Navigation Links
New brain hormone puts brakes on reproduction

icates via a blood portal with the anterior pituitary and stimulates production of the hormones gonadotropin, luteinizing hormone and follicle stimulating hormone.

These hormones are dumped into the bloodstream and make their way to the gonads, where in males they stimulate production of testosterone and the maturation of sperm. In females, the hormones stimulate production of estradiol, a sex steroid hormone and the body's main form of estrogen, and regulate ovulation, the production of fertile eggs.

Estradiol and testosterone, in turn, feed back on the pituitary to shut down production of pituitary hormones, establishing feedback that keeps the body's sex hormones on an even keel.

Estradiol also works higher in the brain, on the hypothalamus, to ramp down production of GnRH, but how this works has been a relative mystery. The new study provides an answer: Estradiol stimulates cells in the dorsomedial nucleus of the hypothalamus to produce GnIH, which appears to act directly on cells in the hypothalamus to turn off their production of GnRH.

"Here, we have a novel neural pathway mediating the regulatory actions of sex steroids," said Lance Kriegsfeld, UC Berkeley assistant professor of psychology.

"This is an example of the reproductive system being fine tuned," said George Bentley, UC Berkeley assistant professor of integrative biology. "We know a lot about the gross regulation of the reproductive system, but fine tuning hasn't been well understood at all."

GnIH was discovered five years ago in quail by Japanese researchers led by Kazuyoshi Tsutsui, a professor on the faculty of integrated arts and sciences at Hiroshima University. The discovery supplied one of the last remaining pieces of the bird's hormone system that controls reproduction. GnIH seemed to be the missing antagonist that switches off pituitary gonadotropins, and work by Tsutsui and Bentley in quail and white-crowned sparrows confirmed its role in turn
'"/>

Source:University of California - Berkeley


Page: 1 2 3 4

Related biology news :

1. Controversial drug shown to act on brain protein to cut alcohol use
2. Mouse brain cells rapidly recover after Alzheimers plaques are cleared
3. Mouse brain tumors mimic those in human genetic disorder
4. New imaging method gives early indication if brain cancer therapy is effective, U-M study shows
5. First atlas of key brain genes could speed research on cancer, neurological diseases
6. NYU study reveals how brains immune system fights viral encephalitis
7. Stem cells from brain transformed to produce insulin at Stanford
8. Birds brains reveal source of songs
9. Loves all in the brain: fMRI study shows strong, lateralized reward, not sex, drive
10. Revolutionary nanotechnology illuminates brain cells at work
11. A puzzle piece found in unraveling the wiring of the brain
Post Your Comments:
*Name:
*Comment:
*Email:
TAG: New brain hormone puts brakes reproduction

(Date:9/15/2014)... need for vitamin E and how much is enough, ... of this essential micronutrient are especially critical for the ... may become pregnant. , A lifelong proper intake of ... complicated by the fact that this nutrient is one ... It has been estimated that only a tiny fraction ...
(Date:9/12/2014)... , September 12, 2014 ... http://www.researchandmarkets.com/research/trs4c7/global ) has announced the addition of ... 2014" report to their offering. ,     ... Report 2014 is a professional and in-depth ... global fingerprint lock industry. , ,The report ...
(Date:9/12/2014)... of New York biologist Mike Hickerson, a team of international ... so many species of birds ended up in the Neotropics, ... the southernmost tip of South America. It is home to ... has beenhow did this extraordinary bird diversity originate?" said Dr. ... published in the journal Nature this week and ...
Breaking Biology News(10 mins):Vitamin E intake critical during 'the first 1,000 days' 2Vitamin E intake critical during 'the first 1,000 days' 3Global Fingerprint Lock Industry Report 2014 2
... of Biologists is pleased to announce BIOLOGY OPEN (BiO), ... research across all aspects of the biological sciences including ... journal aims to provide rapid publication for peer reviewed, ... fields. BIOLOGY OPEN will address some big issues ...
... a big effect on their life. Some people are ... which can be detrimental to their health and wellbeing. ... , A new study led by Dr Kathryn ... York has added important experimental evidence showing that animal ...
... fish, one from a Caribbean island and one from the Yucatan ... known in any organism, according to a new UC Davis study. ... Venezuela -- and they are all pretty much the same, said ... with Peter Wainwright, a professor of evolution and ecology at UC ...
Cached Biology News:Announcing BIOLOGY OPEN from the Company of Biologists 2Animals have personalities, too 2'Explosive' evolution in pupfish 2
(Date:9/15/2014)... interdisciplinary team of researchers led by Northeastern University ... precise inter-nanotube junctions and a variety of nanocarbon ... facile and easily scalable, which will allow the ... networks for use in applications ranging from electronic ... from cars to sports equipment. , Their findings ...
(Date:9/15/2014)... , Sept. 15, 2014  iVinci Health LLC, the ... Patient Revenue Management system, branded as VisitPay®, has successfully ... announced the launch of a new extension to VisitPay® ... an easy and convenient way for patients to manage ... owed by them and their families. The ...
(Date:9/15/2014)... CA (PRWEB) September 15, 2014 ... term implantable silicones for the medical device and ... silicone gel for the implantable medical device market. ... unique crosslink technology delivering a silicone gel with ... The Dual Matrix technology consists of two crosslinked ...
(Date:9/15/2014)... septiembre de 2014 La segunda anual International ... 12 al 18 de octubre. Como iniciativa conjunta de la ... compañías miembro s, la IPAW se ha diseñado para: ... a la colección de fuentes de plasma , Reconocimiento ... y mejorar las vidas , Aumento del conocimiento sobre ...
Breaking Biology Technology:Northeastern University Researchers Develop Novel Method for Working with Nanotubes 2iVinci Health Raises $5M to Fuel National Expansion, Announces Launch of Personal Finance Portal for Healthcare 2iVinci Health Raises $5M to Fuel National Expansion, Announces Launch of Personal Finance Portal for Healthcare 3Applied Silicone Launches Silicone Gel System with Dual Matrix Technology 2La International Plasma Awareness Week será una celebración para los donantes 2La International Plasma Awareness Week será una celebración para los donantes 3
... 2008 at 9:00 a.m. Eastern ... ... ALSE ) today reports operational and,financial results for the quarter ended ... http://www.newscom.com/cgi-bin/prnh/20080813/NEW056LOGO ), "We are encouraged by the progress we ...
... Named Contract Manufacturer of Choice, Based on Its ... Based on its recent,analysis of the pharmaceutical ... BioPharma Solutions (BPS) with the 2008 North,American Frost ... Award at,the 2008 Excellence in Healthcare Innovation Awards ...
... Novavax uses strategies to create vaccines for avian flu ... genetically-engineered virus-like particles (VLPs), ROCKVILLE, Md., ... today that its strategy for treating avian flu,through genetically-engineered ... at Cleveland Clinic 6th Annual Medical Innovation,Summit., Novavax, ...
Cached Biology Technology:Alseres Pharmaceuticals, Inc. Reports Third Quarter 2008 Operational and Financial Results 2Alseres Pharmaceuticals, Inc. Reports Third Quarter 2008 Operational and Financial Results 3Alseres Pharmaceuticals, Inc. Reports Third Quarter 2008 Operational and Financial Results 4Alseres Pharmaceuticals, Inc. Reports Third Quarter 2008 Operational and Financial Results 5Frost & Sullivan Awards Baxter's BioPharma Solutions Business the 2008 North American Customer Service Leadership of the Year Award 2Frost & Sullivan Awards Baxter's BioPharma Solutions Business the 2008 North American Customer Service Leadership of the Year Award 3Cleveland Clinic Recognizes New Strategies for Creating Vaccines for Avian Flu as a Top Ten Medical Innovation for 2009 2Cleveland Clinic Recognizes New Strategies for Creating Vaccines for Avian Flu as a Top Ten Medical Innovation for 2009 3Cleveland Clinic Recognizes New Strategies for Creating Vaccines for Avian Flu as a Top Ten Medical Innovation for 2009 4
... Single Cell Whole Genome Amplification Kit ... random fragmentation of genomic DNA and ... to PCR-amplifiable library molecules flanked by ... by PCR amplification of the library ...
Mouse monoclonal antibody to QARS - glutaminyl-tRNA synthetase...
Rabbit Anti-Mouse Ym1 Polyclonal Antibody,...
From formula-fed bovine calves Sterile, Cell culture tested...
Biology Products: