Navigation Links
Molecular 'signature' protects cells from viruses

Every cell constantly produces a whole arsenal of proteins. The instruction what is to be built comes from the cell nucleus: this is where the DNA is stored, the heredity molecule in which, so to speak, the construction blueprints for all cellular proteins are stored. If a particular protein is to be produced, the appropriate command is 'copied' in the cell nucleus. The copy consists of a DNA-like substance, the RNA. Via pores in the cell nucleus it reaches the cell plasma. The individual parts of the desired protein are put together there on a kind of assembly line. In this process the assembly line follows exactly the blueprint which is stored in the relevant RNA.

This method has an Achilles heel: 'enemies' can misuse the assembly line to produce their own proteins by faking the commands. Viruses, for example, basically consist of a small protein capsule which surrounds its genetic make-up ?usually an RNA molecule. This RNA mainly contains the blueprint for new capsule proteins. By injecting its RNA into the cell, the virus re-programmes it: the cell production line then produces large numbers of new virus capsules. These are filled with virus RNA and attack more cells.

'However, the cells are not completely at the mercy of a virus attack,' Professor Gunther Hartmann, head of the Bonn University Clinic's Department of Clinical Pharmacology. 'They often recognise the alien RNA and set off the alarm: for example, they then produce what is known as the beta interferon, thereby activating specific killer cells. They also initiate the cell's suicide programme ?apoptosis. The viruses cannot then continue to breed.'

Up to now it was not known how cells distinguish their own RNA from that of the 'enemy'. The latest findings, which a Japanese research team was also involved in, now shed light on the matter: they show that the instructions from the cell's nucleus carry a kind of 'signature', which is missing in the virus commands. RNA is like a l
'"/>

Source:University of Bonn


Page: 1 2

Related biology news :

1. Molecular biology fills gaps in knowledge of bat evolution
2. Molecular machine may lead to new drugs to combat human diseases
3. Molecular Motors Cooperate In Moving Cellular Cargo, Study Shows
4. Molecular models advance the fight against malaria
5. Molecular fossils uncover link between viruses and the immune system
6. Molecular thermometers on skin cells detect heat and camphor
7. Molecular messengers perform a crucial role in the ability of injured nerve cells to heal themselves
8. Molecular steps involved in the creation of gene-silencing microRNAs identified
9. Molecular miners find pain relief drugs from the sea
10. Molecular mechanism of feather formation found
11. Molecular trigger for Huntingtons disease found
Post Your Comments:
*Name:
*Comment:
*Email:
TAG: Molecular signature protects cells from viruses

(Date:10/18/2014)... October 2014 Psychological stress and stress-related psychiatric disorders ... diseases, but the molecular mechanisms underlying this ... contribute to the development of targeted preventive ... these devastating diseases. This work is presented ... in Berlin., Now an international group of ...
(Date:10/17/2014)... Researchers from the University of Copenhagen have shown for ... the lungs of Cystic fibrosis patients, giving them the ... growth in chronic infections. , The study also discovered ... fibrosis (CF) patients was halted or slowed down by ... consumed all the oxygen and helped "suffocate" the bacteria, ...
(Date:10/16/2014)... how the bowel lining develops and, in the process, ... , The researchers produced evidence that stem cells are ... a feature of the bowel lining, and believe these ... controversial finding as scientists are still divided on the ... Chin Wee Tan and Professor Tony Burgess from the ...
Breaking Biology News(10 mins):Researchers find why depression and aging linked to increased disease risk 2Scientists opens black box on bacterial growth in cystic fibrosis lung infection 2Cryptic clues drive new theory of bowel cancer development 2
... found a smoking gun proving that increased fertilizer use over ... in atmospheric nitrous oxide, which is a major greenhouse gas ... that the cause of the increased nitrous oxide was nitrogen-based ... to nitrous oxide at a faster rate than normal. ...
... for fish with the fishing industry. The seals locally eat about ... eel as those taken by fishermen. This is the conclusion from ... Competing with the fishing industry , The grey seals in ... sizes of fish as those taken by the fishing industry. So ...
... cotton from the banks of the Nile have found what ... occurred in a major crop group within the relatively short ... into the dynamics of agriculture in the ancient world and ... climate change and water scarcity. The researchers, led by ...
Cached Biology News:Fertilizer use responsible for increase in nitrous oxide in atmosphere 2Fertilizer use responsible for increase in nitrous oxide in atmosphere 3Fertilizer use responsible for increase in nitrous oxide in atmosphere 4Gray seals consume as much fish as the fishing industry catches 2Ancient Egyptian cotton unveils secrets of domesticated crop evolution 2Ancient Egyptian cotton unveils secrets of domesticated crop evolution 3
(Date:10/18/2014)... The Asian arthroscopic devices report defines ... and forecast of revenue. The arthroscopic devices market in ... 2018, at a CAGR of 6.5% from 2013 to ... arthroscopic devices market, to get an idea of the ... the segmentation of arthroscopic devices market in the same ...
(Date:10/18/2014)... The Asia-Pacific Liquid Crystal on Silicon (LCoS) ... in Asia-Pacific with analysis and forecast of revenue. This ... is expected to reach $380.0 million by 2018, at ... Browse through the TOC of the Asia-Pacific LCoS display ... analysis provided. This also provides a glimpse of the ...
(Date:10/18/2014)... The Biomass Power industry ... years to 2014. The industry's expansion has been propelled ... that encouraged the use of biomass power. Furthermore, the ... which require local utilities to generate electricity from renewable ... Increased campaigning for green technology also influenced industry performance ...
(Date:10/18/2014)... 2014 The report " Cloud ... Text; Web; Speech; Machine; Video; Predictive Analytics: Global ... Forecasts & Analysis (2013 - 2018) ", defines ... various sub segments with an in-depth analysis and ... the factors driving this market, various restraints, and ...
Breaking Biology Technology:The Asian arthroscopic devices market is estimated to grow to $712.3 million by 2018 - New Report by MicroMarket Monitor 2The Asian arthroscopic devices market is estimated to grow to $712.3 million by 2018 - New Report by MicroMarket Monitor 3The Asian arthroscopic devices market is estimated to grow to $712.3 million by 2018 - New Report by MicroMarket Monitor 4The Asia-Pacific Liquid Crystal on Silicon (LCoS) display market is expected to reach $380.0 million by 2018 - New Report by MicroMarket Monitor 2The Asia-Pacific Liquid Crystal on Silicon (LCoS) display market is expected to reach $380.0 million by 2018 - New Report by MicroMarket Monitor 3Biomass Power in the US Industry Market Research Report from IBISWorld Has Been Updated 2Biomass Power in the US Industry Market Research Report from IBISWorld Has Been Updated 3Cloud Analytics Market (by Cloud Business Intelligence & Predictive Analytics) Expected to Cross $16.52 Billion by 2018 - New Report by MarketsandMarkets 2Cloud Analytics Market (by Cloud Business Intelligence & Predictive Analytics) Expected to Cross $16.52 Billion by 2018 - New Report by MarketsandMarkets 3Cloud Analytics Market (by Cloud Business Intelligence & Predictive Analytics) Expected to Cross $16.52 Billion by 2018 - New Report by MarketsandMarkets 4Cloud Analytics Market (by Cloud Business Intelligence & Predictive Analytics) Expected to Cross $16.52 Billion by 2018 - New Report by MarketsandMarkets 5
... 13 Savient,Pharmaceuticals, Inc. (Nasdaq: SVNT ) today ... Savient Pharmaceuticals,will present a corporate update at the upcoming ... is scheduled to begin on Tuesday, November 18, 2008 ... the St. Regis Hotel in New,York City November 18-19, ...
... Held Friday, November 14, 2008 at 9:00 a.m. Eastern ... ... Alseres,Pharmaceuticals, Inc. (Nasdaq: ALSE ) today reports operational and,financial results ... year 2008., (Logo: http://www.newscom.com/cgi-bin/prnh/20080813/NEW056LOGO ), "We are encouraged ...
... ILI ) today announced financial and business results ... Company reported a net loss of $1.6 million, or ... quarter of 2008 compared to a net,loss of $1.1 ... for the,same period last year., "Collaborations are an ...
Cached Biology Technology:Savient Pharmaceuticals to Present at the Lazard Capital Markets 5th Annual Healthcare Conference on November 18th 2Alseres Pharmaceuticals, Inc. Reports Third Quarter 2008 Operational and Financial Results 2Alseres Pharmaceuticals, Inc. Reports Third Quarter 2008 Operational and Financial Results 3Alseres Pharmaceuticals, Inc. Reports Third Quarter 2008 Operational and Financial Results 4Alseres Pharmaceuticals, Inc. Reports Third Quarter 2008 Operational and Financial Results 5Interleukin Genetics Reports Third Quarter 2008 Financial Results 2Interleukin Genetics Reports Third Quarter 2008 Financial Results 3Interleukin Genetics Reports Third Quarter 2008 Financial Results 4Interleukin Genetics Reports Third Quarter 2008 Financial Results 5Interleukin Genetics Reports Third Quarter 2008 Financial Results 6Interleukin Genetics Reports Third Quarter 2008 Financial Results 7
... Biotin Streptavidin-HRP Systems provide rapid, precise ... antigens in frozen or paraffin-embedded tissue, ... systems also facilitate double or triple ... performed simultaneously with primary antibodies of ...
... be used with all 96-well ... stacking of covered plates ... with automated systems ... are available for use with ...
SYBR Green Nucleic Acid Dye...
... is a new product number, ... product number. If showing no ... the old Sigma-Aldrich number (Z71,670-7) ... assistance. ID clarifier: non-barcoded Mfr ...
Biology Products: