Navigation Links
New antibody shows promise as cure for anthrax

A new anthrax antibody engineered by scientists at The University of Texas at Austin protects and defends against inhalation anthrax without the use of antibiotics and other more expensive antibodies.

The high-affinity antibody, an anthrax antitoxin, successfully eliminated both anthrax bacteria and its deadly toxins in animal tests. If future tests concur, this could be the first successful treatment for late-stage anthrax infection, even for an anthrax strain that has been designed to resist antibiotics.

The new antibody treatment, reported in the December issue of Infection and Immunity, is the result of collaboration between the labs of Dr. Brent Iverson and Dr. George Georgiou at The University of Texas at Austin and a research team led by Dr. Jean Patterson at the Southwest Foundation for Biomedical Research (SFBR) in San Antonio.

"What we have found is that you may not even need the antibiotics to beat anthrax," says Iverson, professor of chemistry. He says that the new treatment "looks promising" and that it could lead to a simpler and cheaper way to treat anthrax. The new antibody is produced in bacterial cells, rather than the more expensive mammalian cell culture now used to produce anthrax antibodies.

Patterson, chair of the Department of Virology and Immunology at SFBR, adds, "A concern to national defense is that terrorists might design a strain of anthrax that is resistant to antibiotics, but this antitoxin could eliminate those concerns by providing an effective treatment that doesn't require antibiotics."

Anthrax infection is successfully treatable only in its early stages, when antibiotics can be used to kill anthrax bacteria. Before 2002, nothing was available to treat the large amounts of deadly toxin released by those bacteria, which is what leads to death in patients with late-stage anthrax infection.

In 2002, Iverson and Georgiou, a biomedical and chemical engineer, reported that their labs ha
'"/>

Source:University of Texas at Austin


Page: 1 2 3

Related biology news :

1. Secrets to antibodys success against West Nile Virus surprise scientists
2. Computer models aid understanding of antibody-dependent enhancement in spread of dengue fever
3. High resolution snapshots detail dynamics of a cocaine antibody
4. Buckyballs boost antibodys chemotherapy payload
5. Combination therapy with a monocloncal antibody and a vaccine leads to tumor rejection
6. A single sugar found responsible for an antibodys ability to treat inflammation
7. A key antibody, IgG, links cells capture and disposal of germs
8. Monoclonal antibody reduces exacerbations in asthmatics
9. Genome of deadly amoeba shows surprising complexity, evidence of lateral gene transfer
10. “Nano-scissors?laser shows precise surgical capability
11. Clam embryo study shows pollutant mixture adversely affects nerve cell development
Post Your Comments:
*Name:
*Comment:
*Email:
TAG: New antibody shows promise cure for anthrax

(Date:4/23/2014)... has transformed the energy landscape in the U.S., ... conflict among the energy industry, residents and agricultural ... add that degraded water quality is a potential ... article appears in the ACS journal Environmental ... and colleagues point out that a major criticism ...
(Date:4/23/2014)... the family of bacteria that causes whooping cough ... surprising findings about the bacteria,s origin and evolution. ... to control this respiratory disease, which kills 195,000 ... 343 strains of the Bordetella pertussis ... last 100 years illustrates how vaccination has shaped ...
(Date:4/23/2014)... quickly. It involves visual searching for clues to ... Similarly to humans, biological systems are sometimes under ... that need to be read quickly are usually ... easier it will be to read them quickly. ... Portugal) and Centre for Molecular and Structural Biomedicine ...
Breaking Biology News(10 mins):How to avoid water wars between 'fracking' industry and residents 2Impact of whooping cough vaccination revealed 2Cell division speed influences gene architecture 2
... is nicknamed "yellowcake" for its color and powdered consistency. ... , The yellow monster surfaced on the Navajo Nation ... continued for the next several decades. In its aftermath ... and worries about environmental contamination among people who live ...
... one day precisely release drugs and vaccines inside the ... study, by researchers at Ghent University and the Universit? ... Jan. 9, 2006, print issue of the American Chemical ... other microcapsules, which release their drug cargo only when ...
... study is being published in an advance online version of ... XPB helicase from an archaea, a single cell organism similar ... strands of the nucleic acid double helix, an action that ... well as other cell processes. , "XPB was initially ...
Cached Biology News:Study may help slay 'Yellow Monster' 2Study may help slay 'Yellow Monster' 3Enzyme crystal structure reveals 'unexpected' genome repair functions 2
(Date:1/14/2014)... (PRWEB) January 14, 2014 Date: Friday, April ... Location: Warrington Country Club, 1360 Almshouse Road, Warrington, Pa. ... nonprofit organization solely dedicated to finding a cure for hepatitis ... worldwide, will host its annual Crystal Ball on Friday, April ...
(Date:1/14/2014)... (PRWEB) January 14, 2014 EquitiesIQ, a ... Inc. (OTCQB: ALQA). Alliqua is an emerging biomedical company ... the wound care market. , Free report download: ... with a seasoned management team and Board, which launched ...
(Date:1/14/2014)... 2014  RXi Pharmaceuticals Corporation (OTCQX: RXII), a biotechnology ... therapies addressing major unmet medical needs using RNA-targeted ... of Allowance from the United States Patent and ... (sd-rxRNA®), for the treatment of fibrosis. The patent ...
(Date:1/14/2014)... During the 1600’s through the 1800’s doctors ... Plague.” In this time period, doctors did not know that ... to the death of vulnerable patients. In the same way, ... may be unwittingly transmitting herpes viruses to their patients. The ...
Breaking Biology Technology:Hepatitis B Foundation to Host Annual Crystal Ball Gala 2EquitiesIQ Initiates Coverage of Alliqua, Inc. 2EquitiesIQ Initiates Coverage of Alliqua, Inc. 3RXi Pharmaceuticals Receives US Notice of Allowance for a Key Patent Relating to its Self-Delivering Technology with sd-rxRNAs targeting CTGF, including RXI-109, for the Treatment of Fibrotic Disorders 2RXi Pharmaceuticals Receives US Notice of Allowance for a Key Patent Relating to its Self-Delivering Technology with sd-rxRNAs targeting CTGF, including RXI-109, for the Treatment of Fibrotic Disorders 3Study: Fatigued Medical Interns Infect Their Patients with Herpes Viruses; The CBCD Sees a Parallel with “The Doctor’s Plague” 2Study: Fatigued Medical Interns Infect Their Patients with Herpes Viruses; The CBCD Sees a Parallel with “The Doctor’s Plague” 3
... 21, 2009) A faster tool for cell programming and ... have won grand prizes of the 2009 Collegiate Inventors Competition, ... by the Abbott Fund, the non-profit foundation of the global ... Trademark Office (USPTO). Harris Wang, who invented a new ...
... Myriant Technologies LLC (Myriant), a privately-held, biotech developer ... of its Science Advisory Board and the appointment ... collectively will provide broad insight into all aspects ... biomass feedstocks into valuable chemicals. , (Logo: ...
... N.J. and WALTHAM, Mass., Oct. 21 BioWa, ... today that they have entered into an agreement ... POTELLIGENT(®) Technology platform for the development of antibody-dependent ... grants NKTT non-exclusive rights to research, develop, manufacture ...
Cached Biology Technology:Winners announced in 2009 Collegiate Inventors Competition 2Winners announced in 2009 Collegiate Inventors Competition 3Winners announced in 2009 Collegiate Inventors Competition 4Winners announced in 2009 Collegiate Inventors Competition 5Myriant Technologies LLC Announces Appointment of Science Advisory Board Members 2Myriant Technologies LLC Announces Appointment of Science Advisory Board Members 3BioWa and NKTT Announce Licensing of BioWa's POTELLIGENT(R) Technology For Use in Antibody Research and Development 2BioWa and NKTT Announce Licensing of BioWa's POTELLIGENT(R) Technology For Use in Antibody Research and Development 3