Navigation Links
New clues to how sex evolves

rst we weren't sure they performed similar functions for the other chromosomes."

Dernburg and Phillips applied "reverse genetics" to the neighboring genes, obtaining worms from the Japanese National Bioresource in which each of the three new genes had been specifically deleted. By observing meiosis (and its failures) in these knock-out worms, it was clear that one of the new genes was responsible for successful pairing of the nonsex chromosomes II and III, one was responsible for pairing of chromosome V, and the third for chromosomes I and IV.

The researchers were able to visually detect the zinc-finger proteins during meiosis and show that each protein binds specifically to the chromosomes they help to pair. Further tracking showed that during meiosis the HIM-8 and ZIM proteins on each chromosome latch onto the cell's nuclear envelope. This activity is reminiscent of the way chromosomes attach to the nuclear envelope during meiosis in other organisms.

"In most eukaryotic species -- plants, mammals, fungi, and so on - the telomeres on the ends of the chromosomes anchor to the nuclear membrane in a transient structure called a 'meiotic bouquet,'" Dernburg says. "In C. elegans it's the Pairing Centers, not telomeres, that attach to the nuclear envelope. They do so seemingly randomly, not in a single bunch; nevertheless, the association with the nuclear envelope seems to serve a similar function, which is to stabilize chromosome interactions during pairing."

Exactly how, Dernburg says, is still unknown. "Zinc-finger proteins evolve rapidly because they are modular, so that combinations of elements allow them to move quickly to new binding sites on DNA, making the Pairing Centers of different chromosomes unique," she says. "Telomeres, on the other hand, are all very much alike, no matter which chromosome they're on. It could be that C. elegans, which is hermaphroditic and grows to maturity in only three days, is under a lot o
'"/>

Source:DOE/Lawrence Berkeley National Laboratory


Page: 1 2 3 4

Related biology news :

1. Insight into DNAs weakest links may yield clues to cancer biology
2. High-powered gene profiles provide clues to genes involved in common form of lung cancer
3. Genetic links could unlock clues to leading cause of blindness
4. ORNL, UC Berkeley unravel real-world clues to Earths mysteries
5. Elderly mice yield clues to the process of growing old
6. Engineered skin offers clues to melanoma development
7. Scientists uncover new clues about brain function in human behavior
8. On a wing and a prayer - Alaska researchers seek clues to bird flu
9. New clues to the dark side of a key anti-tumor guardian
10. Infection alarm yields clues to immune system behavior
11. Pair of studies offer new clues to combat antibiotic resistance
Post Your Comments:
*Name:
*Comment:
*Email:
TAG: New clues how sex evolves

(Date:12/19/2014)... , Dec. 18, 2014  23andMe, Inc., the leading ... study that pinpoints fine-scale differences in genetic ancestry of ... . Since immigrants first arrived more than ... has served as a meeting place for ... history and the ongoing mixing of peoples with African, ...
(Date:12/17/2014)... BELVOIR, Va. , Dec. 15, 2014 /PRNewswire-USNewswire/ ... efforts to make it easier to detect and ... chain. Today the agency started performing ... The capability will validate the authenticity of purchased ... chain. The new quality control measures will be ...
(Date:12/17/2014)... , Dec. 16, 2014 Research and ... the addition of the "Global Chemical Sensor ... http://photos.prnewswire.com/prnh/20130307/600769 ... the increasing demand for medical sensors in biomedical ... data for quick and correct diagnosis during surgical ...
Breaking Biology News(10 mins):23andMe Study Sketches Genetic Portrait of the United States 223andMe Study Sketches Genetic Portrait of the United States 323andMe Study Sketches Genetic Portrait of the United States 4Defense Logistics Agency Launches DNA Marking Capability to Strengthen Microcircuit Supply Chain 2Defense Logistics Agency Launches DNA Marking Capability to Strengthen Microcircuit Supply Chain 3Global Chemical Sensor Market 2015-2019: Key Vendors are Abbott Laboratories, Bayer, Hoffmann La-Roche, Johnson & Johnson, NGK Spark Plugs and Robert Bosch 2
... With the increasing popularity of whitening one,s teeth, ... of the University of Rochester Medical Center, set out ... tooth from using whitening products. Eastman Institute,s YanFang ... effects of 6 percent hydrogen peroxide, the common ingredient ...
... cellular backup of our brain. These cells are capable ... into neurons, astrocytes or oligodendrocytes. Astrocytes have supportive functions ... myelin layer around axons in order to accelerate neuronal ... know" which way it is supposed to develop? On ...
... will present societal awards to five distinguished ecologists at ... Albuquerque, New Mexico. More than 3,500 attendees are expected ... Steven Hubbell , Steven Hubbell of the University of ... will receive this year,s Eminent Ecologist Award, given to ...
Cached Biology News:OJ worse for teeth than whitening says Eastman Institute researchers 2Neural stem cell differentiation factor discovered 2Ecological Society of America announces 2009 award recipients 2Ecological Society of America announces 2009 award recipients 3
(Date:12/24/2014)... 23, 2014 SoundConnect’s ... designed to introduce cutting edge communication technology, ... partners of platform upgrades. This webinar series ... users in their quest to leverage web ... According to SoundConnect’s Marketing Manager, Seanna Baumgartner, ...
(Date:12/24/2014)... 2014 Nashville Fertility Center announced that ... for the American Society for Reproductive Medicine (ASRM), a ... in reproductive medicine. In his new role as ... executive board and will have a voice in furthering ... actively supported ASRM since 1984 when he joined while ...
(Date:12/24/2014)... Texas , Dec. 23, 2014 ... company focused on gynecologic disease, announced today that ... Schuler , Birchview Fund LLC and several Vermillion ... of unregistered shares of Vermillion,s common stock and ... stock in a private placement.  ...
(Date:12/24/2014)... NEW YORK , Dec. 23, 2014  NeuroLifeSciences ... of mazindol in children with attention deficit/hyperactivity disorder published ... 2014 . The paper, titled "Pilot ... deficit/hyperactivity disorder" ( Konofal et al, Drug ... 2014 ) shows that mazindol might be an ...
Breaking Biology Technology:SoundConnect Launches Leading Edge Business Communications Webinar Series 2SoundConnect Launches Leading Edge Business Communications Webinar Series 3Nashville Fertility Center Announces Dr. George A. Hill Selected to Serve as ASRM Treasurer for 2014-15 2Nashville Fertility Center Announces Dr. George A. Hill Selected to Serve as ASRM Treasurer for 2014-15 3Vermillion Announces Equity Financing of up to $18.9 Million; Suspends ATM Program 2Vermillion Announces Equity Financing of up to $18.9 Million; Suspends ATM Program 3Vermillion Announces Equity Financing of up to $18.9 Million; Suspends ATM Program 4Vermillion Announces Equity Financing of up to $18.9 Million; Suspends ATM Program 5Redefining ADHD: A New Approach & A Shift of Paradigm in ADHD Therapeutics 2Redefining ADHD: A New Approach & A Shift of Paradigm in ADHD Therapeutics 3
... January 22 Amsterdam Molecular,Therapeutics (Euronext: AMT), a leader ... Dr. Ronald H.W. Lorijn will for personal reasons retire,as ... van,Deventer, AMT,s chief scientific officer and co-founder of the ... basis. , Since Ronald Lorijn ...
... MichBio, the association for,Michigan,s biosciences industry, is ... Michigan Biosciences Directory and Resource Guide, the most,comprehensive ... and,organizations. The directory will be included in the ... spotlighting Michigan,biosciences news and trends. , ...
... NEW ROCHELLE, N.Y., Jan. 22 Biotechnology companies ... microfluidics techniques over the past decade and are ... in three years, reports Genetic Engineering and ... ). The technology offers a number of advantages, ...
Cached Biology Technology:AMT CEO Ronald Lorijn Steps Down 2AMT CEO Ronald Lorijn Steps Down 3MichBio Will Publish 2009 Michigan Biosciences Directory and Resource Guide 2GEN Reports on Growing Reliance on Microfluidics Technology 2
... The Z-Competent E. coli Transformation Buffer ... of competent E. coli cells for simple ... method completely eliminates the requirement for heat ... transformation can be performed by adding DNA ...
Request Info...
Buffer used for mitocapture assays....
... automated perfusion system. For real-time or ... biophysics, electrochemistry, or general liquid-handling research ... millisecond accuracy Run experiments automatically ... accuracy and flexibility Turnkey perfusion ...
Biology Products: