Navigation Links
NHGRI expands effort to revolutionize sequencing technologies

"Modulating Nucleotide Size in DNA for Detection by Nanopore"

This group will design and synthesize modified nucleotides of different sizes, which can be incorporated into DNA. When passed through nanopores, the differences between these modified nucleotides will be easier to detect, producing clean sequencing data.

Bhubaneswar (Bud) Mishra, Ph.D., New York University, New York.
$585,000 (2 years)
"Haplotype Sequencing Via Single Molecule Hybridization"

Investigators from this group will hybridize short DNA probes to genomic DNA fragments to determine sequence information. In addition, they will use optical mapping to create restriction maps to help assemble the genome once it is sequenced. The group will then demonstrate how to combine the sequence and maps into distinct haplotype sequences.

Gregory L. Timp, Ph.D., University of Illinois at Urbana-Champaign.
$2.1 million (3 years)
"Sequencing a DNA Molecule Using a Synthetic Nanopore"

This group will explore the feasibility of sequencing a DNA molecule using a type of silicon integrated circuit. The circuit incorporates a nanopore mechanism with a molecular trap that forces the DNA molecule to oscillate back and forth between electrodes, measuring the electrical signal associated with each specific base.

Stephen W. Turner, Ph.D., Nanofluidics, Menlo Park, Calif.
$6.6 million (3 years)
"Real-Time Multiplex Single-Molecule DNA Sequencing"

This group will leverage their "zero-mode waveguide" technology to detect single nucleotides in real-time, as they are incorporated by a DNA polymerase into a growing DNA molecule. The ultimate goal is to create a real-time, multiplex single-molecule DNA sequencing system that produces sequence reads containing hundreds of thousands of nucleotides.

"$100,000 Genome" Grants

NHGRI's "Near-Term Development for Genome Sequencing" grants will support research aimed at sequencing a
'"/>

Source:NIH


Page: 1 2 3 4 5

Related biology news :

1. NHGRI targets 12 more organisms for genome sequencing
2. NHGRI Selects 13 More Organisms for Genome Sequencing
3. NHGRI announces new sequencing targets
4. NHGRI announces latest sequencing targets
5. NHGRI aims to make DNA sequencing faster, more cost effective
6. International HapMap consortium expands mapping effort
7. Gene expands malarias invasion options
8. MWG Biotech expands siMAX?siRNA portfolio with new scales, lengths and design tools
9. New book expands biological classifications to account for alien life
10. New study expands understanding of the role of RNA editing in gene control
11. NIAID expands capability for influenza research and surveillance
Post Your Comments:
(Date:12/11/2014)... N.C. , Dec. 10, 2014  That blood pressure ... quite a while. Hypertension – the medical term for high ... the early 1800s, and the inflatable cuff that,s used in ... doesn,t, however, mean there,s nothing new about hypertension, its triggers ... long-held beliefs about the condition and the best ways to ...
(Date:12/10/2014)... 2014  Wake Forest Baptist Medical Center today announced plans ... of Medicine. Funding for this $50 million capital project ... be publicly launched next summer. The ... 60 series R.J. Reynolds Tobacco Company complex, adjacent to ... immediately with plans to be ready to welcome medical ...
(Date:12/5/2014)... , Dec. 4, 2014 Increased ... boosted investments in new testing and inspection technologies. ... given rise to a range of innovative test ... requirements of Generation Y, which is generally more ... a result, product development strategies of test equipment ...
Breaking Biology News(10 mins):Research points to need for new approaches to treatment of high blood pressure 2Research points to need for new approaches to treatment of high blood pressure 3Research points to need for new approaches to treatment of high blood pressure 4Wake Forest Baptist to Build New Medical Education Facility In Wake Forest Innovation Quarter 2Wake Forest Baptist to Build New Medical Education Facility In Wake Forest Innovation Quarter 3Wake Forest Baptist to Build New Medical Education Facility In Wake Forest Innovation Quarter 4Emerging Technologies Enable Smarter Monitoring of Assets, Push Industrial Testing, Inspection and Monitoring Market 2Emerging Technologies Enable Smarter Monitoring of Assets, Push Industrial Testing, Inspection and Monitoring Market 3Emerging Technologies Enable Smarter Monitoring of Assets, Push Industrial Testing, Inspection and Monitoring Market 4
... 8, 2013 How many breakthrough new drugs never ... high risk of liver damage when the drug actually ... international research efforts to modernize tests for drug-induced liver ... & Exposition of the American Chemical Society (ACS), the ...
... , Sept. 6, 2013  Daniel P. Linskey, superintendent-in-chief of the ... Learned from Boston Marathon Bombings" at the 2013 IEEE International ... Linskey,s talk will focus on the aftermath ... response of his department and federal enforcement agencies that ultimately ...
... researchers has discovered the cranium of a fossil ape from ... cranium of the fossil ape Lufengpithecus is significant, ... at Penn State. Jablonski noted that juvenile crania of ... especially those of infants and young juveniles. This cranium is ...
Cached Biology News:Better tests for liver toxicity would mean more medicines -- and safer medicines -- for patients 2Better tests for liver toxicity would mean more medicines -- and safer medicines -- for patients 3Boston Police Chief to Address Boston Marathon Bombings at IEEE Homeland Security Conference in Waltham, Mass., on 12 November 2Researchers discover rare fossil ape cranium in China 2
(Date:12/17/2014)... (PRWEB) December 17, 2014 Gene ... that it has entered into a technology access ... (ADM) to apply DNA2.0’s proprietary protein engineering technology, ... process. , “We are extremely excited that the ... platform. This proprietary bioengineering technology has now ...
(Date:12/17/2014)... SOUTH SAN FRANCISCO, Calif. , Dec. 17, ... positive results of a Phase 2 study evaluating ... for the treatment of patients with severe, chronic ... the current standard of care, including topical steroids ... endpoint was percent change in Visual Analog Scale ...
(Date:12/15/2014)...  GlassesOff Inc. (OTCBB: GLSO) announced today the appointment ... director of the Company,s Board of Directors. ... its CEO until its acquisition by Stanley Black ... Recognized as the inventor of the first Wi-Fi-based Active ... -based RFID solutions focused on improving operational efficiency, safety ...
(Date:12/13/2014)... (PRWEB) December 12, 2014 Clarassance, a ... announced its new name: Therabron Therapeutics , Inc. ... and bronchioles (a type of structure in the lungs ... company’s mission to develop novel protein therapeutics for the ... directors decided to change the name to mark the ...
Breaking Biology Technology:ADM and DNA2.0 Enter Into Protein Engineering Technology Access and Service Agreement 2Velocity Pharmaceutical Development, LLC and Tigercat Pharma, Inc. Announce Phase 2 Results for VPD-737 in Patients With Chronic Pruritus 2Velocity Pharmaceutical Development, LLC and Tigercat Pharma, Inc. Announce Phase 2 Results for VPD-737 in Patients With Chronic Pruritus 3Velocity Pharmaceutical Development, LLC and Tigercat Pharma, Inc. Announce Phase 2 Results for VPD-737 in Patients With Chronic Pruritus 4AeroScout Founder Joins GlassesOff's Board of Directors 2AeroScout Founder Joins GlassesOff's Board of Directors 3Maryland-based Biotech Company's Path Forward in Treating Respiratory Diseases Sparks Name Change 2
... Cingular merger with AT&T? , ,I've read the business stories ... the assets and customers of AT&T Wireless for $41 billion. ... 2 carrier Verizon by 9 million subscribers. The one hitch ... brand and plans to launch a new wireless service under ...
... Many organizations talk a good game about interpersonal skills, influence ... there's a pretty clear chain of command that runs right ... Technology (DoIT) at the University of Wisconsin-Madison, Annie Stunden ... that many more staff with IT responsibilities in other departments ...
... in Carlsbad, California. , Dynal : 400+ employees worldwide, ... in Oslo, Norway. Brown Deer, Wis. ... Dynal Biotech ASA , whose U.S. operations are based ... for $380.4 million. , ,Invitrogen has considered the ...
Cached Biology Technology:Cingular confusion 2Cingular confusion 3Annie Stunden, CIO at the University of Wisconsin-Madison 2Annie Stunden, CIO at the University of Wisconsin-Madison 3Annie Stunden, CIO at the University of Wisconsin-Madison 4Invitrogen to buy Norwegian biotech with operations in Brown Deer 2
...
Whole blood is collected from healthy guinea pigs of either sex from US source which are free of visible diseases at time of blood collection. Hemolytic titer: CH50 = 435 units...
... l-[35S]in vitro cell labeling mix, ... *Aqueous solution stabilized with 0.1% ... pyridine 3,4-dicarboxylic acid. *Amino acid ... labeling containing l-[35S]Methionine and l-[35S]Cysteine. ...
...
Biology Products: