( w much longer they lived: if only a few...)New approach to BSE successful in lab

w much longer they lived: if only a few cells could produce siRNAs, the mice died at almost the same time as the control mice, i.e. on average after 170 days. However, if the majority of the brain cells were protected by siRNA, the mice survived the prion disease for up to 230 days, in other words about a third longer.

‘Basically siRNAs seem to be a promising therapeutic option for scrapie, CJD or BSE,?Professor Pfeifer emphasises. ‘However, it will take years before the method can be used on human beings.?The method is also relevant for animal breeding: in principle it can be used to breed cattle which cannot produce any PrP-C. They would then be resistant to BSE.
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Source:University of Bonn

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