Navigation Links
Nanotechnology to provide portable genetic risk detection

Currently being developed by the IST project OPTONANOGEN, a prototype of the system will initially be used to detect mutations of the BRCA1 gene that are responsible for between 2.5 and 5 per cent of the incidence of breast cancer in women. The final system, however, could be used to detect virtually any genetic anomaly as well as proteins linked to viruses, chemical contamination in food or water pollution.

"There are a broad variety of applications for this system, although the main market is in biomedicine," explains OPTONANOGEN coordinator Laura Lechuga at the National Microelectronics Centre (CNM) in Spain. "Though commercial biosensing systems exist they are larger and designed to be used in laboratories. We are the first to develop a fully integrated system on a small scale in this field."

The final device will be roughly the size of a human hand, allowing it to be used in doctors' surgeries to determine the genetic predisposition of a patient to certain diseases in a matter of minutes. That compares to the hours or even days it can take to carry out the same analysis in a laboratory, which is generally only used to test high risk groups such as women with a family history of breast cancer.

To detect genetic mutations the OPTONANOGEN system uses an array of 20 microcantilevers coated in nucleic acid that react when they come into contact with a DNA sample displaying the genetic anomaly. The sample is injected into the device via a microfluidic header and the deflection of the cantilevers ?by as little as 0.1 to 0.5 nanometres ?is picked up by a photodetector array based on the reflection of light off the cantilevers from Vertical Cavity Surface Emission Lasers (VCSELs).

"We've patented both the microcantilever set up and the optical detection system and we are due to take out a third patent on the microfluidic header, which is unique in that it uses individual inlet and outlet paths for each cantilever rather than one for the wh
'"/>

Source:IST Results


Page: 1 2

Related biology news :

1. Nanotechnology may find disease before it starts
2. Nanotechnology being used to improve biocompatibility of human prosthetics and implants
3. Nanotechnology propels advances in regenerative medicine research
4. Nanotechnology shows promise as next wrinkle fighter
5. Nanotechnology meets biology and DNA finds its groove
6. Experiments provide proof of how traveling in groups protects insects
7. Experiments provide proof of how traveling in groups protects insects
8. ASU researchers finds novel chemistry at work to provide parrots vibrant red colors
9. MetaChip provides quick, efficient toxicity screening of potential drugs
10. Alaskan puzzles, monitoring provide insight about North Pacific salmon runs
11. NYU and MSKCC research provides model for understanding chemically induced cancer initiation
Post Your Comments:
*Name:
*Comment:
*Email:
TAG: Nanotechnology provide portable genetic risk detection

(Date:9/18/2014)... system that can operate inside the bore of an ... a biomedical research partnership program at Brigham and Women,s ... the robot, in conjunction with real-time MRI images, can ... and less discomforting for the patient. The novel system ... with greater precision. , Developed by a team of ...
(Date:9/18/2014)... the International Space Station ever starts a "frequent flyers" ... status. Recently the orbiting laboratory has hosted increasing numbers ... returned from the space station in April, and another ... third experiment is planned to launch in December. , ... around the world-- and in space. Model organisms can ...
(Date:9/18/2014)... that prompts millions of Americans to undertake jaunts into the ... a little longer within a century, according to new research. ... areas of the United States as summer temperatures linger later ... Global Ecology and Biogeography . For instance, the paper ... tree of New Hampshire could change color one to ...
Breaking Biology News(10 mins):Trial begins for MRI-compatible robot designed to improve accuracy of prostate biopsies 2Trial begins for MRI-compatible robot designed to improve accuracy of prostate biopsies 3Trial begins for MRI-compatible robot designed to improve accuracy of prostate biopsies 4Trial begins for MRI-compatible robot designed to improve accuracy of prostate biopsies 5Buzzing with activity: Fruit flies orbit Earth for science 2Buzzing with activity: Fruit flies orbit Earth for science 3Buzzing with activity: Fruit flies orbit Earth for science 4Fall foliage season may be later, but longer on warmer Earth 2Fall foliage season may be later, but longer on warmer Earth 3Fall foliage season may be later, but longer on warmer Earth 4
... generation of "green" automobile tires that can boost fuel efficiency ... the research pipeline. The new tires could help add an ... economy. That,s the topic of the cover story of the ... newsmagazine. C&EN Senior Editor Alexander Tullo explains that ...
... causing fatal and infectious diseases of the nervous system, ... sheep or Creutzfeldt-Jakob disease in humans. Scientists of Helmholtz ... in elucidating another disease mechanism of prion diseases: The ... quantities of cholesterol. Prions need this for their propagation. ...
... Rochelle, NY, November 18, 2009Quantitative polymerase chain reaction ... and rapid expansion as a result of advances ... wells and optimization-free multiplexing, reports Genetic Engineering & ... detect and simultaneously quantify specific DNA sequences is ...
Cached Biology News:The protein Srebp2 drives cholesterol formation in prion-infected neuronal cells 2
(Date:9/18/2014)... Ireland , September 18, 2014 ... and Markets ( http://www.researchandmarkets.com/research/czvg3s/biocompatible ) has ... "Biocompatible Materials - Global Strategic Business ... ,     (Logo: http://photos.prnewswire.com/prnh/20130307/600769) ,This report analyzes ... in US$ Million by the following ...
(Date:9/18/2014)... , Sept. 18, 2014 Research ... "Global and Chinese Stem Cell Industry Report, 2014-2017" ... cells are undifferentiated biological cells that can differentiate into ... more stem cells. Stem cell therapy can be applied ... hematological system disease), nervous system diseases, damage or lesion ...
(Date:9/18/2014)... Research and Markets has announced the addition ... In-situ hybridization, Immunohistochemistry) Market - Trends & Forecasts to ... The global companion diagnostics market is expected to grow ... Factors such as rising need for personalized medicine in ... pharmaceutical industry, support from regulatory authorities, and emerging technologies ...
(Date:9/18/2014)...  MEI Pharma, Inc. (Nasdaq: MEIP ), an ... for cancer, announced today that Daniel P. Gold , ... NewsMakers in the Biotech Industry conference on Friday, ... Millennium Broadway Hotel & Conference Center in New ... be accessed at www.meipharma.com . A replay will be ...
Breaking Biology Technology:Biocompatible Materials - Global Strategic Business Report 2014 2Biocompatible Materials - Global Strategic Business Report 2014 3Global and Chinese Stem Cell Industry Report, 2014-2017 2Global and Chinese Stem Cell Industry Report, 2014-2017 3Global Companion Diagnostics (Polymerase Chain Reaction, In-situ hybridization, Immunohistochemistry) Market - Trends & Forecasts to 2019 2Global Companion Diagnostics (Polymerase Chain Reaction, In-situ hybridization, Immunohistochemistry) Market - Trends & Forecasts to 2019 3MEI Pharma To Present At BioCentury's NewsMakers Conference 2MEI Pharma To Present At BioCentury's NewsMakers Conference 3
... Amnis Corporation, a manufacturer of advanced cell imaging systems, ... Millipore, the Life Science division of Merck KGaA of Germany. ... expected to take place in the fourth quarter of 2011. ... Amnis generated sales of USD 14 million (EUR 10 ...
... infect cells is crucial to preventing countless human diseases. ... Bristol have discovered a new approach for studying molecules ... the complexity of how bacteria infect people. The ... physicists and published in the Proceedings of the ...
... 2011 /PRNewswire-Asia-FirstCall/ -- China Cord Blood Corporation (NYSE: ... cord blood collection, laboratory testing, hematopoietic stem cell processing, and ... results for the first quarter of fiscal year 2012, which ... Quarter of Fiscal 2012Highlights ...
Cached Biology Technology:Amnis Acquired by EMD Millipore - Expands Growth Potential 2Amnis Acquired by EMD Millipore - Expands Growth Potential 3Scientists develop new technologies for understanding bacterial infections 2Scientists develop new technologies for understanding bacterial infections 3China Cord Blood Corporation Reports Financial Results for the First Quarter of Fiscal 2012 2China Cord Blood Corporation Reports Financial Results for the First Quarter of Fiscal 2012 3China Cord Blood Corporation Reports Financial Results for the First Quarter of Fiscal 2012 4China Cord Blood Corporation Reports Financial Results for the First Quarter of Fiscal 2012 5China Cord Blood Corporation Reports Financial Results for the First Quarter of Fiscal 2012 6China Cord Blood Corporation Reports Financial Results for the First Quarter of Fiscal 2012 7China Cord Blood Corporation Reports Financial Results for the First Quarter of Fiscal 2012 8China Cord Blood Corporation Reports Financial Results for the First Quarter of Fiscal 2012 9China Cord Blood Corporation Reports Financial Results for the First Quarter of Fiscal 2012 10
ANTI 5-HYDROXYTRYPTOPHAN CONJ....
IMAGEQUANT 300 WKSTN, 1 EA. Category: ImageQuant CCD Imagers....
... use with T4 Polynucleotide Kinase for ... ends) of nucleic acids. In the ... the 5' phosphate group from DNA ... Gamma-phosphate of ATP to the free ...
JTV1 gene...
Biology Products: