Navigation Links
New bacterium discovered -- related to cause of trench fever

s at the Massachusetts General Hospital of Harvard Medical School and the Centers for Disease Control and Prevention.

Before 1990, no Bartonella infections had been identified in the U.S. The new discovery is the sixth species identified that can infect humans, said Jane Koehler, MD, professor of infectious diseases at UCSF and senior author on the new paper.

Koehler encountered her first patient infected with Bartonella in 1987 during her first week of training in infectious diseases at the AIDS Clinic at San Francisco General Hospital Medical Center.

“The bacteria were eating away a bone in the arm of an AIDS patient – for months,” Koehler recalls. “They can cause extremely painful lesions and tumors of blood vessels on the skin of immunocompromised patients. But when I saw this patient, this type of infection had never been seen at UCSF, and the bacterium causing the infection was unknown.”

Koehler’s group went on to discover that two different Bartonella species can cause these disfiguring and potentially fatal infections in AIDS patients. Identification of the bacteria required laboratory studies of some of the microbes’ DNA sequences.

She was surprised to find that one of the microbes that causes severe infections in AIDS patients in the U.S was the same species that caused trench fever in WWI soldiers fighting in Europe 80 years before. The work was published in “The New England Journal of Medicine” in 1992.

Several years later, her team discovered that the Bartonella henselae bacterium causes cat scratch disease, an infection that causes swollen lymph nodes and fever after a cat scratches its owner or an unlucky visitor. They were again surprised to find that this microbe is the second Bartonella species to cause infection in AIDS patients.

Like trench fever, cat scratch disease had been described in the early 1900s, but no one knew what bacterium caused cat scratch disease until t
'"/>

Source:University of California - San Francisco


Page: 1 2 3 4

Related biology news :

1. Highly adaptable genome in gut bacterium key to intestinal health
2. Sequencing of marine bacterium will help study of cell communication
3. Researchers identify protein crucial for survival of Lyme-disease bacterium
4. Scientists reveal how disease bacterium survives inside immune system cell
5. Marine bacterium suspected to play role in global carbon and nitrogen cycles
6. Discovery that bacterium is phosphate gourmet key clue to what makes it most social of bacteria
7. How does Mycobacterium tuberculosis infect the lung?
8. How E. coli bacterium generates simplicity from complexity
9. Experimental TB drug effective against resistant and latent mycobacterium tuberculosis
10. Supersized island of resistance genes discovered in an infectious bacterium
11. Scientists discover a new disease-causing bacterium in an immune-compromised patient
Post Your Comments:
*Name:
*Comment:
*Email:
TAG: New bacterium discovered related cause trench fever

(Date:4/24/2014)... simple and cheap way of making a high-powered lens ... microscope. , Costing less than a cent, the lenses ... countries and remote areas. , The lens fabrication technique ... National University (ANU) Research School of Engineering, who collaborated ... Medical Research to find ways to transform the lentil-sized ...
(Date:4/24/2014)... University of North Carolina at Chapel Hill have developed ... plaque that is at high risk of breaking off ... is the plaque that builds up in arteries as ... meaning that they are more likely to detach from ... , "Existing state-of-the-art technologies are capable of determining if ...
(Date:4/24/2014)... plant puts out a welcome mat to bacteria seeking to ... The study published this week in the Proceedings of ... the battle between microbe and host that researchers can exploit ... and oft-studied plant Arabidopsis puts out a molecular ... if a hostile army were unknowingly passing by a castle, ...
Breaking Biology News(10 mins):Droplet lens 2New ultrasound device may add in detecting risk for heart attack, stroke 2How a plant beckons the bacteria that will do it harm 2How a plant beckons the bacteria that will do it harm 3
... Kofi Annan shared his hope with a gathering of ... of Commitment on HIV/AIDS would have heralded a response ... "significant but insufficient". , Citing achievements in the core ... of prevention programmes, and the availability of drug therapies, ...
... account for many cases of immune deficiency, in particular ... Common Variable Immunodeficiency (CVID), report researchers in the July ... a new diagnostic test for these conditions, which make ... because of a lack of good tests. , IgA ...
... voices they hear to the number of faces they ... finding indicates that numerical perception is truly an abstract ... sense, said the researchers. The experimental approach also will ... they have a verbal capacity, understand similar abstract numerical ...
Cached Biology News:Progress on HIV/AIDS significant but insufficient 2Progress on HIV/AIDS significant but insufficient 3Progress on HIV/AIDS significant but insufficient 4Gene for immune deficiency syndromes found 2Monkeys understand numbers across senses 2
(Date:1/15/2014)... 15, 2014 TaiGen Biotechnology Company, Limited ("TaiGen") today ... R-Pharm, a leading Russian pharmaceutical company, to develop and ... Russian Federation , Turkey ... is a novel antibiotic for the treatment of bacterial ...
(Date:1/14/2014)... Histogen, Inc., a regenerative medicine company ... under simulated embryonic conditions, today announced that they have ... Inc. for physician-dispensed aesthetic products containing Histogen’s proprietary multipotent ... is an amendment to the existing license between Histogen ...
(Date:1/14/2014)... January 14, 2014 EquitiesIQ, a leading ... (OTCQB: ALQA). Alliqua is an emerging biomedical company acquiring, ... wound care market. , Free report download: http://equitiesiq.com/reports/alliqua/ ... a seasoned management team and Board, which launched the ...
(Date:1/14/2014)... iLab Solutions, the leader in core facility ... of Product Strategy. In this role, Michelle will work with ... guide in the development of iLab products. Her main goal ... benefit to the scientific community by offering the most advanced, ...
Breaking Biology Technology:TaiGen Biotechnology Signed Exclusive License Agreement with R-Pharm for Nemonoxacin (Taigexyn(R)) 2TaiGen Biotechnology Signed Exclusive License Agreement with R-Pharm for Nemonoxacin (Taigexyn(R)) 3TaiGen Biotechnology Signed Exclusive License Agreement with R-Pharm for Nemonoxacin (Taigexyn(R)) 4Histogen and Suneva Medical Expand License for Cell Conditioned Media-based Aesthetic Products Internationally 2Histogen and Suneva Medical Expand License for Cell Conditioned Media-based Aesthetic Products Internationally 3EquitiesIQ Initiates Coverage of Alliqua, Inc. 2EquitiesIQ Initiates Coverage of Alliqua, Inc. 3iLab Solutions Announces Michelle Detwiler as the New Director of Product Strategy 2
... NASA,s Johnson Space Center,has awarded a five-year, ... Space Biomedical Research Institute, also known,as NSBRI, of ... Human,Research Program will continue biomedical research in support ... base period of the cooperative agreement began April ...
... BASEL, Switzerland and NUTLEY, N.J., Oct. 1 ... industry,s leading business and,marketing publications, selected Roche out ... the Year." This marks the first time Roche ... the company,s focus on innovation-driven,healthcare as demonstrated by ...
... ARBOR, Mich., Oct. 1 Assay Designs, Inc., a leading,provider ... translational research markets, announced two key additions to its,senior leadership ... company as Vice President, Research and ... Amgen in Thousand Oaks, CA, where he was ...
Cached Biology Technology:Med Ad News Honors Roche as 'Company of the Year' 2Med Ad News Honors Roche as 'Company of the Year' 3Assay Designs(TM) Announces Additions to the Leadership Team 2
... through the extracellular matrix (ECM) is an ... cells initiate invasion by adhering to and ... Proteolytic enzymes, such as MMP collagenases, dissolve ... membrane) surrounding the blood vessels to allow ...
... This CLS number is ... to easily match Cornings product ... yet, please order under the ... contact customer service for assistance. ...
Kit containing MACS equipment and reagents for immunopurification of proteins....
... of poor quality running into billions ... are under increasing pressure to reduce ... the microscopic distribution of ingredients is ... such as dissolution, stability, bio-availability and ...
Biology Products: