Navigation Links
Muscle and bone from an ink-jet printer

A Pittsburgh-based research team has used an innovative inkjet system to print unique "bio-ink" patterns that directed adult muscle-derived stem cells from mice to differentiate into both muscle cells and bone cells.

This is the first report of a system that can pattern the formation of multiple tissues from a single population of adult stem cells.

Bioengineers from Carnegie Mellon University’s Robotics Institute and the Institute for Complex Engineered Systems teamed with stem cell biologists from the University of Pittsburgh School of Medicine and Children’s Hospital of Pittsburgh to demonstrate the use of ink-jet printing to pattern “bio-inks?combinations of growth factors to control the fate of stem cells. Working with mice, the Pittsburgh biologists have gained considerable experience in using growth factors to control proliferation and differentiation in populations of “muscle-derived stem cells,?or MDSCs. Previous work by University of Pittsburgh researchers has demonstrated the ability of MDSCs to repair muscle in a model for Duchenne Muscular Dystrophy, improve cardiac function following heart failure, and heal large bone defects in the skull. Controlling not only what types of cells differentiate from stem cells, but also gaining spatial control of stem cell differentiation, are important capabilities if researchers are to engineer replacement tissues that might be used in treating disease, trauma, or genetic abnormalities. Spatial patterning of stem cell differentiation through delivery of bio-inks with an ink-jet printer will offer the Pittsburgh researchers a whole new level of complexity and control.

The custom built ink-jet printer, which was developed at Carnegie Mellon, can deposit bio-inks in virtually any design, pattern, or concentration, laying down patterns on fibrin-coated slides placed in culture dishes containing MDSCs. Based on pattern, dose, or factor printed by the ink-jet, the MDSCs could be directed when to
'"/>

Source:American Society for Cell Biology


Page: 1 2

Related biology news :

1. Muscle-targeted gene therapy reverses rare muscular dystrophy in mice
2. X-Ray Beams And Fruit Fly Flight Simulator Aid Scientists View Of Muscle Power
3. Young Blood Revives Aging Muscles, Stanford Researchers Find
4. Muscle repair: Making a good system better, faster; implications for aging, disease
Post Your Comments:
*Name:
*Comment:
*Email:
TAG: Muscle and bone from ink jet printer

(Date:8/10/2015)... and TELTOW, Germany , August ... (SMI), a world leader in Eye Tracking Technology ... of its OEM Eye Tracking Platform for integration into ... Platform contains reference designs for seamless integration of eye ... virtual reality HMDs and augmented reality smart glasses. Omnivision,s ...
(Date:8/6/2015)... CITY, Calif. , Aug. 6, 2015 /PRNewswire/ ... Valley) will visit Crossmatch ™ to learn ... networks and protect data. Crossmatch is a world ... whose technologies and expertise are helping federal agencies ... efficiency and security.   "The vast ...
(Date:8/6/2015)... , Aug. 6, 2015 Synaptics Inc. ... human interface solutions, today announced collaboration with Microsoft ... Windows 10. Microsoft leveraged Synaptics, deep expertise in ... system. Through stringent testing, Synaptics, ... certified with Microsoft,s Precision TouchPad (PTP) specification empowering ...
Breaking Biology News(10 mins):SMI Completes OEM Eye Tracking Platform to Cover All Consumer Displays 2SMI Completes OEM Eye Tracking Platform to Cover All Consumer Displays 3Rep. Honda to Visit Crossmatch in Redwood City 2Synaptics Chosen for Human Interface Co-Development on Windows 10 2
... Vitamin and mineral supplements can enhance mental energy and ... prone to anxiety and depression, according to a July ... Technologists (IFT) Annual Meeting & Food Expo held at ... faculty of medicine at the University of Calgary, Alberta, ...
... size and parental behavior are the key drivers in children,s ... the 2013 Institute of Food Technologists (IFT) Annual Meeting & ... crowd of more than 200 conference attendees heard new insights ... eating behaviors are and how the industry and parents can ...
... (OGL), New England Biolabs, Inc., and Northeastern University have reached ... tissue from the world,s most rare, strange, and remarkable ocean ... Ocean Genome Legacy , Founded in 2001 ... New England Biolabs, OGL is a non-profit environmental research organization ...
Cached Biology News:Taste rules for kids and healthy food choices 2Collection that may hold key to ocean's mysteries looks to expand in new waterfront home 2
(Date:9/1/2015)... ... September 01, 2015 , ... Leading ... neuro and pain management space join prominent academics and key investors for Neuro ... Harvard Medical School in Boston. , Neuro Advance Boston focuses on the ...
(Date:9/1/2015)... ... September 01, 2015 , ... A new host-based ... researchers at the Keck Graduate Institute and its collaborators. The discovery has the ... were published online on August 27 by Scientific Reports, an open access research ...
(Date:8/31/2015)... ... 2015 , ... The Global Supply Chain Resiliency Council was ... practitioners with luminaries and thought leaders to advance the professional discipline through opportunities ... and performance excellence. At that time its principle sponsor, Resilinc , stated ...
(Date:8/31/2015)... , Aug. 31, 2015 Research and ... the "Argentina Biomedical Sensors Market - Growth, Trends ... The Argentina Biomedical Sensors market is estimated ... 1.17% over the period 2014-2020 The near ... the genetic formulation of each individual. These sensors can ...
Breaking Biology Technology:Neuro Advance Boston Brings Together Leading Neuroscience Experts on October 14 at Harvard Medical School 2Scientists Discover New Use for an Old Therapy Inhibiting Deadly Pathogens Including Ebola and Anthrax 2Scientists Discover New Use for an Old Therapy Inhibiting Deadly Pathogens Including Ebola and Anthrax 3Scientists Discover New Use for an Old Therapy Inhibiting Deadly Pathogens Including Ebola and Anthrax 4Global Supply Chain Resiliency Council Announces Incorporation and Web Site Launch 2Global Supply Chain Resiliency Council Announces Incorporation and Web Site Launch 3Argentina Biomedical Sensors Market Report 2015 - Growth, Trends & Forecasts 2014-2020 2
... , - German Chemical Parks ... The number of employees in German chemical parks ... In this same period, the number of,companies doing business at ... today by Dr. Klaus-Dieter Juszak, Chairman of the,German Sector Group ...
... EXPANSION INTO EUROPE AND STRENGTHENS ITS SENIOR MANAGEMENT ... 12 OmniComm Systems, Inc. (OTC Bulletin Board: OMCM.OB), ... for clinical trials, today announced that it has strengthened ... of Dr. Wolfgang Summa. As Executive Vice President, Europe ...
... today that it has acquired from biotechnology company Antisoma ... film-coated tablets), an oral B-cell chronic lymphocytic leukemia (CLL) ... United States for use as a second-line therapy to ... pleased to add Oforta to our existing oncology portfolio, ...
Cached Biology Technology:10,000 New Jobs, Investments Increased 210,000 New Jobs, Investments Increased 3OmniComm Systems Appoints EDC Veteran Dr. Wolfgang Summa to Executive Vice President, Europe & Asia/Pacific 2OmniComm Systems Appoints EDC Veteran Dr. Wolfgang Summa to Executive Vice President, Europe & Asia/Pacific 3Sanofi-aventis U.S. to Acquire Oral Chronic Lymphocytic Leukemia Treatment 2Sanofi-aventis U.S. to Acquire Oral Chronic Lymphocytic Leukemia Treatment 3
... , CapSure HS and CapSure Macro LCM ... of populations of pure cells from tissue ... Microdissection., Ensure the Integrity of Microdissected ... CapSure LCM Caps have a patented transfer ...
Opticon continuous fluorescence detector; includes optical base, analysis software, computer and monitor (this is an accessory for the DNA Engine thermal cyclers which must be ordered seperately)...
... on one plate. The new ArraySlide 96 ... (7mm x 7mm) individual printing surfaces for ... analysis studies. Unlike other systems, this device ... presence of contaminating adhesives. The chamber itself ...
... chambers for sealing hybridization reactions on slides. The ... on a glass slide. Reaction solution is added ... are then sealed with plastic sealing dots. Dots ... of reaction fluid. These chambers enclose a 20 ...
Biology Products: