolar disorder, including possible preventive strategies, for example with drugs or even through nutritional intervention."

Around
'"/>

Source:University College London


Page: 1 2

Related biology news :

1. Newly discovered virus linked to childhood lung disorders and Kawasaki disease
2. Low level of extinction during ice age linked to adaptability
3. Improved statistical tools reveal many linked loci
4. Scientists at Galileo Pharmaceuticals confirm inflammatory response linked to glucose levels
5. Attacks of King George IIIs madness linked to key metabolism molecule
6. Gene controlling circadian rhythms linked to drug addiction
7. Physical and functional interaction of key cell growth molecules linked to cancer
8. VCU Massey Cancer Center study shows enzyme linked to spread of breast cancer cells
9. Naturally occurring asbestos linked to lung cancer
10. Disappearing arctic lakes linked to climate change
11. Genes linked to treatment resistance in children with leukemia
Post Your Comments:
*Name:
*Comment:
*Email:
TAG: New gene linked bipolar disorder

(Date:8/12/2015)... Aug. 12, 2015   MedNet Solutions , an ... spectrum of clinical research, is proud to announce that ... comprehensive SaaS-based eClinical technology platform, has led the way ... two quarters of 2015.   Q2 2015 and Q1 ... measured by contract value sold in the company,s 15 ...
(Date:8/11/2015)... August 11, 2015 Today, ZUK announced its ... as well as expected revenues in 2015 that relate to sales ... revenue guidance of approximately 2,200 MSEK for 2015. Jörgen ... prominent smartphone manufacturer in China ... selected FPC1 155 for Z1 ...
(Date:8/6/2015)... BOSTON and TELTOW, Germany ... the 2015 Siggraph Conference, SensoMotoric Instruments (SMI) ... augmented reality , based on Epson,s Moverio ... eye tracking platform. With this new solution, unprecedented quality ... multi-modal, hands-free interaction with context-sensitive displays. For the first ...
Breaking Biology News(10 mins):MedNet Solutions Experiences Explosive Corporate Growth 2FPC's Touch Fingerprint Sensor FPC1155 in ZUK's Smartphone Z1 2SMI Shows First Eye Tracking Upgrade for Augmented Reality Glasses 2SMI Shows First Eye Tracking Upgrade for Augmented Reality Glasses 3
... forecasting models are useful tools to help individuals and ... at risk from forest fire smoke, according to University ... shares his insight into the health impacts of smoke ... at the American Association for the Advancement of Science ...
... about neuroscience? How does melting permafrost impact the citizens ... cause energy use to spike and threaten Canada,s water ... and many other questions through presentations at the American ... the Vancouver Conference Centre Feb. 16 to 20 in ...
... Feb. 17, 2012  ChromaDex Corporation (OTCBB: CDXC), an ... solutions and ingredients to the dietary supplement, food ... of BluScience™ ( www.bluscience.com ), its ... that William F. Spengler has elected to step ...
Cached Biology News:As climate change increases forest fires, smoke forecasting could help protect public health 2UVic researchers among presenters at global science conference 2ChromaDex® Announces Management Changes 2ChromaDex® Announces Management Changes 3
(Date:8/28/2015)... ... August 28, 2015 , ... Proove Biosciences , a ... International Spine Intervention Society’ s 23rd Annual Scientific Meeting (ASM). The ASM ... a focus on evidence-based research and clinical application, the event gathered industry thought ...
(Date:8/28/2015)... /PRNewswire/ - RepliCel Life Sciences Inc. (OTCQB: REPCF) ... on the development of autologous cell therapies, today ... 30, 2015, corporate highlights, and near-term milestones.  The ... at www.sedar.com ,  www.edgar.com and ... expects to launch its RCS-01 treatment for aging ...
(Date:8/28/2015)... ... August 28, 2015 , ... Since the initial launch of FireflySci Inc. (FFS) in early ... excellent customer service. Images such as the Fonz in a lab coat and Large ... to the humdrum spectroscopy field. , FireflySci is proud to be the only ...
(Date:8/27/2015)... ... ... Capital Edge Consulting , a nationwide consulting firm that specializes in ... as one of the top 5000 companies listed on the 2015 Inc. 5000 ... “It is truly an honor to be recognized as one of America’s fastest growing ...
Breaking Biology Technology:Proove Biosciences Presents New Research Study at the International Spine Intervention Society’s Annual Scientific Meeting 2Proove Biosciences Presents New Research Study at the International Spine Intervention Society’s Annual Scientific Meeting 3Proove Biosciences Presents New Research Study at the International Spine Intervention Society’s Annual Scientific Meeting 4RepliCel Reports Second Quarter 2015 Financial Results 2RepliCel Reports Second Quarter 2015 Financial Results 3RepliCel Reports Second Quarter 2015 Financial Results 4RepliCel Reports Second Quarter 2015 Financial Results 5Cuvette Manufacturer FireflySci Launches Back to School Deals with Complimentary Shipping On All Orders 2Capital Edge Consulting Makes Inc. 5000 List of America’s Fastest-Growing Private Companies 2Capital Edge Consulting Makes Inc. 5000 List of America’s Fastest-Growing Private Companies 3
... Fazil Madison, Wis. - The 2006 winner ... has launched its first identity theft product, and has an ... three million customers after two years. , ,This probably sounds ... to reach positive cash flow, but consider the total market ...
... Wis. - Two more men have pleaded guilty ... a result of their selling nearly $6 million in ... eBay . , ,Assistant Attorney General Alice Fisher for ... the Eastern District of Wisconsin announced that ...
... - The United States Department of Energy ... three new Bioenergy Research Centers, including $125 million for a ... promote the development of cellulosic ethanol. , ,The Madison ... Great Lakes Bioenergy Research Center, will operate in collaboration with ...
Cached Biology Technology:Identity theft start up has fast-track growth plans 2Identity theft start up has fast-track growth plans 3Two convicted of selling $6 million in counterfeit Rockwell software on eBay 2UW-Madison to receive $125M for bioenergy research center 2UW-Madison to receive $125M for bioenergy research center 3
Template and primers for preparation of internal control spots...
Cross reactivity to St. Louis encephalitis (MSI-7) is determined by ELISA....
...
UV LAMP 254 NM 8 WATT, 1 EA. Category: Nucleid Acid Detection Systems....
Biology Products: