Navigation Links
New antimicrobial compound adheres to skin to promote healing

University Georgia researchers have developed an anti-microbial treatment that adheres to the skin without being toxic.

Already, the treatment has helped heal Spirit, a burned dog in a high-profile animal cruelty case, and Gasper, a beluga whale at the Georgia Aquarium in Atlanta.

The researchers envision a human application for the technology, which they're currently seeking to patent.

Dr. Bran Ritchie, a distinguished research scientist in the department of small animal medicine and surgery at the UGA College of Veterinary Medicine, said the compound, known as Tricide, was initially developed by now retired UGA professor Dr. Richard Wooley to treat burns. It was later applied to skin lesions on fish and other aquatic animals. Tricide works by enhancing the effectiveness of antibiotics.

"In the case of burn victims, whether animal or human, bacteria and fungi can infect the open wounds and kill the patient," Ritchie said. "We have found a way to kill those drug-resistant bacteria and fungi with compounds that cleanse wounds while being gentle on the tissue."

Combining Tricide with a bioadhesive came about as a result of collaboration between Ritchie and Tony Capomacchia, an associate professor in the College of Pharmacy who specializes in the formulation of drug delivery systems.

The first noteworthy application of the Tricide bioadhesive came last year in the treatment of Spirit, the Athens-area dog that was deliberately set on fire. The researchers are currently using the compound to heal skin ulcers on a whale named Gasper who was rescued from a Mexico City amusement park and is now a popular resident of the Georgia Aquarium.

Petroleum-based ointments are commonly used in treating skin infections, but Capomacchia said that petroleum can be toxic and inhibit healing,"Using a petroleum product would be like pouring motor oil into the wound," he said.

Ritchie found that using an ointment made fr om vitamin E kept wounds from dehydrating and promoted healing. He learned that Capomacchia was also working with vitamin E in transdermal applications, and their collaboration began.

Ritchie said that the bioadhesive could have numerous human applications, particularly with swimmers or other athletes and people in military settings.

"In high-school athletics especially, getting staph infections from scratches is a huge problem. Our bioadhesive can adhere to wet skin, cleanse the wound and promote healing," he said, adding that they're also looking at a non-oily gel formulation for use as a combination cleanser and ointment for killing acne-causing bacteria.


'"/>

Source:University of Georgia


Related biology news :

1. Bacteria recognize antimicrobials, respond with counter-defenses
2. Researchers discover chemical compounds that affect plant growth
3. Bacterial genome sheds light on synthesizing cancer-fighting compounds
4. Scientists discover the bodys marijuana-like compounds are crucial for stress-induced pain relief
5. Evolution of taste receptor may have shaped human sensitivity to toxic compounds
6. Novel compounds show promise as safer, more potent insecticides
7. Metal-containing compounds show promise as HIV weapon
8. Natural compound from pond scum shows potential activity against Alzheimers
9. Chemical compound inhibits tumor growth, size in new mouse study
10. Seaweed yields new compounds with pharmaceutical potential
11. Phenolic compounds may explain Mediterranean diet benefits
Post Your Comments:
*Name:
*Comment:
*Email:


(Date:5/16/2016)... NEW YORK , May 16, 2016   ... authentication solutions, today announced the opening of an IoT ... to strengthen and expand the development of embedded ... provides an unprecedented level of convenience and security with ... to authenticate one,s identity aside from DNA. EyeLock,s platform ...
(Date:4/28/2016)... April 28, 2016 First quarter 2016:   ... 966% compared with the first quarter of 2015 The ... 589.1 M (loss: 18.8) and the operating margin was 40% (-13) ... Cash flow from operations was SEK 249.9 M (21.2) ... guidance is unchanged, SEK 7,000-8,500 M. The operating margin ...
(Date:4/15/2016)... -- Research and Markets has announced the ...  report to their offering.  ,      ... gait biometrics market is expected to grow at ... Gait analysis generates multiple variables such ... compute factors that are not or cannot be ...
Breaking Biology News(10 mins):
(Date:6/24/2016)... , June 24, 2016 Epic Sciences ... detects cancers susceptible to PARP inhibitors by targeting ... cells (CTCs). The new test has already been ... in multiple cancer types. Over 230 ... damage response pathways, including PARP, ATM, ATR, DNA-PK ...
(Date:6/23/2016)... , ... June 23, 2016 , ... ... release of its second eBook, “Clinical Trials Patient Recruitment and Retention Tips.” Partnering ... retention in this eBook by providing practical tips, tools, and strategies for clinical ...
(Date:6/23/2016)... June 23, 2016 /PRNewswire/ - FACIT has announced ... biotechnology company, Propellon Therapeutics Inc. ("Propellon" ... commercialization of a portfolio of first-in-class WDR5 inhibitors ... such as WDR5 represent an exciting class of ... precision medicine for cancer patients. Substantial advances have ...
(Date:6/23/2016)... Lawrence, MA (PRWEB) , ... June 23, 2016 ... ... the Peel Plate® YM (Yeast and Mold) microbial test has received AOAC Research ... test platform of microbial tests introduced last year,” stated Bob Salter, Vice President ...
Breaking Biology Technology: