Navigation Links
Nanoscale method for investigating living systems

By observing how tiny specks of crystal move through the layers of a biological membrane, a team of University of Wisconsin-Madison electrical and computer engineers has devised a new method for investigating living systems on the molecular level. The discovery could lead to an entirely new level of manipulation, imaging and understanding of the inner workings of cells.

The specks are known as quantum dots or inorganic semiconductor nanocrystals. Measuring in millionths of a millimeter, these dots are so small that the addition or removal of electrons changes the properties of the dot. The team, including Electrical and Computer Engineering Professors Dan van der Weide and Robert Blick with researchers Sujatha Ramachandran and George Kumar, found that by applying voltages to a solution of quantum dots and membranes similar to those of living cells, the dots would be pressed into the membranes. The dots formed rings, which in turn acted as portals in the membranes. These artificial portals or pores could enable a method of investigating living systems by means of semiconductor technology that until now could be theorized but not directly observed.

"To get a feeling of why this is important, you have to understand that each of our cell membranes has specific pores in them that regulate the flow of ions in and out," says Blick. "Through these ions, your cells will build up electric potential and communicate with other cells. This is how signal transduction is performed in your body, but it is also how chemicals react with your body. When, for example, caffeine enters a cell it stimulates the opening and closing of these ion channels. What we've found is that these quantum dots can form artificial pores that enhance the flow of ions and which we can control from the outside via voltage."

Quantum dots can be encoded with different colors making them useful as fluorescent labels for staining cells. Their resistance to photobleaching and physical siz
'"/>

Source:University of Wisconsin


Page: 1 2

Related biology news :

1. Nanoscale Diagnostic Sets Sights on Alzheimers
2. Nanoscale microscope sheds first light on gene repair
3. Color-blind method opens new doors in DNA sequencing
4. New imaging method gives early indication if brain cancer therapy is effective, U-M study shows
5. Studies reveal methods viruses use to sidestep immune system
6. An entropy-based gene selection method for cancer classification using microarray data
7. New methods of gene delivery using lasers
8. Breakthrough method in nanoparticle synthesis paves the way for new pharmaceutical and biomedical applications
9. Shift of weather patterns necessitates rethinking of reforestation methods
10. Scientists use manufacturing methods to reconstruct mastodon
11. Researchers develop promising new gene network analysis method
Post Your Comments:
*Name:
*Comment:
*Email:
TAG: Nanoscale method for investigating living systems

(Date:9/18/2014)... the fish world, are the ideal animal in which ... moved from the ocean into tens of thousands of ... changing their skeleton to adapt to the new environment. ... sticklebacks now have turned up one of the genes ... change in that gene,s regulation in a freshwater population ...
(Date:9/18/2014)... has found clownfish larvae can swim up to 400 kilometres ... to cope with environmental change. , Clownfish spend their entire ... as babies they must wander the open ocean, says study ... for Coral Reef Studies (Coral CoE) at James Cook University. ... but now we,ve been given a rare glimpse into how ...
(Date:9/17/2014)... From accessible and affordable health care to reproductive ... depend on the ability of people to identify ... openly and respectfully, and find the most defensible ... practices to support these societal conversations?, The Hastings ... of Bioethical Issues have teamed up to publish ...
Breaking Biology News(10 mins):Counting fish teeth reveals regulatory DNA changes behind rapid evolution, adaptation 2Counting fish teeth reveals regulatory DNA changes behind rapid evolution, adaptation 3Nemo's epic journey to find a new home 2Why bioethics literacy matters 2Why bioethics literacy matters 3
... change in the Southwest will likely eliminate Joshua trees from ... years, according to a new study led by U.S. Geological ... of future climate, an analysis of the climatic tolerances of ... to project the future distribution of Joshua trees. The study ...
... Washington, D.C.Recent climate modeling has shown that reducing ... would give the Earth a wetter climate in ... Ecology scientists Long Cao and Ken Caldeira offers ... when atmospheric carbon dioxide (CO2) concentrations are decreasing. ...
... European Molecular Biology Laboratory (EMBL) in Heidelberg, Germany, have ... any protein of their choice with any of a ... by introducing a single reactive artificial amino acid. Published ... to label even rare proteins very precisely for optical ...
Cached Biology News:Uncertain future for Joshua trees projected with climate change 2Cutting carbon dioxide helps prevent drying 2
(Date:9/18/2014)... (PRWEB) September 18, 2014 A novel ... an MRI scanner is currently being tested as part ... Women's Hospital in Boston with the aim of determining ... can make prostate cancer biopsies faster, more accurate, less ... system also has the potential to deliver prostate cancer ...
(Date:9/18/2014)... , September 18, 2014 /PRNewswire/ ... Markets ( http://www.researchandmarkets.com/research/czvg3s/biocompatible ) has announced ... Materials - Global Strategic Business Report" ... (Logo: http://photos.prnewswire.com/prnh/20130307/600769) ,This report analyzes the ... US$ Million by the following Product ...
(Date:9/18/2014)... (PRWEB) September 18, 2014 On Tuesday, ... and Sen. Jim Risch for National Lab Day on ... from across the national laboratory system. Durbin and Risch ... aims to increase awareness of the reach of the ... and discoveries to address some of our nation's most ...
(Date:9/18/2014)... DUBLIN , Sept. 18, 2014 ... addition of the "Global N-acetylcysteine Industry Report ... The Global N-acetylcysteine Industry Report 2014 is ... state of the global N-acetylcysteine industry. ... industry including definitions, classifications, applications and industry chain ...
Breaking Biology Technology:Worcester Polytechnic Institute Participates in Clinical Trial for MRI-Compatible Robot Designed to Improve Accuracy of Prostate Cancer Biopsies 2Worcester Polytechnic Institute Participates in Clinical Trial for MRI-Compatible Robot Designed to Improve Accuracy of Prostate Cancer Biopsies 3Worcester Polytechnic Institute Participates in Clinical Trial for MRI-Compatible Robot Designed to Improve Accuracy of Prostate Cancer Biopsies 4Worcester Polytechnic Institute Participates in Clinical Trial for MRI-Compatible Robot Designed to Improve Accuracy of Prostate Cancer Biopsies 5Worcester Polytechnic Institute Participates in Clinical Trial for MRI-Compatible Robot Designed to Improve Accuracy of Prostate Cancer Biopsies 6Biocompatible Materials - Global Strategic Business Report 2014 2Biocompatible Materials - Global Strategic Business Report 2014 3Lab Day Highlight Labs' Contribution to U.S. Competitiveness and Innovation 2Lab Day Highlight Labs' Contribution to U.S. Competitiveness and Innovation 3Global N-acetylcysteine Industry Report 2014 2
... For the second time in three years, the Best of ... Labs(R) as Utah,s top, company in the Medical ... /PRNewswire/ - American Biotech Labs, LLC (ABL), developer of a new ... today announced that the company has won the 2009 Utah Best ...
... ) today announced that management will present at the following two investor ... Global Healthcare Conference, Tuesday, June 9, 2009, ... Conference, Thursday, June 11, 2009, 11:00 ... and available for replay from Dendreon,s website, www.dendreon.com . ...
... Burbano to senior associate and project architects Tess Kavanagh and ... firm ( http://www.ratcliffarch.com ) provides a ... healthcare, academic and civic clients throughout the Western United States. ... 20 years of architectural design experience. He is currently ...
Cached Biology Technology:American Biotech Labs(R) Garners 2009 Utah Best of State Award 2American Biotech Labs(R) Garners 2009 Utah Best of State Award 3Ratcliff Promotes Jorge Burbano to Senior Associate; Tess Kavanagh and Tony Keung to Associate 2
Purified anti-mouse Tim-1...
Request Info...
Request Info...
Anti-ADP-Ribosylation Factor 1, clone 3F1 Immunogen: Synthetic peptide corresponding to the C-terminal amino acid sequence of human ARF1. Available Date: 38495...
Biology Products: