Navigation Links
Nanotechnology to provide portable genetic risk detection

Currently being developed by the IST project OPTONANOGEN, a prototype of the system will initially be used to detect mutations of the BRCA1 gene that are responsible for between 2.5 and 5 per cent of the incidence of breast cancer in women. The final system, however, could be used to detect virtually any genetic anomaly as well as proteins linked to viruses, chemical contamination in food or water pollution.

"There are a broad variety of applications for this system, although the main market is in biomedicine," explains OPTONANOGEN coordinator Laura Lechuga at the National Microelectronics Centre (CNM) in Spain. "Though commercial biosensing systems exist they are larger and designed to be used in laboratories. We are the first to develop a fully integrated system on a small scale in this field."

The final device will be roughly the size of a human hand, allowing it to be used in doctors' surgeries to determine the genetic predisposition of a patient to certain diseases in a matter of minutes. That compares to the hours or even days it can take to carry out the same analysis in a laboratory, which is generally only used to test high risk groups such as women with a family history of breast cancer.

To detect genetic mutations the OPTONANOGEN system uses an array of 20 microcantilevers coated in nucleic acid that react when they come into contact with a DNA sample displaying the genetic anomaly. The sample is injected into the device via a microfluidic header and the deflection of the cantilevers ?by as little as 0.1 to 0.5 nanometres ?is picked up by a photodetector array based on the reflection of light off the cantilevers from Vertical Cavity Surface Emission Lasers (VCSELs).

"We've patented both the microcantilever set up and the optical detection system and we are due to take out a third patent on the microfluidic header, which is unique in that it uses individual inlet and outlet paths for each cantilever rather than one for the wh
'"/>

Source:IST Results


Page: 1 2

Related biology news :

1. Nanotechnology may find disease before it starts
2. Nanotechnology being used to improve biocompatibility of human prosthetics and implants
3. Nanotechnology propels advances in regenerative medicine research
4. Nanotechnology shows promise as next wrinkle fighter
5. Nanotechnology meets biology and DNA finds its groove
6. Experiments provide proof of how traveling in groups protects insects
7. Experiments provide proof of how traveling in groups protects insects
8. ASU researchers finds novel chemistry at work to provide parrots vibrant red colors
9. MetaChip provides quick, efficient toxicity screening of potential drugs
10. Alaskan puzzles, monitoring provide insight about North Pacific salmon runs
11. NYU and MSKCC research provides model for understanding chemically induced cancer initiation
Post Your Comments:
*Name:
*Comment:
*Email:
TAG: Nanotechnology provide portable genetic risk detection

(Date:5/7/2015)... Fingerprint Cards (FPC) introduces ... FPC,s smallest touch fingerprint sensors to date.  ... integration on the backside of the phone, and ... to integrate touch fingerprint sensors in the OEMs, ... for module manufacturers to customize the look and ...
(Date:4/27/2015)... , Apr. 27, 2015 NXT-ID, Inc. ... biometric authentication company focused on the growing mobile commerce ... shipping to pre-order customers the first week of May, ... the month of May. Gino ... significant milestone for the company as Wocket® enters the ...
(Date:4/20/2015)... 2015 The announcement comes as ... Records Management (GRM), Ireland,s foremost records ... Having built up an impressive track record of clients within ... within the records management sector in Dubai ... GCC staffbase and employ a further eight staff members at ...
Breaking Biology News(10 mins):FPC Introduces its Smallest Touch Fingerprint Sensors to Date 2Wocket, the Smartest Wallet You Will Ever Own, Announces Shipment to Pre-order Customers 2Wocket, the Smartest Wallet You Will Ever Own, Announces Shipment to Pre-order Customers 3Glenbeigh Records Management Wins Contract With Dubai Islamic Bank 2Glenbeigh Records Management Wins Contract With Dubai Islamic Bank 3
... DNA repair gene may be an early step in the ... basis for this inactivation may ultimately be useful in risk ... the September 21 issue of the Journal of the ... region of cells with a "field defect", cells that appear ...
... Skeletal muscles naturally repair themselves very efficiently after ... following damage from overuse during exercise, surgery or ... muscle repair slows noticeably, and in Duchenne Muscular ... functions can't cope with disease progression. , Researchers ...
... aren't able to swat a fly? The fly's secret in ... jump rather than to fly out of the way. "This ... building autonomously navigating robots", according to Gwyneth Card of the ... on triggered escape response at the Society for Experimental Biology ...
Cached Biology News:Change in gene may be underlying molecular defect in some colorectal cancers 2Muscle repair: Making a good system better, faster; implications for aging, disease 2Muscle repair: Making a good system better, faster; implications for aging, disease 3Muscle repair: Making a good system better, faster; implications for aging, disease 4
(Date:5/20/2015)... 2015 Agricultural firm H.J. Baker & ... acquisition of Tiger-Sul. Since the purchase of Tiger ... in May 2005, H.J. Baker has leveraged the innovation ... a comprehensive portfolio of product offerings and solutions expertise. ... and the innovation of Tiger-Sul, transforming the company into ...
(Date:5/20/2015)... SAN DIEGO , May 20, 2015 /PRNewswire/ ... today announced a collaboration with Celgene Corporation to ... novel genomic biomarkers that associate with patient response ... collaboration is intended to help accelerate patient access ... increasing efficiencies in clinical research and development and ...
(Date:5/20/2015)... , 20. Mai 2015 /PRNewswire/ ... klinische Logistik (Clinical Logistics Organization/CLO) hat ... 2014, das am 31. Dezember 2014 ... hat die Marktentwicklung übertroffen und sein ... http://photos.prnewswire.com/prnh/20110930/NY78064LOGO ...
(Date:5/20/2015)... DENVER , May 20, 2015 /PRNewswire/ ... today announced that it is an official ... Management Executives (CHIME) Cooperative Members Services Program. ... of compliant, managed cloud services and best ... of healthcare CIOs and service providers, enabling ...
Breaking Biology Technology:Agricultural Firm H.J. Baker & Bro., Inc., Celebrates 10 Years Since Acquisition Of Tiger-Sul 2Agricultural Firm H.J. Baker & Bro., Inc., Celebrates 10 Years Since Acquisition Of Tiger-Sul 3Cypher Genomics Collaborates with Celgene Corporation to Identify Novel Genomic Biomarkers 2Marken schließt Ergebnisse für das Geschäftsjahr 2014 ab 2HOSTING Named Partner of the CHIME Cooperative Member Services Program 2HOSTING Named Partner of the CHIME Cooperative Member Services Program 3
... ... Europe, Canada, and Russia requiring confidential, direct buyer representation for a ... Board Certified real estate attorney and Lic. Real Estate Broker, Christian ... broker and real estate attorney exclusively for premium property buyers, greatly ...
... It is an amazing sight: What looks like a tiny ... barely the size of a fingernail, floating in a Petri ... , Researchers at The University of Arizona,s Sarver Heart ... (SAVAHCS) have come a step closer to repairing hearts damaged ...
... technique to record three-dimensional movies of microscopic systems, such ... is reported in Optics Express , has potential ... technique, developed in the laboratory of NYU Physics Professor ... recording the images of microscopic systems and then analyzing ...
Cached Biology Technology:Miami Beach Real Estate Attorney Opens Miami Real Estate Brokerage for International Luxury Miami Beach Condo Buyers From Distressed Sellers 2Miami Beach Real Estate Attorney Opens Miami Real Estate Brokerage for International Luxury Miami Beach Condo Buyers From Distressed Sellers 3Heart disease: Research off the beating patch 2NYU physicists find way to explore microscopic systems through holographic video 2NYU physicists find way to explore microscopic systems through holographic video 3
...
p21 Ras Immunogen: Recombinant C-H-ras p21(val-12). Storage: 4 C...
Rabbit polyclonal to Myosin VIIa (rating: *****) ( Abpromise for all tested applications). entrezGeneID: 4647 SwissProtID: Q13402...
Rabbit polyclonal to GPCR G2A ( Abpromise for all tested applications). entrezGeneID: 29933 SwissProtID: Q9UNW8...
Biology Products: