Navigation Links
Nanotextured implant materials: blending in, not fighting back

most of the materials used in implants, which have microscale texture, but are nearly smooth at the nanoscale.

When the researchers changed the surface texture of implant materials to better match the natural texture of the endothelium, they found that endothelial cells quickly colonized the foreign surfaces, effectively camouflaging them and preventing smooth muscle cells from overgrowing the implants. Once the endothelial cells form a single, solid layer, they stop piling on and switch to producing the proteins collagen and elastin.

In one experiment, published with Purdue University graduate student Saba Choudhary in the journal Tissue Engineering, Webster and Haberstroh pressed together titanium particles that were less than 1 micron in size to create titanium with nanoscale surface texture. When they compared samples of the nanostructured material to conventional titanium in mixed cell culture, they found that the nanoscale surface features encouraged endothelial cells to colonize the material and spread much faster than smooth muscle cells. Where endothelial cells established themselves, they formed a single thin layer that inhibited overgrowth of the smooth muscle cells that tends to narrow stented arteries.

In another experiment, published in the Journal of Biomedical Materials Research with Purdue graduate student Derick Miller, the team molded pieces of PLGA, a biodegradable polymer often used for blood vessel grafts, so they came out completely covered with bumps that were 100, 200 or 500 nanometers in diameter. The surface with 200-nanometer features strongly favored the adsorption and spreading of fibronectin, a protein that helps endothelial cells quickly coat the graft.

Webster and Haberstroh's next step will be to test s
'"/>

Source:Brown University


Page: 1 2 3

Related biology news :

1. Ophthalmologists implant five patients with artificial silicon retina microchip
2. Polymers with copper show promise for implanted sensors
3. Engineers improve plastics potential for use in implants by linking it to biological material
4. Innovative coating could give medical implants a longer life
5. Magnetic probe successfully tracks implanted cells in cancer patients
6. Sooner is better with cochlear implants, Stanford scientist shows
7. Breast implants not associated with cancer risk, study reports
8. New implanted contacts designed to fix nearsightedness
9. With cochlear implants, earlier use leads to better speech
10. Protein-coated dental implants could improve bone regeneration
11. Nanotechnology being used to improve biocompatibility of human prosthetics and implants
Post Your Comments:
*Name:
*Comment:
*Email:
TAG: Nanotextured implant materials blending not fighting back

(Date:9/29/2014)... a new Food and Brand Lab pilot study, published ... in the National School Lunch Program (NSLP) by 9% ... , Chefs Move to Schools (CMTS), an initiative of ... in order to provide nutrition instruction to students and ... A CMTS event was held in an Upstate New ...
(Date:9/29/2014)... world,s needs to make cheaper and more effective ... efficient catalytic materials and processes must be developed. ... State University, is tackling this problem with the ... Science Foundation. , The nearly $1.5 million project, ... Cascade Reactions," was to Eranda Nikolla, Ph.D., assistant ...
(Date:9/29/2014)... five-year, $6 million grant for clinical research and ... of safe and effective treatments for cocaine addiction. ... Institutes of Health, National Institute on Drug Abuse, ... for Cocaine Use Disorder to oversee preclinical and ... moving forward with more expensive large-scale clinical trials. ...
Breaking Biology News(10 mins):Chefs move to schools can increase school meal participation and vegetable intake among students 2Wayne State research aims to develop new, more efficient catalytic materials 2New VCU center to target cocaine addiction 2
... Theres more to biofuels than the food vs. fuel debate ... And so Steven Fales, a professor of agronomy ... Iowa States Bioeconomy Institute, organized and moderated a three-hour symposium ... American Association for the Advancement of Science in Boston. ...
... theory into practice to manage complex and closely linked ... challenge, but one NOAA researcher Anne Guerry says can ... value of our ocean resources. Guerry will ... people obtain from ecosystems, in managing marine resources in ...
... This release is available in French . , ... the University of Toronto to rev up the production of stem ... cells and embryonic stem cells. The end products are blood and ... they form beating tissue. To do this, he has ...
Cached Biology News:Iowa Staters talk biofuels, healthy oils and 'pharma crops' at AAAS meeting 2Can Dungeness crab and eelgrass help improve management of our marine resources? 2From stem cells to organs: The bioengineering challenge 2
(Date:9/30/2014)... Jose, California (PRWEB) September 30, 2014 ... measure the level of each type of cholesterol carrier ... since the presence of excessive cholesterol levels in the ... a precursor condition to heart attack and other cardiovascular ... fatality worldwide, therefore testing for cholesterol levels on a ...
(Date:9/30/2014)... Hungary , September 30, 2014 ... and intuitive browsing of chemistry in documents ... chemistry software solutions and consulting services for life ... chemical information and generate Markush structures from documents. ... an organizations intellectual property, however generating and understanding ...
(Date:9/30/2014)... 30, 2014  KemPharm, Inc., a clinical-stage specialty ... of proprietary new molecular entity (NME) prodrugs, announced ... Office (USPTO) issued U.S. Patent No. 8,816,083 to ... Benzoic Acid Derivatives and Heteroaryl Carboxylic Acid Conjugates ... Thereof." The patent, which extends through ...
(Date:9/30/2014)... iLab Solutions announced the results of its ... on core facility operations, growth and utilization as well ... In its 4th year running, a number of long-term ... decrease in the percentage of revenue that comes from ... constraints of this trend. When asked, “What are your ...
Breaking Biology Technology:Surging Diabetic, Obese and Hypertensive Population Drives the Global Cholesterol Testing Market, According to New Report by Global Industry Analysts, Inc. 2Surging Diabetic, Obese and Hypertensive Population Drives the Global Cholesterol Testing Market, According to New Report by Global Industry Analysts, Inc. 3Surging Diabetic, Obese and Hypertensive Population Drives the Global Cholesterol Testing Market, According to New Report by Global Industry Analysts, Inc. 4ChemAxon Introduces ChemCurator for Chemical Information Extraction and Markush Structure Creation 2KemPharm, Inc. Receives Patent from the USPTO for Novel Prodrug of Hydromorphone, KP511 2iLab Solutions Announces the Results of the 2014 Core Facility Benchmarking Study 2iLab Solutions Announces the Results of the 2014 Core Facility Benchmarking Study 3
... ... ... ... keyed by longUrl, so we need to grab the first one. for (var r in data.results) { first_result = ...
... Technologies Business Unit Into New North American... -- SOUDERTON, Pennsylvania, October 13, 2010 ... ... --> ... s = ,; var first_result; // Results are keyed by longUrl, so we need to grab the ...
... Biopharma Leaders to Reveal Successful Strategies for China, India at the PharmAsia... -- SAN FRANCISCO, October 13, ... ... if (typeof(lpUnit)==,undefined,) var lpUnit=,PRN,; --> ... BitlyCB.alertResponse = function(data) { var s = ,; var first_result; // Results are keyed by longUrl, so ...
Cached Biology Technology:550 People Across Europe Will Die Today From a Preventable Lung Disease 2550 People Across Europe Will Die Today From a Preventable Lung Disease 3550 People Across Europe Will Die Today From a Preventable Lung Disease 4550 People Across Europe Will Die Today From a Preventable Lung Disease 5550 People Across Europe Will Die Today From a Preventable Lung Disease 6550 People Across Europe Will Die Today From a Preventable Lung Disease 7550 People Across Europe Will Die Today From a Preventable Lung Disease 8550 People Across Europe Will Die Today From a Preventable Lung Disease 9Almac Successfully Moves its Clinical Technologies Business Unit Into New North American Headquarters 2Almac Successfully Moves its Clinical Technologies Business Unit Into New North American Headquarters 3Almac Successfully Moves its Clinical Technologies Business Unit Into New North American Headquarters 4Almac Successfully Moves its Clinical Technologies Business Unit Into New North American Headquarters 5Almac Successfully Moves its Clinical Technologies Business Unit Into New North American Headquarters 6Almac Successfully Moves its Clinical Technologies Business Unit Into New North American Headquarters 7Almac Successfully Moves its Clinical Technologies Business Unit Into New North American Headquarters 8Biopharma Leaders to Reveal Successful Strategies for China, India at the PharmAsia Summit in San Francisco 2Biopharma Leaders to Reveal Successful Strategies for China, India at the PharmAsia Summit in San Francisco 3Biopharma Leaders to Reveal Successful Strategies for China, India at the PharmAsia Summit in San Francisco 4Biopharma Leaders to Reveal Successful Strategies for China, India at the PharmAsia Summit in San Francisco 5Biopharma Leaders to Reveal Successful Strategies for China, India at the PharmAsia Summit in San Francisco 6Biopharma Leaders to Reveal Successful Strategies for China, India at the PharmAsia Summit in San Francisco 7Biopharma Leaders to Reveal Successful Strategies for China, India at the PharmAsia Summit in San Francisco 8Biopharma Leaders to Reveal Successful Strategies for China, India at the PharmAsia Summit in San Francisco 9
Rabbit Anti-JNK1/SAPK pan, Polyclonal Antibody...
Low melting point. Ideally suited for in gel enzymatic reactions. Gelling temp. 24-28C Melting temp. 65C. EEO 0.12 Resolution 0.5-20 kb; Rnase/Dnase: none detected....
Rabbit polyclonal to XTP4 ( Abpromise for all tested applications). entrezGeneID: 84299 SwissProtID: Q9BRT3...
...
Biology Products: