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Multiple malaria infection inhibits spread of parasite

r were found to occur. The number of gametocytes per person was season and age dependent. Children were found to be by far the most important source of malaria transmission in the area. In the village Koundou, the number of infectious bites was about five times as high as in the capital. There previous research had revealed 177 infectious bites.

Test

The existing laboratory test for malaria immunity did not yet work optimally. Therefore the researchers first modified this method before starting the research on immunity. With the improved test, the researchers studied how people not previously exposed to malaria become infected or immune. Migrants in the province of Papua in Indonesia, who had not previously been exposed to malaria were investigated for this purpose. Malaria is highly prevalent in Papua. After just one to four malaria infections the immunity against the infectious gametocytes increased. Immunity therefore develops quickly after exposure to an infection. The researchers expect that the modified methods will make it possible to carry out more detailed studies into the development and maintenance of immunity within the population.


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Source:Netherlands Organization for Scientific Research


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