Navigation Links
Mouse genome much more complex than expected

Over 100 scientists worldwide publish joint study in Science

More than 100 scientists from Australia, Asia, Europe and the US have been probing the genome of the mouse in a joint study lasting several years. Their results in some aspects have completely overturned geneticists' traditional assumptions. The findings are available in the prestigious journal Science on 2nd September. The general conclusion of the study is that the genome of mammals is much more complex than was hitherto supposed.

The genetic material of mammals, the DNA, can be compared to an enormous encyclopedia containing the complete blueprint of the animal in question. Yet this comparison is misleading: over the past few years it has been realised that on most pages of the encyclopedia there is no information at all: they contain a chaotic sequence of letters. Mixed in among these pages there are intelligible pages from time to time, the genes.

The DNA encyclopedia is stored in the nuclei of the cells. If the body is to produce a specific protein, the appropriate page of the encyclopedia is copied (rewritten or 'transcribed'). Only the copies can leave the cell nucleus. They consist of a DNA-like material known as mRNA. Each mRNA contains the blueprint for precisely one specific protein ?this at least has been the traditional doctrine.

Three years ago the DNA of the mouse was completely sequenced. An international research team consisting of more than 100 scientists has been attempting since then to isolate and analyse the entire mRNA transcripts in the mouse. Their most astonishing finding is that more than 60 per cent of all mRNAs are not protein blueprints at all. 'We don't know what the function of these RNAs is,' the Bonn neurobiologist Professor Andreas Zimmer admits. However, they seem to be extremely important: even in such different organisms as hens and mice these ostensibly so unimportant RNAs are very similar. If they really had no function they would hav
'"/>

Source:University of Bonn


Page: 1 2

Related biology news :

1. Mouse brain cells rapidly recover after Alzheimers plaques are cleared
2. Mouse brain tumors mimic those in human genetic disorder
3. Research Using Mouse Models Reveals A Novel Key Player In The Initiation Of Colon Cancer
4. Mouse gene shows new mechanism behind cardiac infarction in man
5. Mouse with designer liver has enhanced glucose tolerance, insulin response
6. Agilent Technologies Introduces First Commercial Mouse Microarray for Comparative Genomic Hybridization Research
7. Mouse study: New muscle-building agent beats all previous ones
8. Mouse study reveals human X-SCID gene therapy poses substantial cancer risk
9. Mouse to man: The story of chromosomes
10. Mouse mimics chronic leukemia, will aid drug development
11. Mouse study reveals new clues about virulence of 1918 influenza virus
Post Your Comments:
*Name:
*Comment:
*Email:
TAG: Mouse genome much more complex than expected

(Date:12/19/2014)... Dec. 18, 2014 Research and Markets ... "Micro Market Monitor: North America Perimeter Security Systems ... http://photos.prnewswire.com/prnh/20130307/600769 The North American ... CAGR of 3.6% from 2014 to 2019. Although the ... Canada is expected to grow ...
(Date:12/17/2014)... , Dec. 15, 2014  HITLAB SM ... Practices (GCP) audit to confirm its adherence to ... This accomplishment enables HITLAB to conduct regulated smart ... highest principles for patient safety and research quality. ... healthcare access, quality, and delivery with innovative technology," ...
(Date:12/11/2014)... DUBLIN , Dec. 09, 2014 Research ... http://photos.prnewswire.com/prnh/20130307/600769 ( http://www.researchandmarkets.com/research/twhjll/biometrics_market ) ... Market in the APAC Region 2015-2019"  report to ... emerging in this market is advances in technology. ... to upgrade biometric solutions to the latest standard ...
Breaking Biology News(10 mins):Micro Market Monitor: North America Perimeter Security Systems Market (Intrusion Detection Sensor, Video Surveillance, Communication/Alarm and Notification, Access Control System) 2Micro Market Monitor: North America Perimeter Security Systems Market (Intrusion Detection Sensor, Video Surveillance, Communication/Alarm and Notification, Access Control System) 3HITLAB Completes GCP Audit for FDA Smart Device & App Compliance 2Biometrics Market in the APAC Region 2015-2019: Key Vendors are 3M Cogent, NEC, Safran and Suprema 2
... could be used as an early warning system to ... British Ecological Society's Journal of Applied Ecology has found. ... and vocal mimicry, this is the first study to ... on song-matching. , Ecologists recorded and analysed the songs ...
... Sea Grant researchers have isolated a new peptide ... implications for managing many diseases in oysters. , ... may protect against bacteria in Crassostrea virginica, a ... important economically to Atlantic and Gulf Coast fisheries. ...
... Computer scientists and biologists at the Department of ... that can select tens of thousands of high-quality ... and automatically, with accuracy approaching that of experienced ... as "particle picking by segmentation," promises to greatly ...
Cached Biology News:Bird song changes sound alarm over habitat fragmentation 2Picking particles faster than one at a time 2Picking particles faster than one at a time 3Picking particles faster than one at a time 4Picking particles faster than one at a time 5
(Date:12/19/2014)... Lawrence, MA (PRWEB) December 19, 2014 ... flow MRLAFMQ test for the Detection of Aflatoxin M1 ... test to receive independent third party validation. The peer ... Science Unit of the Institute for Agricultural and Fisheries ... Francis Group. , Aflatoxin B1, the most toxic ...
(Date:12/19/2014)... Naurex Inc., a biopharmaceutical company leveraging its ... the central nervous system, today announced that Norbert ... present at the 33 rd annual J.P. Morgan ... 3:00 p.m. PST on Tuesday, January 13, 2015, at ... Calif. About Naurex Inc. ...
(Date:12/19/2014)... -- Bina Technologies, Inc. (Bina, Redwood City, ... been acquired by Roche (SIX: RO, ROG; OTCQX: RHHBY).  ... that provides a big data platform for centralized management ... the academic and translational research markets.  Bina will be ... to focus on development of their innovative genomic analysis ...
(Date:12/19/2014)... , Dec. 19, 2014 Research and Markets ... addition of the "Technology Innovations in Smart ... http://photos.prnewswire.com/prnh/20130307/600769 ... Smart Fabrics" offers a detailed assessment on technological ... Key Findings: 1. The Smart ...
Breaking Biology Technology:Charm Sciences Achieves Independent Validation of First 15 Minute Quantitative Screening Method for Aflatoxin M1 2Naurex to Present at 33rd Annual J.P. Morgan Healthcare Conference 2Bina Technologies is acquired by Roche. 2Bina Technologies is acquired by Roche. 3Technology Innovations in Smart Fabrics (Technical Insights) 2
... Hartford, Wis. -- API Software, Inc. ... Mass. plans to implement the majority of APIs ... entire community hospital. The solution will include Payrollmation ... management and Navigator human resources software. , ,The ...
... whether the Earth's ice ages occurred simultaneously in both the ... found in the high desert east of the Andes. , ... rays on minerals found in boulders carried by South American ... the University of Wisconsin-Madison has demonstrated that the Earth's most ...
... one of the greatest surnames of our period. Trump, a superb ... business empire, is also my hero. Don is a savvy global ... of "The Apprentice", a reality TV shows series, wants to own ... of the last pillars of civility of our business protocols is ...
Cached Biology Technology:Glacial records depict ice age climate in synch worldwide 2Glacial records depict ice age climate in synch worldwide 3"You're fired!" Trump wants trademark rights 2
DEAD (Asp-Glu-Ala-Asp) box polypeptide 5...
...
RayBio L Series 507: RayBio Label-based Antibody Array I (1 glass slide with 2 subarrays) Class: Antibody Array Products Product Group: Antibody Array...
Rat CXCL7/Thymus Chemokine-1 DuoSet Economy Pack, 45 Plate...
Biology Products: