Navigation Links
Needling Chromosomes Reveals Cell Division Secret

By impaling individual chromosomes with glass needles one thousandth the diameter of a human hair, a Duke University graduate student has tested their "stickiness" to one another during cell division. Her uncanny surgical skills have added a piece to the large and intricate puzzle of how one cell divides into two -- a process fundamental to all organisms. In the Dec. 14, 2004, issue of Current Biology, Leocadia Paliulis and Bruce Nicklas report their progress in understanding how the pairs of chromosomes in each cell manage to balance their adhesion to one another and their release during cell division. Their work was sponsored by the National Institutes of Health. Chromosomes are the tiny fiber structures in the cell that house its genes. They replicate and separate in the process of cell division.

The exquisite management of adhesion properties between newly divided chromosomes, called chromatids, is crucial if the cells are to divide properly. In this process chromatids are drawn apart to separate poles of the dividing cell so that each new "daughter" cell contains a single copy of each. The same basic process operates in normal cell division, called mitosis, as well as the proliferation of sperm and egg cells called meiosis. "Chromosomes in mitosis and meiosis have to be held together, because otherwise they don’t attach to the apparatus called the spindle that distributes them to opposite poles," explained Nicklas, who is a Research Professor of Biology. "If they're held together, then one replicated chromatid can attach to one pole and the other to the opposite pole. But if they are not held together, they attach independently, and often both sister chromatids can go to the same pole rather than to opposite poles. This creates chromosome imbalances that can lead to cancer or chromosomal abnormalitiesthat cause birth defects." According to Nicklas, it was known that the two sister chromatids adhered to one another and released at the appropriate time dur
'"/>

Source:DUKE news


Page: 1 2 3

Related biology news :

1. NYU Study Reveals How Brains Immune System Fights Viral Encephalitis
2. Weill Cornell Research Reveals Secrets Of Trafficking Within Cells
3. Research Using Mouse Models Reveals A Novel Key Player In The Initiation Of Colon Cancer
4. Research Reveals Functions Of Harmful Shellfish Pathogens
5. Brain Scan Study of Smokers Reveals Signature of Craving
Post Your Comments:
*Name:
*Comment:
*Email:
TAG: Needling Chromosomes Reveals Cell Division Secret

(Date:7/24/2014)... how wildlife loss leads to conflict among people around ... Conservation Society (WCS) Health & Ecosystems: Analysis of Linkages ... interdisciplinary approach to tackle global biodiversity decline. , The ... the world,s people and provides protein for more than ... as no surprise that today,s unprecedented loss of wildlife, ...
(Date:7/24/2014)... -- The Geneva Healthcare Suite, an innovative technology platform ... room wait times by an average of 92 minutes ... to a recent study published in the Academic Emergency ... suite to access data from incoming patients, implanted cardiac ... Geneva,s technology platform we have been able to quickly ...
(Date:7/24/2014)... native animal species for food or commercial food sale, ... in the decline of many species of primates and ... more than half of the species being consumed are ... surveying not only the meat made available for sale ... forest by hunters and brought to villages for consumption, ...
Breaking Biology News(10 mins):New study draws links between wildlife loss and social conflicts 2UC San Diego Medical Center Cuts Average ER Wait Time by 92 Minutes using the Geneva Healthcare Suite 2UC San Diego Medical Center Cuts Average ER Wait Time by 92 Minutes using the Geneva Healthcare Suite 3
... plants is determined by pigments such as aurones, anthocyanins, ... displayed is dependent not only on the pigment present, ... of metal ions, and pH, among others. Information about ... plant geneticists to engineer new hues, adding to the ...
... hunted to local extinction more than a century ago and ... whales of mainland New Zealand are coming home. A ... that whales from a small surviving population around remote, sub-Antarctic ... mainland. Before the onslaught of 19th century whaling, historical ...
... Mary, University of London, sheds new light on why people ... suffer organ damage in parts of the body which are ... in Nature Immunology *, examines the way certain white ... defend damaged organs against injury or infection. This is ...
Cached Biology News:Engineering blue-hued flowers 2Fighting back from extinction, New Zealand right whale is returning home 2Fighting back from extinction, New Zealand right whale is returning home 3Rogue blood cells may contribute to post-surgery organ damage 2
(Date:7/24/2014)... July 24, 2014 Gain recognition ... Supply Chain of the biotech industry. Nominations are ... Awards, brought to you by the Bio ... of supply chain management professionals for the past ... stakeholders of the Biotech industry – Manufacturers, Service ...
(Date:7/24/2014)... forces worldwide rely on sophisticated equipment, trained personnel, ... public areas against terrorist attacks. A revolutionary new ... to make their job much easier. , The ... of Tel Aviv University ,s School of Chemistry ... by the Herzliya company Tracense, picks up the ...
(Date:7/24/2014)... natural and synthetic processes prefer to settle into ... energyit is within the realm of non-equilibrium conditions ... changes in energy and phases, such as temperature ... allow humans to regulate their body temperature, airplanes ... seismic activity. , But even though these ...
(Date:7/24/2014)... Calif. , July 24, 2014 SRI ... contract with the National Institute of Allergy and Infectious ... to conduct preclinical development of potential therapies for HIV ... drugs to treat HIV and AIDS and the complications ... as microbicides for preventing sexual transmission of HIV. ...
Breaking Biology Technology:Call for Submission: BSMA’s Supply Chain Management Innovation Awards 2Call for Submission: BSMA’s Supply Chain Management Innovation Awards 3Nano-sized chip 'sniffs out' explosives far better than trained dogs 2New approach to form non-equilibrium structures 2National Institute of Allergy and Infectious Diseases Awards SRI International Contract to Study New Therapies for HIV and AIDS 2National Institute of Allergy and Infectious Diseases Awards SRI International Contract to Study New Therapies for HIV and AIDS 3
... BASEL, Switzerland, April 17 Syngenta today,announced that it ... in,Beijing, China. Its focus will be on early-stage evaluation ... corn and soy, in the areas of yield,improvement, drought ... facility will have a global scope and will complement,Syngenta,s ...
... NexGenix Pharmaceuticals, presented,data on its Hsp90 inhibitor program ... San Diego today. The company presented data in ... novel, radicicol-based,Hsp90 inhibitors in its compound series., ... models,without evidence for liver and kidney toxicity. The ...
... Offers a Complete Solution for the Study of ... ... (Nasdaq:,SIAL) today announced the launch of its Imprint(TM) Chromatin,Immunoprecipitation Kit ... a complete,solution for Chromatin Immunoprecipitation, including columns and reagents,for DNA ...
Cached Biology Technology:Syngenta To Build Major Global Biotech Research Center in Beijing, China 2Syngenta To Build Major Global Biotech Research Center in Beijing, China 3NexGenix Pharmaceuticals Presents Data on a Novel Small Molecule Inhibitor of Heat Shock Protein 90 (Hsp90) at the Annual Meeting of the American Association for Cancer Research (AACR); Scientific Advisory Board Chairman Tyler Jacks Named President-elect 2NexGenix Pharmaceuticals Presents Data on a Novel Small Molecule Inhibitor of Heat Shock Protein 90 (Hsp90) at the Annual Meeting of the American Association for Cancer Research (AACR); Scientific Advisory Board Chairman Tyler Jacks Named President-elect 3Sigma(R) Launches Innovative ChIP Kit Technology For Epigenetic Research 2Sigma(R) Launches Innovative ChIP Kit Technology For Epigenetic Research 3
Contained in EZ-Tn5™ Kits and are available separately for sequencing of an insertion site....
Request Info...
Rabbit polyclonal to Syntrophin alpha 1 ( Abpromise for all tested applications). entrezGeneID: 6640 SwissProtID: Q13424...
Mouse monoclonal [4i97] to HLA Class 1 A25 ( Abpromise for all tested applications). Antigen: Full length protein (Human): HLA Class 1 Antigen-A25. Swiss Protein ID: P18462...
Biology Products: