Navigation Links
Nanotextured implant materials: blending in, not fighting back

most of the materials used in implants, which have microscale texture, but are nearly smooth at the nanoscale.

When the researchers changed the surface texture of implant materials to better match the natural texture of the endothelium, they found that endothelial cells quickly colonized the foreign surfaces, effectively camouflaging them and preventing smooth muscle cells from overgrowing the implants. Once the endothelial cells form a single, solid layer, they stop piling on and switch to producing the proteins collagen and elastin.

In one experiment, published with Purdue University graduate student Saba Choudhary in the journal Tissue Engineering, Webster and Haberstroh pressed together titanium particles that were less than 1 micron in size to create titanium with nanoscale surface texture. When they compared samples of the nanostructured material to conventional titanium in mixed cell culture, they found that the nanoscale surface features encouraged endothelial cells to colonize the material and spread much faster than smooth muscle cells. Where endothelial cells established themselves, they formed a single thin layer that inhibited overgrowth of the smooth muscle cells that tends to narrow stented arteries.

In another experiment, published in the Journal of Biomedical Materials Research with Purdue graduate student Derick Miller, the team molded pieces of PLGA, a biodegradable polymer often used for blood vessel grafts, so they came out completely covered with bumps that were 100, 200 or 500 nanometers in diameter. The surface with 200-nanometer features strongly favored the adsorption and spreading of fibronectin, a protein that helps endothelial cells quickly coat the graft.

Webster and Haberstroh's next step will be to test s
'"/>

Source:Brown University


Page: 1 2 3

Related biology news :

1. Ophthalmologists implant five patients with artificial silicon retina microchip
2. Polymers with copper show promise for implanted sensors
3. Engineers improve plastics potential for use in implants by linking it to biological material
4. Innovative coating could give medical implants a longer life
5. Magnetic probe successfully tracks implanted cells in cancer patients
6. Sooner is better with cochlear implants, Stanford scientist shows
7. Breast implants not associated with cancer risk, study reports
8. New implanted contacts designed to fix nearsightedness
9. With cochlear implants, earlier use leads to better speech
10. Protein-coated dental implants could improve bone regeneration
11. Nanotechnology being used to improve biocompatibility of human prosthetics and implants
Post Your Comments:
*Name:
*Comment:
*Email:
TAG: Nanotextured implant materials blending not fighting back

(Date:11/10/2014)... detergent pods began appearing on U.S. store shelves in ... numbers ever since. The small packets can be tossed ... out a liquid or powder. The convenience, though, has ... study from researchers at Nationwide Children,s Hospital found that ... reports of 17,230 children younger than 6 years of ...
(Date:11/7/2014)... Leading Biometric companies aim to provide ... online transactions.  Companies in focus today are: NXT-ID, Inc. (NASDAQ: ... BABA ), Google Inc. (NASDAQ: GOOG ), Microsoft ... EBAY ) and MasterCard Inc. (NYSE: MA) ... biometric authentication company focused on the growing mobile commerce is ...
(Date:11/6/2014)... an asset for a predator. Except when that predator runs ... beetle, relative to its size, is the fastest creature on ... lengths per second (at about five miles per hour). The ... the sprinting gold from the tiger beetle, a person would ... tiger beetle has a problem. At peak speeds, everything becomes ...
Breaking Biology News(10 mins):Study finds laundry detergent pods, serious poisoning risk for children 2Universal Authentication Methods Provide More Secure Operations for Biometrics Devices - Company Joins FIDO Alliance for Consumer Protection 2Universal Authentication Methods Provide More Secure Operations for Biometrics Devices - Company Joins FIDO Alliance for Consumer Protection 3Universal Authentication Methods Provide More Secure Operations for Biometrics Devices - Company Joins FIDO Alliance for Consumer Protection 4Universal Authentication Methods Provide More Secure Operations for Biometrics Devices - Company Joins FIDO Alliance for Consumer Protection 5Universal Authentication Methods Provide More Secure Operations for Biometrics Devices - Company Joins FIDO Alliance for Consumer Protection 6The tiger beetle: Too fast to see 2
... Cholesterol contributes to atherosclerosis a condition that greatly increases ... the activity of a key protein that protects the heart ... of Medicine have found. Their findings could lead ... the leading cause of death in the United States ...
... more than 50 years ago as a way to ... of Tennessee researcher to a significant finding about how ... conservation. In the middle of the 20th century, ... introduced a new species of salamander to California water ...
... produce cheap, sustainable solar energy by imitating nature. Nanotechnology ... are exploring nanoscale materials that mimic the architecture of ... energy. A new podcast looks at how ... to imbed tiny nanoparticles into simple, inexpensive everyday products ...
Cached Biology News:Research explains link between cholesterol and heart disease 2UT researcher sheds new light on hybrid animals 2UT researcher sheds new light on hybrid animals 3
(Date:11/22/2014)... Chicago, IL (PRWEB) November 21, 2014 ... technology competitors at the 2014 Emerging Medical Technologies Summit ... MedTech Innovator Awards. Widely regarded among Silicon Valley ... emerging medical device innovation, the win also positions Briteseed ... the MedTech Innovator competition in 2015 and compete with ...
(Date:11/22/2014)... Rapids, MI (PRWEB) November 22, 2014 ... opportunity to simulate the proper management of life-like ... and test lung devices . Grand Rapids-based, Michigan ... plans to donate two of the respiratory simulation ... to $15,000 each. Grand Valley and Muskegon Community ...
(Date:11/22/2014)... , November 21, 2014 ... wechselt als Chief Commercial Officer zu KLOX    ... der Unternehmensentwicklung und Chief Financial Officer bestellt    ... mit der Vermarktung seines jüngst zugelassenen Behandlungssystems zur Wundheilung ... ("KLOX" bzw. das "Unternehmen") ist sehr erfreut, die folgenden ...
(Date:11/21/2014)... --  TRU-D SmartUVC LLC and its UK partners, Rapid ... robot, TRU-D SmartUVC, at FIS 2014 in Harrogate, ... at Stand 23. The conference, hosted by Federation ... largest infection-related event of its kind and brings together ... leading events of its type throughout the world. This annual ...
Breaking Biology Technology:Insight Product Development Accelerator Member Wins MedTech Innovator Award Competition 2Insight Product Development Accelerator Member Wins MedTech Innovator Award Competition 3Michigan Instruments Donates Two Respiratory Simulation Training and Test Lung (TTL) Devices to Grand Valley State University 2Michigan Instruments Donates Two Respiratory Simulation Training and Test Lung (TTL) Devices to Grand Valley State University 3KLOX Technologies meldet Neubesetzung von Führungspositionen 2KLOX Technologies meldet Neubesetzung von Führungspositionen 3KLOX Technologies meldet Neubesetzung von Führungspositionen 4KLOX Technologies meldet Neubesetzung von Führungspositionen 5TRU-D SmartUVC to Showcase Superbug-Killing Robot at FIS 2014 2TRU-D SmartUVC to Showcase Superbug-Killing Robot at FIS 2014 3
... New England Biolabs has expanded its line of PCR ... Hot Start DNA Polymerases. Optimized blends of Taq ... offer robust amplification across a wide range of templates, including ... Deep Vent increases the fidelity and robustness of Taq ...
... PARK, N.C., Feb. 14, 2011 India,s premier ... Neurological Society of India & Congress of Neurological ... December.  The event was a convergence of leading ... from across the globe to discuss advances made ...
... Va., Feb. 14, 2011 Technology Catalysts International (TCI), ... research on trends and development in drug delivery have ... drugs with limited patent life, a different pathway for ... product a competitive edge in a crowded pharmaceutical field. ...
Cached Biology Technology:New England Biolabs Introduces OneTaq™ DNA Polymerase, a Robust Solution for Routine and Difficult PCR 2Max Neeman International Initiates Advisory Committee to Advance and Improve the Conduct of Complex Neurological Trials in India 2Parenteral Depots Offer $8 Billion of Reformulation Opportunities and a Strong Competitive Edge in Crowded Pharmaceutical Space 2
... expression vectors, we in-troduced a new concept, namely ... tran-scriptional level at the T7 phage promoter, and ... the plasmid copy number, The main advantage of ... practically all of the outstanding features of the ...
... Anti Nop1p/Fibrillarin (monoclonal) Nop1p/Fibrillarin ... protein of bakers yeast, Saccharomyces cerevisiae ... essential for yeast viability and is ... homologue of Nop1p is fibrillarin (accession ...
... protein crystallography involves using many of the ... The liquid handling requirements are similar to ... crystallography plates have 24 or 48 wells ... For higher throughput, the number of wells ...
... The Reverse-iT™ One-Step Kit is the ... in RT-PCR. It has been specifically ... The Reverse-iT™ One-Step Kit combines ... and ABgene®s Thermoprime Plus DNA Polymerase ...
Biology Products: