Navigation Links
New brain-chemistry differences found in depressed women

A new brain study finds major differences between women with serious depression and healthy women in a brain-chemical system that's crucial to stress and emotions.

The study adds further evidence that depression has its roots in specific alterations within the brain -- specifically in the endogenous opioid system that is a central part of the brain's natural pain and stress-reduction system. The findings also show significant variation between individuals with depression ?variation that seems to be linked to whether or not the patients respond to an antidepressant medication.

The study, performed by researchers at the University of Michigan Medical School affiliated with the U-M Depression Center, is published in the November issue of the Archives of General Psychiatry. It's based on brain imaging, blood chemistry and other data from 14 women with major depression, and 14 healthy women of about the same age and background. The women with depression were not taking antidepressants when the study began.

"This work gives further evidence of individual differences in brain mechanisms that are altered in major depression," says senior author Jon-Kar Zubieta, M.D., Ph.D., the Jenkins Research Professor of Depression and associate professor of psychiatry and radiology. "We found these differences in the response of the endogenous opioid system. Some women, but not others, with major depression, showed exaggerated responses in this system when undergoing an emotional challenge."

That emotional challenge was the summoning of memories of a very sad event in their lives, which the researchers asked the women to recall while they were lying in the positron emission tomography (PET) scanner having their brains imaged. The women recalled the death or serious illness of a friend or family member, a past divorce or breakup with a boyfriend, or other major difficulties. They also had their brains imaged during a neutral emotional state.


'"/>

Source:University of Michigan Health System


Page: 1 2 3

Related biology news :

1. Variation in womens X chromosomes may explain differences among individuals, between sexes
2. Big differences in duplicated DNA distinguish chimp and human genomes
3. Identical twins may have more differences than meet the eye
4. Study outlines genetic differences between potential pandemic influenza strains
5. Brain differences could explain why males and females experience pain relief differently
6. Most human-chimp differences due to gene regulation ?not genes
7. Albatross study shows regional differences in ocean contamination
8. Viral genetic differences are possible key to HIV dementia
9. Molecular differences between early and advanced melanomas could provide new drug targets
10. Analysis of rhesus monkey genome uncovers genetic differences with humans, chimps
11. Individual differences in a clock gene predict decline of performance during sleep deprivation
Post Your Comments:
*Name:
*Comment:
*Email:
TAG: New brain chemistry differences found depressed women

(Date:7/10/2014)... SPRINGS, Florida , July 1, 2014 ... wallets pave way for convenience and improved security: NXT-ID, Inc. ... Inc. (NASDAQ: GOOG ), Apple Inc. (NASDAQ: ... and MasterCard Corporation (NYSE: MA) NXT-ID, Inc., (OTCQB: NXTD) ... is pleased to announce that the second series of 30 ...
(Date:7/10/2014)... , July 3, 2014 Research and ... of the "Global Gesture Recognition & Touch-Less ... Forecasts to 2020" report to their offering ... Global Gesture Recognition & Touch-Less Sensing Market to ... for a while, but the companies were unable ...
(Date:7/10/2014)... , July 9, 2014 The widespread ... in large part by meaningful use and related ... providers interact with laboratory information. Now, more than ... field of clinical informatics in order to deliver ... To address the educational needs of pathologists in ...
Breaking Biology News(10 mins):Advantages for Digital Wallets Eliminate Need to Carry Credit Cards - Large Scale CNBC Ad Campaign for Latest Smart Wallet to Commence July 7th 2Advantages for Digital Wallets Eliminate Need to Carry Credit Cards - Large Scale CNBC Ad Campaign for Latest Smart Wallet to Commence July 7th 3Advantages for Digital Wallets Eliminate Need to Carry Credit Cards - Large Scale CNBC Ad Campaign for Latest Smart Wallet to Commence July 7th 4Advantages for Digital Wallets Eliminate Need to Carry Credit Cards - Large Scale CNBC Ad Campaign for Latest Smart Wallet to Commence July 7th 5Global Gesture Recognition & Touch-Less Sensing (2D, 3D, Ultrasonic, IR, Capacitive) Market - Forecasts to 2020 2New Clinical Informatics Curriculum Prepares Future Pathologists 2New Clinical Informatics Curriculum Prepares Future Pathologists 3New Clinical Informatics Curriculum Prepares Future Pathologists 4
... of Sheffield have applied an evolutionary ,use it or ... show that marriage can influence the evolution of age-patterns ... and Dr Andrew Russell, from the University,s Department of ... the 18th and 19th centuries, a time during which ...
... Using satellite data, scientists have produced a first-of-its kind map ... are other local- and regional-scale forest canopy maps, the new ... on one uniform method. The map, based on data ... scientists build an inventory of how much carbon the world,s ...
... University of California, Riverside biologists working on guppies ... long-term studies report that rapid growth responses to ... early in life have repercussions in adulthood. Based ... that grew rapidly as juveniles produced fewer offspring than ...
Cached Biology News:Marriage patterns drive fertility decline 2First-of-its-kind map details the height of the globe's forests 2Rapid growth in adolescence leads to fewer offspring, UC Riverside biologists find 2Rapid growth in adolescence leads to fewer offspring, UC Riverside biologists find 3
(Date:7/10/2014)... today in the journal PNAS (Proceedings of the ... of day and sleep deprivation have a significant effect ... looking at the best time of day to test ... for administering medicines effectively. , Researchers from the University ... investigated the links between sleep deprivation, body clock disruption ...
(Date:7/10/2014)... and spiders can sit upside down forever. Nanophysics makes sure ... in an article just published in Physical Review E ... Geckos and spiders that seem to be able to sit ... worldwide for many years. We will soon be able to ... the gecko,s foot. But the fact is, sooner or later ...
(Date:1/15/2014)... assembling a club sandwich at the nanoscale, National ... succeeded in crafting a uniform, multi-walled carbon-nanotube-based coating ... used in upholstered furniture and other soft furnishings. ... was reduced 35 percent compared with untreated foam. ...
(Date:1/15/2014)... Jan. 15, 2014   Niagara Thermal Products is ... Buffalo BioBlower Technologies LLC ("B3") as the critical thermal ... award from the Army Corps of Engineers.  B3 has ... all biological contaminants and destroys VOCs and other chemical ...
Breaking Biology Technology:Time of day crucial to accurately test for diseases, new research finds 2Even geckos can lose their grip 2Layered security: Carbon nanotubes promise improved flame-resistant coating 2Niagara Thermal Products LLC Selected as Critical Supplier for Buffalo BioBlower Air Purification Systems 2
... a leading waste-to-biofuels company, today held a groundbreaking ceremony ... waste-to-biofuels facility with its partners, the City of Edmonton ... Edmonton Mayor Stephen Mandel and Enerkem Chief Executive Officer ... advanced biofuels plant, which will be located in Edmonton, ...
... - Medicago Inc. (TSX: MDG), a clinical-stage biotechnology ... vaccines based on proprietary manufacturing technologies and Virus-Like ... in a report of President Obama,s Council of ... the President on Reengineering the Influenza Vaccine Production ...
... 31 /PRNewswire-FirstCall/ - Oncothyreon Inc. (Nasdaq: ... M. Eastland as Chief Financial Officer and Vice ... Eastland,s responsibilities will include financial management, investor relations ... more than 25 years of financial management experience ...
Cached Biology Technology:Enerkem Announces Construction Start of World's First Municipal Waste-to-Biofuels Facility in Edmonton, Alberta 2Enerkem Announces Construction Start of World's First Municipal Waste-to-Biofuels Facility in Edmonton, Alberta 3Medicago named in Presidential report on meeting the challenges of pandemic influenza 2Medicago named in Presidential report on meeting the challenges of pandemic influenza 3Medicago named in Presidential report on meeting the challenges of pandemic influenza 4ONCOTHYREON APPOINTS JULIE M. EASTLAND AS CHIEF FINANCIAL OFFICER 2
... The steadylite plus assay system ... assay sensitivity, Designed for batch-processing ... for higher density microplates such ... Odor free, Convenient storage conditions ...
... The versatile Promega Flipper® Racks are ... of your small tubes. These polypropylene racks ... choice for freezer storage. They may also ... Each rack is two-sided; one side accommodates ...
Sf9 cells derived from Spodoptera frugiperda ovarian cells (Sf21 cells) are commonly used to isolate and propagate recombinant AcMNPV viral stocks and to produce recombinant proteins....
...
Biology Products: