Navigation Links
NIAID DNA vaccine for H5N1 avian influenza enters human trial

The first human trial of a DNA vaccine designed to prevent H5N1 avian influenza infection began on December 21, 2006, when the vaccine was administered to the first volunteer at the National Institutes of Health (NIH) Clinical Center in Bethesda, MD. Scientists from the Vaccine Research Center (VRC) at the National Institute of Allergy and Infectious Diseases (NIAID), one of the NIH Institutes, designed the vaccine. The vaccine does not contain any infectious material from the influenza virus.

Unlike conventional flu vaccines, which are developed by growing the influenza virus in hens' eggs and then administered as a weakened or killed form of the virus, DNA-based vaccines contain only portions of the influenza virus' genetic material. Once inside the body, the DNA instructs human cells to make proteins that act as a vaccine against the virus.

VRC Director Gary Nabel, M.D., Ph.D., together with a team of scientists from the VRC recognized the potential for employing new vaccine technology against influenza, a disease for which effective vaccines have long been made, but for which the reliability of supply and manufacturing capacity has been problematic. Dr. Nabel and his colleagues previously have shown the DNA vaccine approach to be effective against influenza viruses in animal models, including highly pathogenic viruses such as the H5N1 strain and the H1N1 virus that caused the deadly 1918 pandemic. The DNA vaccine used in this study is similar to other investigational vaccines evaluated by the VRC that hold promise for controlling other viruses, such as HIV, Ebola, SARS and West Nile.

"An effective H5N1 influenza vaccine would provide a potentially life-saving advance against a global health threat," notes NIAID Director Anthony S. Fauci, M.D. "More broadly, development of this DNA vaccine technology has the potential to improve our production capacity for vaccines to prevent seasonal influenza and other diseases."

"This i
'"/>

Source:NIH/National Institute of Allergy and Infectious Diseases


Page: 1 2 3

Related biology news :

1. NIAID Initiates Trial of Experimental Avian Flu Vaccine
2. NIAID begins clinical trial of West Nile virus vaccine
3. New NIAID grants strengthen national biodefense and emerging infectious diseases research network
4. NIAID researchers show how promising TB drug works
5. NIAID expands capability for influenza research and surveillance
6. Research advances quest for HIV-1 vaccine
7. A much-needed shot in the arm for HIV vaccine development
8. Discovery of key proteins shape could lead to improved bacterial pneumonia vaccine
9. Gene vaccine for Alzheimers disease shows promising results
10. Influenza vaccine uses insect cells to speed development
11. Norovirus, AIDS vaccine and Hepatitis Virus
Post Your Comments:
*Name:
*Comment:
*Email:
TAG: NIAID DNA vaccine for avian influenza enters human trial

(Date:4/6/2015)... 6, 2015 NXT-ID, Inc. (NASDAQ: NXTD ... company focused on the growing mobile commerce market, ... 62/143028 for MINIATURE, MULTI-PURPOSE ANTENNA METHOD AND ... NXT-ID introduces a new revolutionary method and ... the use of miniature antenna modules for multiple ...
(Date:4/1/2015)... 1, 2015  NXT-ID, Inc. (NASDAQ: NXTD ) ... on the growing mobile commerce market, announces the second ... is underway to early access pre-order customers. ... at retail outlets including Walmart, Target, AT&T, Dunkin, Donuts, ... was accepted at all outlets and very easy to ...
(Date:3/26/2015)... The Granite Club, ... club, today announced it has implemented a state-of-the-art access ... for members and staff, while restricting access to authorized ... selected FST,s IMID Access system because it has the ... and staff, in addition to unparalleled security," said ...
Breaking Biology News(10 mins):NXT-ID Patents Miniature, Low Power Wireless Magnetic Stripe 2NXT-ID Patents Miniature, Low Power Wireless Magnetic Stripe 3NXT-ID Patents Miniature, Low Power Wireless Magnetic Stripe 4NXT-ID Reports Second Shipment of Wocket Smart Wallets Underway to Early Access Pre-order Customers and Provides User Feedback 2NXT-ID Reports Second Shipment of Wocket Smart Wallets Underway to Early Access Pre-order Customers and Provides User Feedback 3NXT-ID Reports Second Shipment of Wocket Smart Wallets Underway to Early Access Pre-order Customers and Provides User Feedback 4Granite Club First Private Club in North America to Implement FST Biometrics Secure Access Solution, as Part of Multi-million Dollar Expansion 2
... CAMBRIDGE, Mass. -- About one-third of the human population is ... most of them don,t know it. Though Toxoplasma ... harmful to individuals with suppressed immune systems, and to fetuses ... are found in dirt and easily infect farm animals such ...
... cancer is the sixth most common type of cancer and ... women without any known risk factors. Now, researchers at Fox ... of precancerous cells in the mouth and thus promote the ... The new results, published in the January issue of ...
... Anatomist,s (AAA) will present its 2011 Young Investigator Awards ... in their respective fields and show remarkable promise of ... lecture at the AAA Annual Meeting during Experimental Biology ... Washington Convention Center, Washington, DC, Room 102A). ...
Cached Biology News:MIT researchers study the danger of toxoplasma parasites 2Estrogen may help precancerous cells spread in oral cavity 2American Association of Anatomists announces young investigator award winners 2
(Date:4/30/2015)... Calif. , April 30, 2015  Asterias Biotherapeutics, ... the emerging field of regenerative medicine, today announced that ... on Thursday, May 7, 2015 after the close of ... conference call and webcast on Thursday, May 7, 2015 ... discuss the results and recent corporate developments. ...
(Date:4/30/2015)... Available in select spas in the ... Phytomer’s DOUCEUR INTEMPORELLE Restorative Shield Cream provides immediate ... the weakening threat of inflammaging, aging directly caused ... star ingredient GLYCOSEA, a complex of restructuring plankton ... soothing minerals and trace elements. GLYCOSEA works to ...
(Date:4/29/2015)... According to a new market research report “Vibration ... Component (Accelerometer, Proximity Probe, & Others), Application (Aerospace ... Others), & Geography - Global Forecast to 2020", ... Million by 2020, at a CAGR of 6.6%. ... figures spread through 205 pages and in-depth TOC ...
(Date:4/29/2015)... 29, 2015 Cambrex Corporation (NYSE: CBM ) ... on Friday, May 1, 2015 before the market opens. ... will host a conference call to discuss the financial results. ... , Friday, May 1, 2015 at 8:30 a.m. ... for U.S.1-719-325-2454 for International  Passcode:  7993632 Dial-in Replay: ...
Breaking Biology Technology:Asterias Biotherapeutics to Report First Quarter Results on May 7, 2015 2Asterias Biotherapeutics to Report First Quarter Results on May 7, 2015 3Phytomer introduces DOUCEUR INTEMPORELLE Restorative Shield Cream 2Phytomer introduces DOUCEUR INTEMPORELLE Restorative Shield Cream 3Vibration Monitoring Equipment (Portable & Non-Portable) Market worth $1,453.76 Million by 2020 - New Report by MarketsandMarkets 2Vibration Monitoring Equipment (Portable & Non-Portable) Market worth $1,453.76 Million by 2020 - New Report by MarketsandMarkets 3Vibration Monitoring Equipment (Portable & Non-Portable) Market worth $1,453.76 Million by 2020 - New Report by MarketsandMarkets 4
... life,sDHA™ and the National Center for ... year for Beautiful Minds: Finding Your Lifelong Potential ... Americans to develop and maintain healthy, beautiful minds by incorporating ... health – diet and nutrition, physical health, mental health and ...
... ,   - CNIT Paris La ... of services offered by the ALTEN Group to the Telecom industry ... in April 2011. The integration is a success, and the telecom ... "Broadband World Forum 2011" exhibition at CNIT Paris La Defense. ...
... This release is available in German . ... plastic foils, have excellent potential to lower the manufacturing ... cost, thus enabling affordable solar electricity in the near ... films have been lacking behind in performance compared to ...
Cached Biology Technology:Proactive Brain Health Critical as Americans' Life Expectancy Reaches All Time High 2Proactive Brain Health Critical as Americans' Life Expectancy Reaches All Time High 3Proactive Brain Health Critical as Americans' Life Expectancy Reaches All Time High 4ALTEN and Calsoft Labs at the BWF 2011 Exhibition 2How to produce flexible CIGS solar cells with record efficiency 2
A compact, high-speed single tube reader unit designed for benchtop 2D barcode reading. The unit can be used with all of ABgene's 2D barcoded tubes, including the 2ml CryoCode tube....
PTFE/red rubber septum silver aluminum seal ,11 mm seal diam. ...
... stops PCR carry-over contamination, which prevents ... PCR products from previous PCR amplifications ... which improves amplification ,Optimized for use ... GeneAmp instrument systems , The GeneAmp ...
... hydrolytic enzyme that catalyzes the conversion,of ... maltose, maltotriose and,dextrins. The level of ... human,body are of clinical importance,1-3 while ... for industry.4, The EnzChek Amylase Assay ...
Biology Products: