Navigation Links
New complete muscle grown in the lab

A multinational team of researchers has grown new muscle complete with its own network of blood vessels in the laboratory, and implanted the new muscle in a living mouse. The accomplishment is a first for tissue engineering, according to a report in the June 19 issue of Nature Biotechnology.

Lead researcher Dr. Shulamit Levenberg of the Technion-Israel Institute of Technology, along with scientists from the Massachusetts Institute of Technology, grew the muscle from scratch by seeding a sponge-like, three-dimensional plastic scaffold with myoblasts and endothelial cells, which are the precursors to mature skeletal muscle and blood vessel cells. The researchers also added connective tissue cells called fibroblasts to the mix as a crucial third ingredient.

"The idea is that this hopefully will be used to repair or replace damaged muscle tissue when needed," Levenberg says.

In the near future, Levenberg explains, a simple muscle biopsy might provide the "seed" cells for a person's own engineered replacement muscle. For example, the lab-grown muscles could replace tissue lost to severe trauma such as burns, or build up muscle that has weakened or wasted away in diseases like AIDS.

Until now, most scientists have not attempted to provide engineered tissue with its own blood supply. Instead, they have implanted the new tissue into the body and waited for the body itself to infiltrate the tissue with blood vessels.

"Although this approach has been useful in many tissues, it has not been as successful in thick, highly vascularized tissues such as the muscle," Levenberg says.

To create muscle tissue that would be threaded through with blood vessels before being implanted, the researchers mixed different cell types together on the plastic mold for the tissue. The different cells quickly organized themselves on the scaffold, with the myoblast cells transforming into aligned and elongated muscle fiber tubes and the endothelial cell
'"/>

Source:ATS


Page: 1 2

Related biology news :

1. Whole genome fine map of rice completed
2. Worlds largest rainforest drying experiment completes first phase
3. Expression Project for Oncology (expO) completes first phase of standardized gene expression analyses
4. New design : complete
5. Sandia completes depleted uranium study
6. Illinois pig to make history as source of first complete swine genome
7. New findings offer more complete view of breast cancer gene mutations in US population
8. 2,000 influenza virus genomes now completed and publicly accessible
9. LIAI completes worlds most comprehensive analysis on influenza virus data
10. Heart repair gets new muscle
11. Small worm yields big clue on muscle receptor action
Post Your Comments:
*Name:
*Comment:
*Email:
TAG: New complete muscle grown the lab

(Date:8/20/2014)... could one day be made out of cocoa, rice ... reporting. The novel process they developed and their results, ... and plastic waste problems, appear in the ACS journal ... and colleagues at the Italian Institute of Technology point ... its production reached 288 million tons worldwide, but its ...
(Date:8/20/2014)... When a colony of honeybees grows to about 4,000 ... reproductive cycle: the building of a special type of ... team of experts from the Department of Neurobiology and ... what starts the reproductive cycle of honeybee colonies. The ... The Science of Nature . , Reproduction isn,t ...
(Date:8/20/2014)... and POINT ROBERTS, Washington , August 20, ... Key Role in Addressing Security Concerns in the Payment Industry? ... news source covering leading sectors including biometrics, issues commentary from ... Jason Peaslee , Managing Partner at Thrive Analytics, ... Gino Pereira , CEO of NXT-ID, Inc. (OTCBB: NXTD) ( ...
Breaking Biology News(10 mins):Worker bees 'know' when to invest in their reproductive future 2Digital Wallets for a Digital World - the Players and the Concerns for Consumer Adoption 2Digital Wallets for a Digital World - the Players and the Concerns for Consumer Adoption 3Digital Wallets for a Digital World - the Players and the Concerns for Consumer Adoption 4Digital Wallets for a Digital World - the Players and the Concerns for Consumer Adoption 5Digital Wallets for a Digital World - the Players and the Concerns for Consumer Adoption 6Digital Wallets for a Digital World - the Players and the Concerns for Consumer Adoption 7
... An in-depth study by Sandia National Laboratories and ... waste and dedicated energy crops could sustainably replace nearly ... The goal of the "90-Billion Gallon Biofuel ... large volume of cellulosic biofuel could be sustainably produced, ...
... that road salt used throughout the winter is making ... aquatic life and drinking water. The research indicates ... judicious use of road salt could help lessen the ... a video with research team leader Heinz Stefan, go ...
... elevations in Arizona,s Santa Catalina Mountains as summer temperatures ... Arizona in Tucson. The flowering ranges of 93 ... to where the same species flowered the previous ten ... the region increased about 1.8 degree Fahrenheit (1 degree ...
Cached Biology News:Biofuels can provide viable, sustainable solution to reducing petroleum dependence 2Biofuels can provide viable, sustainable solution to reducing petroleum dependence 3U of Minnesota research finds most road salt is making it into the state's lakes and rivers 2Plants take a hike as temperatures rise 2Plants take a hike as temperatures rise 3
(Date:8/20/2014)... August 20, 2014 The 6th ... being held on October 29-30 in San Francisco, CA. ... academic and government researchers and clinicians focused on addressing ... , In the twelve years since the sequencing ... have been introduced with pharmacogenetic information in the label ...
(Date:8/20/2014)... WriteResult®, a leading provider of Electronic Patient Outcome ... myPROpad™ ePRO tablet with the addition of a touchscreen ... widely used and well-respected Patient Reported Outcome (PRO) instruments ... used during clinical trials and in other health care ... to demonstrate Health-Related Quality of Life outcomes (HRQoL) resulting ...
(Date:8/19/2014)... Research and Markets  has announced the addition of the "Cell ... to their offering. This report analyzes the worldwide ... the following Product Segments: Media, Sera, and Reagents. The ... , Japan , Europe ... . Annual estimates and forecasts are provided for the period ...
(Date:8/19/2014)... (PRWEB) August 19, 2014 Robin Williams’ ... disease can take on an individual. Symptoms range ... facial expression, problems swallowing and severe depression. Parkinson’s ... dying off of dopamine producing neurons of the brain. ... a disease that slowly and progressively gets worse, they ...
Breaking Biology Technology:6th Annual Personalized and Precision Medicine Conference Bringing Together Thought Leaders to Discuss Clinical Implementation, Dx Reimbursement, Big Data, and Sequencing 2EQ-5D™ Assessment Now Available for iPad 2Global Cell and Tissue Culture Supplies - Strategic Business Report 2014 2As We Mourn Robin Williams’ Passing, His Death Sheds Light on Patients Struggling with Parkinson’s Disease 2As We Mourn Robin Williams’ Passing, His Death Sheds Light on Patients Struggling with Parkinson’s Disease 3
... Silence Therapeutics plc (AIM: SLN) ("Silence", the "Group" or ... company, today announces the appointment of Thomas Christély as ... based at Silence,s facility in Berlin. Thomas ... in corporate and business development and finance. He was ...
... researchers have developed a new technique to reach neurons ... and noninvasively. Up until now, scientists have thought that ... required. But in this new study, the Columbia Engineering ... can open the blood-brain barrierwith the added advantages of ...
... Korea, August 8, 2011Can a flexible LED conformably placed on ... human brain, or rolled upon the blood vessels, diagnose or ... in the near future. The team of Professor Keon ... developed a new concept: a biocompatible, flexible Gallium Nitride (GaN) ...
Cached Biology Technology:Appointment of Chief Executive Officer 2Appointment of Chief Executive Officer 3Appointment of Chief Executive Officer 4Engineers use short ultrasound pulses to reach neurons through blood-brain barrier 2
Mouse monoclonal [M7-PB-E9] to pan alpha Sodium Potassium ATPase ( Abpromise for all tested applications)....
Transcription factor Sp2. [Source:Uniprot/SWISSPROT;Acc:Q02086] Antigen: Recombinant Protein Epitope Signature Tag (PrEST)....
... [EP282Y] to Asparagine synthetase ( ... applications). Antigen: ... residues in the C-terminus of ... Entrez GeneID: 440 ...
Rabbit Anti-melatonin (different linkage) Polyclonal Antibody...
Biology Products: