Navigation Links
Molecular cabal contributes to stroke damage

n NMDAR-mediated exitotoxicity and ASIC-mediated acidotoxicity induced by ischemia, which is known to cause excessive glutamate release and acidosis. Both NMDARs and [calcium permeable] ASICs have now been implicated in ischemic neuronal damage.

"Our finding…sheds new light on the development of therapeutic agents against excitotoxic and acidotoxic neuronal damage," concluded the researchers. Also, they added, since such NMDARs and ASIC1a are involved in seizures and pain sensation, "a similar coupling between these two channels is likely to occur in these diseases as well."


'"/>

Source:Cell Press


Page: 1 2

Related biology news :

1. Molecular biology fills gaps in knowledge of bat evolution
2. Molecular machine may lead to new drugs to combat human diseases
3. Molecular Motors Cooperate In Moving Cellular Cargo, Study Shows
4. Molecular models advance the fight against malaria
5. Molecular fossils uncover link between viruses and the immune system
6. Molecular thermometers on skin cells detect heat and camphor
7. Molecular messengers perform a crucial role in the ability of injured nerve cells to heal themselves
8. Molecular steps involved in the creation of gene-silencing microRNAs identified
9. Molecular miners find pain relief drugs from the sea
10. Molecular mechanism of feather formation found
11. Molecular trigger for Huntingtons disease found
Post Your Comments:
(Date:12/16/2009)... of interactions. Today,s techniques, however, can only be ... cells. Since molecular concentrations are much higher in ... the kinetics of molecular reactions in living cells ... cellular reaction speed to be higher," confirms LMU ... approach showed that depending on the length ...
(Date:12/16/2009)... more than 4 billion years before humans showed up, ... more. That suggests they may have something to teach ... expert Prof. Eshel Ben-Jacob of the Raymond and Beverly ... study of bacteria, presents compelling evidence to suggest there ... automatically opt for the swine flu H1N1 shot. , ...
(Date:12/16/2009)... -- iQor, a global provider of business process outsourcing ... 100 Awards Top 100 IT project of 2009 ... first submission for iQor. ,, "We are honored to ... Vikas Kapoor, president and CEO of iQor. "TeQ21 is ... to work faster, smarter and with the added security ...
Breaking Biology News(10 mins):Looking for the heartbeat of cellular networks 2Bacteria wouldn't opt for a swine flu shot 2Bacteria wouldn't opt for a swine flu shot 3iQor Named to InfoWorld 100 List of Top IT Projects of 2009 2InfoLogix Receives Nasdaq Deficiency Letter 57862 1InfoLogix Receives Nasdaq Deficiency Letter 57862 2InfoLogix Receives Nasdaq Deficiency Letter 57862 3Senator Proposes Use of Internet Gambling Revenue to Help Fund Health Care Reform 57860 1Senator Proposes Use of Internet Gambling Revenue to Help Fund Health Care Reform 57860 2Ventus Medical Announces PROVENT 28R 29 Sleep Apnea Therapy Recognized by The Wall Street Journal 2009 Technology Innovation Awards 57857 1Ventus Medical Announces PROVENT 28R 29 Sleep Apnea Therapy Recognized by The Wall Street Journal 2009 Technology Innovation Awards 57857 2Ventus Medical Announces PROVENT 28R 29 Sleep Apnea Therapy Recognized by The Wall Street Journal 2009 Technology Innovation Awards 57857 3
... AIDS in Russia may be to treat HIV-infected drug users. ... suggests that treating injection drug users with antiretroviral medication will ... The study, which will appear in the December issue of the ... at the Veterans Affairs Palo Alto Health Care System and ...
... Dr. Erika Dyck has been unearthing some intriguing facts ... in Saskatchewan, Canada in the '50s and '60s. ... of medicine professor has found records of the psychiatrists' ... drug LSD, provided in a clinical, nurturing environment, can ...
... of Wisconsin School of Medicine and Public Health (SMPH) have ... development of drugs to destroy tumors caused by Epstein-Barr virus ... Proceedings of the National Academy of Sciences Online, identifies the ... to sustain EBV-related tumors. The researchers found that when they ...
Other Biology News:To slow AIDS in Russia, treat HIV-positive addicts, Stanford study says 2To slow AIDS in Russia, treat HIV-positive addicts, Stanford study says 3LSD treatment for alcoholism gets new look 2LSD treatment for alcoholism gets new look 3Clue found to Epstein-Barr virus' ability to form and sustain tumors 2
(Date:12/15/2009)... Thomson Reuters today announced ... first drug pipeline database to fully integrate detailed ... anticipated new content is being provided to all ... Thomson Pharma will offer drug related ... conferences, and other sources across all therapeutic areas. ...
(Date:12/15/2009)... of several innovative new programs to aid cash-strapped entrepreneurs ... climate. The first is aimed at entrepreneurs and ... a period of 6, 12, 18, or 24 months ... The second is aimed at more established businesses and ... 12 month period at discounted rates, and even the ...
(Date:12/14/2009)... Vermillion, Inc. (Pink Sheets: VRML), a molecular ... Ph.D. Chief Scientific Officer, Senior Vice President, ... be joining its board of directors upon ... "Bill brings more than 20 years research ... said Gail Page, Vermillion Executive Chairperson. ...
(Date:12/14/2009)... Joins with State Biotech Leaders to Develop ... and Development while Boosting Rhode Island,s Growing ... PROVIDENCE, R.I., Dec. 14 Several ... research, medicine and biotechnology gathered today at ... the importance of medical innovation in Rhode ...
Breaking Biology Technology:Thomson Reuters is First to Offer Fully Integrated Pipeline and Clinical Trials 2The Prinz Law Office Launches Innovative New Programs to Aid Cash-Strapped Entrepreneurs and Businesses 2Vermillion Announces Appointment of William C. Wallen, Ph.D. to Board of Directors 2Vermillion Announces Appointment of William C. Wallen, Ph.D. to Board of Directors 3Vermillion Announces Appointment of William C. Wallen, Ph.D. to Board of Directors 4Former Congressman Dick Gephardt Brings National Spotlight to Rhode Island with 'Best and Brightest Forum on Medical Innovation' 2Former Congressman Dick Gephardt Brings National Spotlight to Rhode Island with 'Best and Brightest Forum on Medical Innovation' 3Former Congressman Dick Gephardt Brings National Spotlight to Rhode Island with 'Best and Brightest Forum on Medical Innovation' 4
... status of interferon-stimulated signaling pathways , , ... Chao-Feng Zheng ,Stratagene , Stratagenes family of PathDetect ... systems, to better study the,activation of signal transduction pathways ... , or - g . The pISRE-Luc,cis-reporter plasmid ...
... LipoTAXI transfection reagent , Peter L. ... ,Clonetics Corporation, Walkersville, Maryland , LipoTAXI transfection ... offers,low cellular toxicity and high transfection efficiencies ... described for optimizing the amounts of LipoTAXI,transfection ...
... high-level expression in both,mammalian and bacterial cells ... ,Stratagene , Stratagene has developed the pdual expression ... both eukaryotic and prokaryotic,systems. The vector contains the ... immediate early gene for constitutive expression of cloned,DNA ...
Other Biology Technology:New Reporter Plasmids for Studying Interferon-Stimulated Signal Transduction,Pathways 2New Reporter Plasmids for Studying Interferon-Stimulated Signal Transduction,Pathways 3New Reporter Plasmids for Studying Interferon-Stimulated Signal Transduction,Pathways 4New Reporter Plasmids for Studying Interferon-Stimulated Signal Transduction,Pathways 5New Reporter Plasmids for Studying Interferon-Stimulated Signal Transduction,Pathways 6Low-Toxicity, Lipid-Mediated Transfection of Mammalian Cells 2Low-Toxicity, Lipid-Mediated Transfection of Mammalian Cells 3Low-Toxicity, Lipid-Mediated Transfection of Mammalian Cells 4Low-Toxicity, Lipid-Mediated Transfection of Mammalian Cells 5Mammalian and Bacterial Expression in One Vector 2Mammalian and Bacterial Expression in One Vector 3Mammalian and Bacterial Expression in One Vector 4Mammalian and Bacterial Expression in One Vector 5Mammalian and Bacterial Expression in One Vector 6
... provides excellent performance with isocratic IC ... and column heater all standard, this ... and stability. The vacuum degas option ... work. Operate in manual or automated ...
... The economical ICS-90 uses continuous chemical ... to give you fast, accurate determinations of ... ranges. Easy to operate, quick to equilibrate, ... the compact ICS-90 helps you achieve maximum ...
... AV-400 contains 400 unique human proteins ... slide. The proteins, all intracellular proteins ... are arrayed in quadruplicate for high-quality ... specific chip layout guarantee high validity ...
Sterile detoxified 10% bovine serum albumin (BSA) in Iscoves MDM. This BSA has been selected to support the optimal colony growth of human hematopoietic progenitor cells in methylcellulose-based medi...
Biology Products: