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New antibody shows promise as cure for anthrax

e lab to find the animals still healthy and happy," Patterson said.

Upon examination of all the animals at the end of both experiments, scientists found no evidence of disease, with no or only trace amounts of anthrax residing in typical reservoirs for the bacteria, the lungs and spleen.

Iverson cautions it's not yet clear that this antibody treatment is as effective as the IgG antibody produced by Elusys, and that he and his collaborators are doing more studies to confirm that.

The researchers also plan to conduct additional tests to determine how the antitoxin eliminates anthrax bacteria, which is still unknown. They have two hypotheses, which might both be part of the full story. One hypothesis is that the antitoxin somehow neutralizes anthrax bacteria and prevents it from replicating. The other looks to innate immunity, theorizing that since the high-affinity antibody clears the body of the deadly toxin, it allows the body's initial immune response to successfully kill the anthrax bacteria on its own.


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Source:University of Texas at Austin


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