Navigation Links
New discovery blurs distinction between human cells and those of bacteria

ompartments have remained shrouded in mystery, largely because of an absence of a detailed understanding of their architecture, of what the structures look like," said Yeates, who also is a member of the California NanoSystems Institute and UCLA's Molecular Biology Institute. "The complete three-dimensional structure is still unknown, but in this paper we have provided the first three-dimensional structure of the building blocks of the carboxysome, a protein shell which is the best-studied microcompartment."

The UCLA biochemists also report 199 related proteins that presumably do similar things in 50 other bacteria, Yeates said.

"Our findings blur the distinction between eukaryotic cells and those of prokaryotes by arguing that bacterial cells are more complex than one would imagine, and that many of them have evolved sophisticated mechanisms," Yeates said.

While microcompartments have been directly observed in only a few organisms, "surely there will be many more," Yeates said. "The capacity to create subcellular compartments is very widespread across diverse microbes. We believe that many prokaryotes have the capacity to create subcellular compartments to organize their metabolic activities."

Yeates' research team includes research scientist and lead author Cheryl Kerfeld; Michael Sawaya, a research scientist with UCLA and the Howard Hughes Medical Institute; Shiho Tanaka, a former UCLA undergraduate who is starting graduate work at UCLA this fall in biochemistry; and UCLA chemistry and biochemistry graduate student Morgan Beeby.

The structure of the carboxysome shows a repeating pattern of six protein molecules packed closely together.

"We didn't know six would be the magic number," Yeates said. "What surprises me is how nearly these six protein molecules fill the space between them. If you take six pennies and place them in the shape of a ring, that leaves a large space in the middle. Yet the shape of this protein
'"/>

Source:University of California - Los Angeles


Page: 1 2 3

Related biology news :

1. Protein discovery could unlock the secret to better TB treatment
2. Purdue proves concept of using nano-materials for drug discovery
3. UCSD discovery may help extend life of natural pesticide
4. Leprosy microbes lead scientists to immune discovery
5. Biochemists report discovery of structure of major piece of telomerase; implications for cancer
6. Researchers make surprise discovery that some neurons can transmit three signals at once
7. Important discovery about second most fatal cancer
8. Harmless virus may hold key to more effective HIV drug discovery
9. Fundamental discovery -- Bone fracture
10. Genetic discovery could lead to drought-resistant plants
11. Gene discovery sheds light on causes of rare disease, cancer
Post Your Comments:
(Date:4/24/2014)... home from Iraq and Afghanistan, post-traumatic stress disorder (PTSD) ... and the culture at-large. Estimates indicate that as many ... Afghanistan suffer from PTSD. New research from the University ... on how PTSD is linked to other diseases in ... has implications beyond the impact of the psychiatric disorder ...
(Date:4/24/2014)... A common plant puts out a welcome mat to bacteria ... mix. , The study published this week in the ... targets during the battle between microbe and host that researchers ... the humble and oft-studied plant Arabidopsis puts out ... It,s as if a hostile army were unknowingly passing by ...
(Date:4/23/2014)... The greater prevalence of asthma, allergies and other chronic ... be due in part to their reduced exposure to ... a new scientific paper. , The article, published in ... that people living in urban centers who have less ... have chronic inflammation, a condition caused by immune system ...
Breaking Biology News(10 mins):New study links inflammation in those with PTSD to changes in microRNA 2New study links inflammation in those with PTSD to changes in microRNA 3How a plant beckons the bacteria that will do it harm 2How a plant beckons the bacteria that will do it harm 3Rural microbes could boost city dwellers' health 2Rural microbes could boost city dwellers' health 3
... into young adults, increasing time constraints due to school or work ... a study published in the January 2009 issue of the ... young adults enjoy and value time spent eating with others, 35% ... down and eat a meal. They further noted that "eating on ...
... 2009) - This month,s issue of Cold ... articles detailing experimental methods for the analysis of molecular ... proteins. Homologous recombination is an important mechanism for ... a Displacement Loop, or "D-loop," is formed as the ...
... Calif., January 5, 2009-- Scientists at Burnham Institute ... of the interactions between proteins that form the ... which is responsible for triggering apoptosis (programmed cell ... Ph.D., and colleagues, published online on Dec. 31 ...
Cached Biology News:Young adults need to make more time for healthy meals 2Methods for studying DNA repair and protein modification are featured in CSH Protocols 2Burnham researchers discover 'on switch' for cell death signaling mechanism 2
(Date:1/15/2014)... 15, 2014 DTS Language Services, Inc ... Web Portal for Life Science organizations who need document translations. ... subject matter of their documents in advance with a selection ... time-to-delivery of translations, often a critical factor in clinical and ...
(Date:1/15/2014)... Biotechnology Company, Limited ("TaiGen") today announced that they have ... pharmaceutical company, to develop and commercialize nemonoxacin (Taigexyn ® ... Turkey and other members of ... for the treatment of bacterial infections including those caused ...
(Date:1/14/2014)... 14, 2014  3D Communications, a leading provider of strategic communications services ... media events in the United States and ... Virginia Cox , JD, is returning to the firm,s ... re-joins 3D after more than two years of service as Associate ...
(Date:1/14/2014)... Md. , Jan. 14, 2014  Organovo announced today ... the National Institutes of Health (NIH) to help scientists ... treatments to patients on a faster timeline. Organovo is ... (NCATS) and the National Eye Institute (NEI) to develop ...
Breaking Biology Technology:DTS Improves Efficiency for Life Science Document Translations 2TaiGen Biotechnology Signed Exclusive License Agreement with R-Pharm for Nemonoxacin (Taigexyn(R)) 2TaiGen Biotechnology Signed Exclusive License Agreement with R-Pharm for Nemonoxacin (Taigexyn(R)) 3TaiGen Biotechnology Signed Exclusive License Agreement with R-Pharm for Nemonoxacin (Taigexyn(R)) 4Former FDA Associate Commissioner Returns To 3D Communications 2Organovo Announces Collaboration with National Institutes of Health 2Organovo Announces Collaboration with National Institutes of Health 3
... Receives NHPD/Health Canada Authorization to Begin a Study on, ... (Immunocal(R)) in, Combination with Physical Exercise on ... Levels in Elderly Persons: A Randomized, Double-Blind ... Inc. (TSX-V: IMM) announced today that the Natural Health Products ...
... the ninth consecutive year, internationally acclaimed celebrities will come ... http://starkeyhearingfoundation.org ), , the global leader in ... its mission of providing hearing instruments to underprivileged children ... will gather for the Foundation,s annual "So the World ...
... 7 OncoMed Pharmaceuticals, Inc., a clinical-stage company developing ... announced the appointment of Sunil Patel to the position ... new position, Mr. Patel will have primary responsibility for ... OncoMed,s President and Chief Executive Officer. , , ...
Cached Biology Technology:2009: Immunotec announces important clinical research initiative: New study to be launched with the goal of improving the quality of the aging process 22009: Immunotec announces important clinical research initiative: New study to be launched with the goal of improving the quality of the aging process 3Celebrities to Gather to Support the Ninth Annual Starkey Hearing Foundation 'So the World May Hear' Awards Gala 2Celebrities to Gather to Support the Ninth Annual Starkey Hearing Foundation 'So the World May Hear' Awards Gala 3OncoMed Pharmaceuticals Appoints Sunil Patel Senior Vice President, Corporate Development 2
Goat anti-VAV2 Class: Antibody Product Group: Miscellaneous Antibody...
Rabbit polyclonal to M13 Bacteriophage Coat Proteins ( Abpromise for all tested applications)....
E2F-5...
Rabbit polyclonal to Flagellin ( Abpromise for all tested applications). Antigen: Synthetic peptide from the flagellin C terminal domain of Burkholderia pseudomallei....
Biology Products: