Navigation Links
Modified collagen could yield important medical applications

Altered protein could help deliver drugs and shape the growth of engineered tissueCollagen often pops up in beauty products and supermodel lips. But by mating collagen with a molecular hitchhiker, materials scientists at Johns Hopkins hope to create some important medical advances. The researchers have found a simple new way to modify collagen, paving the way for better infection-fighting bandages and a treatment to block the formation of unwanted scar tissue. In addition, tissue engineers may be able to use modified collagen in the lab to help control the formation of tiny new blood vessels that can be used to promote the integration of tissue implants in patients.

Michael (Seungju) Yu of the university's Whiting School of Engineering was scheduled to describe the new collagen modification process and its potential medical uses in an Aug. 30 presentation in Washington, D.C., at the 230th annual meeting of the American Chemical Society. His team also published a paper on the work earlier this year in the Journal of the American Chemical Society.

The research focuses on the human body's most common protein. Collagen promotes blood clotting and provides the sponge-like scaffold upon which cells build nerves, bones and skin. Because it is non-toxic, dissolves naturally over time and rarely triggers rejection, collagen is commonly used in cosmetics, drug delivery systems and biocompatible coatings.

Yu's goal is to change some of collagen's biochemical or mechanical properties to give it new medical applications. Traditionally, scientists have altered collagen by using intense heat or chemical reactions, techniques that may damage the protein or limit its safe use in humans. Yu's method, however, requires only physical mixing of collagen with even smaller molecules called collagen mimetic peptides.

"That's the beauty of this," said Yu, an assistant professor in the Department of Materials Science and Engineering. "If you want to attach the
'"/>

Source:Johns Hopkins University


Page: 1 2 3

Related biology news :

1. Genetically Modified Natural Killer Immune Cells Attack, Kill Leukemia Cells
2. Wisconsin scientists find a way to make human collagen in the lab
3. Protein discovery could unlock the secret to better TB treatment
4. Tiny particles could solve billion-dollar problem
5. First atlas of key brain genes could speed research on cancer, neurological diseases
6. Discovery of key proteins shape could lead to improved bacterial pneumonia vaccine
7. A comprehensive response to HIV could prevent 10 million AIDS deaths in Africa by 2020
8. How the environment could be damaging mens reproductive health
9. Dead zone area in Gulf could be increasing, researchers say
10. Growth in biomass could put US on road to energy independence
11. Nano-bumps could help repair clogged blood vessels
Post Your Comments:
*Name:
*Comment:
*Email:
TAG: Modified collagen could yield important medical applications

(Date:4/16/2014)... from the north-central U.S. and beyond will convene in ... science, expand on existing science, and explore the unique ... special emphasis on applied geology, paleontology, and mid-continent geology. ... Thursday by Dr. Kirk Johnson, Sant Director of the ... meeting is hosted by the University of Nebraska-Lincoln. Lincoln ...
(Date:4/16/2014)... Our ability to store memories improves during childhood, ... its connections with prefrontal and parietal cortices. New ... brain regions develop at this crucial time. Eventually, ... emerge in the transition into and during adolescence ... , Located deep in the middle of the ...
(Date:4/16/2014)... A research group composed of Dr. Martin Prechtl, Leo ... Department of Chemistry has discovered a new method of ... hydrogen from liquids is of particular interest when it ... project, entitled "Selective and mild hydrogen production using water ... Nature Communications . , Among other applications, the ...
Breaking Biology News(10 mins):Walking with mammoths and exploring mid-continental geology 2Walking with mammoths and exploring mid-continental geology 3Walking with mammoths and exploring mid-continental geology 4How kids' brain structures grow as memory develops 2
... NEW YORK (August 30, ... the Wildlife Conservation Society and Zoological Society of London have developed ... vanishing species over large landscapes. Called the "Wildlife Picture Index," (WPI) ... anything that lopes, waddles, or slinks past. These virtual photo ...
... lose weight or has osteoporosis: Scientists from Maine are on ... how we treat these two conditions. In a new research ... FASEB Journal , the researchers describe a newly discovered ... mass. Then they manipulated how much of this protein was ...
... the brilliant red of a male cardinal signals to females ... be true of cardinals living in urban areas, a new ... coloration of male northern cardinals (Cardinalis cardinalis) was less related ... it is for those in rural forests. In other words, ...
Cached Biology News:Photo album tells story of wildlife decline 2Scientists discover new protein that gets to the roots of obesity and osteoporosis 2Study: The bright red of cardinals means less in urban areas 2
(Date:1/15/2014)... 2014 The Microcompetition with Foreign DNA ... disease. One of these latent viruses is the Epstein ... rheumatoid arthritis (RA). Rheumatoid arthritis (RA) is a chronic ... by the theory, a study found that RA patients ... (1). , What is Microcompetition? , Dr. Hanan ...
(Date:1/15/2014)... Sunnyvale, CA (PRWEB) January 15, 2014 ... of high throughput research solutions, today announced that ... companies, has received delivery of Freeslate’s CM ... form screening. , Lupin, headquartered in Mumbai, ... quality, affordable generic and branded formulations and Active ...
(Date:1/14/2014)... (PRWEB) January 14, 2014 Date: Friday, ... p.m. , Location: Warrington Country Club, 1360 Almshouse Road, ... Foundation, the only national nonprofit organization solely dedicated to ... quality of life for those affected worldwide, will host ... Warrington Country Club in Warrington, Pa. , Each ...
(Date:1/14/2014)... , Jan. 14, 2014  3D Communications, a leading provider ... major scientific, regulatory, business, and media events in ... , today announced its former associate Virginia Cox , ... office. Virginia Cox re-joins ... Commissioner for the Office of External Affairs at the U.S. ...
Breaking Biology Technology:Study: Rheumatoid Arthritis (RA) Patients Have EBV; The CBCD Says this is Consistent with Microcompetition 2Study: Rheumatoid Arthritis (RA) Patients Have EBV; The CBCD Says this is Consistent with Microcompetition 3Lupin Selects Freeslate’s CM Protégé PharmD System to Accelerate Polymorph Screening for Drug Development 2Lupin Selects Freeslate’s CM Protégé PharmD System to Accelerate Polymorph Screening for Drug Development 3Hepatitis B Foundation to Host Annual Crystal Ball Gala 2Former FDA Associate Commissioner Returns To 3D Communications 2
... 14, 2011 DATATRAK International, Inc. (OTCQX: DATA), ... eClinical solutions for the clinical trials industry, today ... LTD to its Connect Partner Program.  The DATATRAK ... and its innovative processes using state-of-the-art clinical trial ...
... 2011 Reportlinker.com announces that a new ... catalogue: Global Immunochemicals Industry ... This report analyzes the worldwide markets ... following product segments – Catalog Antibodies, and ...
... 14, 2011 The global biotechnology industry delivered solid top- ... profitability for the second year in a row. ... scarce for the vast majority of firms in the sector, ... years of funding to support drug development. This has placed ...
Cached Biology Technology:Research Dynamics Becomes DATATRAK Connect Partner 2Research Dynamics Becomes DATATRAK Connect Partner 3Reportlinker Adds Global Immunochemicals Industry 2Reportlinker Adds Global Immunochemicals Industry 3Reportlinker Adds Global Immunochemicals Industry 4Reportlinker Adds Global Immunochemicals Industry 5Reportlinker Adds Global Immunochemicals Industry 6Reportlinker Adds Global Immunochemicals Industry 7Reportlinker Adds Global Immunochemicals Industry 8Reportlinker Adds Global Immunochemicals Industry 9Reportlinker Adds Global Immunochemicals Industry 10Despite Renewed Growth in 2010, Biotech Industry Faces R&D Challenges 2Despite Renewed Growth in 2010, Biotech Industry Faces R&D Challenges 3Despite Renewed Growth in 2010, Biotech Industry Faces R&D Challenges 4Despite Renewed Growth in 2010, Biotech Industry Faces R&D Challenges 5Despite Renewed Growth in 2010, Biotech Industry Faces R&D Challenges 6
... The Captivate magnetic separator ... be used in conjunction with ... C-21474, C-21476) or other magnetic ... most 96-well microplates. Cell Biology ...
RABBIT ANTI RAT AQUAPORIN 5...
MOUSE ANTI S. NEWPORT SALMONELLA HADAR...
Secure-Seal™ hybridization chamber gasket, eight chambers, 9 mm diameter, 0.8 mm deep *set of 20*...
Biology Products: