Navigation Links
Nanowires can detect molecular signs of cancer, scientists find

ieber says, adding that the risk of false readings is minimized by the incorporation of various control nanowires.

The scientists also fitted some nanowires in the arrays with nucleic acid receptors for telomerase, an enzyme inactive in most of the body's somatic cells but active in at least 80 percent of known human cancers. In testing of extracts from as few as 10 tumor cells, these receptors allowed real-time monitoring of telomerase binding and activity.

Lieber says nanowire arrays could easily be scaled up to detect many different cancer markers -- more of which are being found all the time, thanks to the current boom in proteomics. Widespread use of these cancer markers in healthcare will ultimately depend upon the development of techniques that allow rapid detection of many markers with high selectivity and sensitivity.

"Genomics and proteomics research has elucidated many new biomarkers that have the potential to greatly improve disease diagnosis," the scientists write. "The availability of multiple biomarkers is believed to be especially important in the diagnosis of complex diseases like cancer, for which disease heterogeneity makes tests of single markers inadequate. Patterns of multiple cancer markers might, however, provide the information necessary for robust diagnosis of disease ?[and] detection of markers associated with different stages of disease pathogenesis could further facilitate early detection."

While initial rounds of cancer testing today identify only whether or not cancer is present, nanowire arrays have the potential to immediately fill in details on exactly what type of cancer is present. Nanowires could also track patients' health as treatment progresses. Because the arrays detect molecules suspended in fluids, drops of blood could be tested directly, in a physician's office, without any need for biochemical manipulation.

Lieber's co-authors are Gengfeng Zheng, Fernando Patolsky, Yi Cui and Wayne
'"/>

Source:Harvard University


Page: 1 2 3

Related biology news :

1. Novel technology detects human DNA mutations
2. Researchers find how protein allows insects to detect and respond to pheromones
3. Scientists detect probable genetic cause of some Parkinsons disease cases
4. Development of portable infectious disease detector
5. Novel ultrafast laser detection of cancer cells also may improve understanding of stem cells
6. Yale researchers identify molecule for detecting parasitic infection in humans
7. Robot-based system developed at Carnegie Mellon detects life in Chiles Atacama desert
8. Products containing specific probes for detecting alternative splice forms protected
9. Nanoparticles offer new hope for detection and treatment
10. Test for early detection of prostate cancer shows promise
11. Confocal imaging promises early detection of skin cancer
Post Your Comments:
(Date:12/13/2009)... Yale University researchers has used nanosensors to measure ... time. Their findings, which appear December 13 in ... , could dramatically simplify the way physicians test ... , The teamled by Mark Reed, Yale,s ... and Tarek Fahmy, an associate professor of biomedical ...
(Date:12/11/2009)... global "green" trend, educators worldwide are relying ... students, science knowledge. Studies have revealed that ... not just science scoresenvironmental-based lessons can also ... areas. Naturally, educators are interested in developing ... into the classroom in hopes of piquing ...
(Date:12/11/2009)... school children understand that green plants photosynthesize, absorb ... the profound global-scale effects that photosynthesis has had ... on the origins and evolution of photosynthesis is ... School of Life Sciences. , Oxygen, one of ... cyanobacteria and their descendants (including algae and higher ...
Breaking Biology News(10 mins):Scientists use nanosensors for first time to measure cancer biomarkers in blood 2Students learn environmental stewardship, improve science scores 2'Extreme' genes shed light on origins of photosynthesis 2'Extreme' genes shed light on origins of photosynthesis 3 Too Few Older Adults Get Recommended Screenings 61734 1 Too Few Older Adults Get Recommended Screenings 61734 2 Too Few Older Adults Get Recommended Screenings 61734 3Women can quit smoking and control weight gain 61732 1Women can quit smoking and control weight gain 61732 2Immunology expert at Childrens Hospital receives APS prize for patient oriented research 61730 1Immunology expert at Childrens Hospital receives APS prize for patient oriented research 61730 2
... soar, scientists at the National High Magnetic Field Laboratory ... enable petroleum companies to locate, analyze and process crude ... G. Marshall, a giant in the field of chemical ... agreement with a California-based company, Sierra Analytics ( www.MassSpec.com ...
... humans to plants to the lowliest bacterium use molecules ... an organism,s development, and still others are used to ... California Institute of Technology have now found a rare ... Caenorhabditis elegans that serves a dual purpose, working ...
... BIO-key International, Inc.,(OTC Bulletin Board: BKYI), a leader in ... announced that the,company,s Chief Executive Officer, Michael DePasquale, is ... The interview gives viewers an overview of the ... To view the clip in ...
Other Biology News:FSU, Magnet Lab researchers license critical petroleum data 2Caltech researchers find dual-use sexual attraction and population-control chemicals in nematodes 2Caltech researchers find dual-use sexual attraction and population-control chemicals in nematodes 3[video] Michael DePasquale, CEO of BIO-key International, Inc., Discusses Q2 2008 Revenue Growth on WallSt.net's 3-Minute Press Show 2
(Date:12/15/2009)... -- Thomson Reuters today ... the first drug pipeline database to fully integrate ... highly anticipated new content is being provided to ... ,, Thomson Pharma will offer drug ... releases, conferences, and other sources across all therapeutic ...
(Date:12/14/2009)... 14 Dyadic International, Inc. (Pink Sheets: ... its collaboration with The Scripps Research Institute ("Scripps") ... re-annotate the genome of Dyadic,s patented and proprietary ... continuation of the successful relationship between the two ... engaged Scripps to annotate the C1 genome for ...
(Date:12/14/2009)... Calif., Dec. 14 Nektar Therapeutics (Nasdaq: ... has been appointed to serve on its board ... industry leader with over 35 years of experience ... "Dennis brings to Nektar extensive industry perspective at ... Howard W. Robin, President and CEO of Nektar ...
(Date:12/11/2009)... Dendreon Corporation (Nasdaq: DNDN ) ... announced public offering have exercised in full their ... common stock at the public offering price of ... option increases the size of the offering to ... Dendreon expects to receive net proceeds from ...
Breaking Biology Technology:Thomson Reuters is First to Offer Fully Integrated Pipeline and Clinical Trials 2Dyadic International Extends Collaboration With The Scripps Research Institute 2Dyadic International Extends Collaboration With The Scripps Research Institute 3Dyadic International Extends Collaboration With The Scripps Research Institute 4Dyadic International Extends Collaboration With The Scripps Research Institute 5Dennis Winger Joins Nektar Therapeutics' Board of Directors 2Dennis Winger Joins Nektar Therapeutics' Board of Directors 3Dendreon Announces Exercise of Option by Underwriters in its Common Stock Offering 2Dendreon Announces Exercise of Option by Underwriters in its Common Stock Offering 3
... 29 ThermoGenesis,Corp. (Nasdaq: KOOL ), a ... stem cells, announced today it will report financial results,for ... Wednesday, February,4, 2009. , Company,s ... Management will host a conference call Wednesday, February 4, ...
... Inc. (Nasdaq: SNMX ) will release its financial ... 31, 2008 on Thursday, February 12, 2009 before the opening ... host a conference call and live Internet broadcast at 11:00 ... During the call, Senomyx,s management will provide a business ...
... the impact of one of the fastest growing eye diseases on ... provide physicians with a virtual experience of having neovascular (wet) age-related ... ... January 29, 2009 -- To help eye specialists better understand the ...
Other Biology Technology:ThermoGenesis Corp. to Announce Second Quarter Fiscal 2009 Results on February 4, 2009 2SENOMYX, INC. fourth quarter AND FISCAL YEAR-END 2008 Earnings conference call scheduled for February 12, 2009 2Looking at AMD Through Patients' Eyes: Viscira Virtual Exhibit Educates Physicians by Personalizing Serious Eye Disease 2Looking at AMD Through Patients' Eyes: Viscira Virtual Exhibit Educates Physicians by Personalizing Serious Eye Disease 3
... ClearSpin Filter is a novel disposable spin ... clarification of bacterial lysates in plasmid purification ... a novel, disposable spin filtration device especially ... lysates in plasmid purification procedures. The neutralized ...
... standard fixed-angle microcentrifuge rotor at RCF ... tube filters consist of a membrane-containing ... They filter by centrifugation for bacteria ... removal of cells from media and ...
... module C, 0.7 mm depth • Reusable, ... can be quickly assembled and disassembled for ... specimens of any thickness with up to ... three chambers per slide. Minimize specimen handling, ...
12 breakable polypropylene strips of 8 wells each held in a rigid frame. Ideal for antibody assays....
Biology Products: