By providing vital information about brain function at the cot side, the scanner avoids the need to move critically ill babies to conventional scanning facilities, which may involve sedating them and has a degree of risk. The data produced by the new scanner can be used to diagnose and assess conditions such as brain haemorrhages and brain damage, and to inform decisions on effective treatment options.
A prototype of the scanner, called MONSTIR, has been developed by researchers at UCL (University College London) with funding from the Engineering and Physical Sciences Research Council (EPSRC) and the Wellcome Trust. Now, also with EPSRC funding, the team are aiming to reduce the size of the scanner and improve its speed of operation.
Currently, there are two main ways of performing brain scans on small babies. Magnetic resonance imaging (MRI) can provide data on brain function, but MRI scanners are large and static, and the baby may need to be sedated and wheeled to the scanner for the procedure to be carried out. The other alternative, ultrasound, can be performed at the cot side and is effective at revealing brain anatomy, but cannot show how the brain is actually functioning, e.g. in terms of oxygen supply and blood flow.
Combining the advantages of MRI and ultrasound but avoiding their disadvantages, MONSTIR, the first scanner of its kind in the world, uses an innovative technique called optical tomography to generate images showing how the brain is working. In optical tomography, light passes through body tissue and is then analysed by computer to provide information about the tissue.
A helmet incorporating 32 light detectors and 32 sources of completely safe, low-intensity laser light is placed on the baby's head. The sources produce short flashes and
Source:Engineering and Physical Sciences Research Council