Navigation Links
Mitochondrial genes move to the nucleus -- but it's not for the sex

Why mitochondrial genes ditch their cushy haploid environs to take up residence in a large and chaotic nucleus has long stumped evolutionary biologists, but Indiana University Bloomington scientists report in this week's Science that they've uncovered an important clue in flowering plants.

"Plants that reproduce clonally or are capable of self-pollinating have transferred more genes from the mitochondrion to the nucleus," said graduate student Yaniv Brandvain, lead author of the paper.

That discovery, Brandvain explained, is unexpected. The most obvious benefit of being part of the nuclear genome is recombination, after all, but little recombination takes place in self-pollinating species. So what, exactly, might be luring mitochondrial genes to the nucleus?

"We're not quite sure why yet, but we've hypothesized that successful mitochondrial genes are pairing up with related nuclear genes," Brandvain said. "When you have two successful genes that depend on each other, it's best for them not to be in an environment in which they will recombine. It would be like breaking up a good musical duo."

Mitochondrial and nuclear genomes replicate separately, and a new and beneficial mutation in the mitochondrion could be separated from partner genes in the nucleus -- in the production of eggs or pollen, via meiosis. But the mating system determines whether or not this separation is permanent. With self-pollination, the components separated by meiosis are brought back together. In contrast, the components are further separated if they mix and match haphazardly during out-crossing.

Brandvain said the finding contradicts the expectation that mitochondrial genes migrate to the nucleus because of the evolutionary benefits conferred by sexual recombination. "The benefits of sex could have driven the transfer," he said. "There are powerful arguments out there for that. But that's just not what we saw."

Brandvain, fellow gr aduate student Michael Barker, and their advisor, IUB evolutionary biologist Michael J. Wade, examined papers that identified the sexual properties of plants that show evidence of mitochondrial-nuclear transfer. In all, the scientists collected data from plant species representing 170 genera.
'"/>

Source:Indiana University


Related biology news :

1. Mitochondrial DNA mutations play significant role in prostate cancer
2. Mitochondrial DNA sequencing tool updated
3. Newly-discovered class of genes determines ?and restricts ?stem cell fate
4. Inexpensive, mass-produced genes core of synthetic biology advances at UH
5. First atlas of key brain genes could speed research on cancer, neurological diseases
6. U-M scientists find genes that control growth of common skin cancer
7. Researchers find missing genes of ancient organism
8. Scientists document complex genomic events leading to the birth of new genes
9. Genrate: a generative model that finds and scores new genes and exons in genomic microarray data
10. Advances in the characterisation of the oyster mushroom genes
11. Researchers find new genes necessary to make embryo

Post Your Comments:
*Name:
*Comment:
*Email:


(Date:6/14/2017)... IBM ) is introducing several innovative partner startups at ... between startups and global businesses, taking place in ... startups will showcase the solutions they have built with IBM ... France is one of the most ... increase in the number of startups created between 2012 and ...
(Date:5/6/2017)... -- RAM Group , Singaporean based technology ... biometric authentication based on a novel  quantum-state ... perform biometric authentication. These new sensors are based on a ... Group and its partners. This sensor will have widespread ... security. Ram Group is a next generation sensor ...
(Date:4/17/2017)... , April 17, 2017 NXT-ID, Inc. (NASDAQ: ... announces the filing of its 2016 Annual Report on Form 10-K ... Commission. ... 10-K is available in the Investor Relations section of the Company,s ... the SEC,s website at http://www.sec.gov . 2016 Year ...
Breaking Biology News(10 mins):
(Date:10/11/2017)... Wayne. NJ (PRWEB) , ... October 11, 2017 , ... Personal eye wash is a ... rinse one eye at a time. So which eye do you rinse first if a ... you have Plum Duo Eye Wash with its unique dual eye piece. , ...
(Date:10/11/2017)... ... October 11, 2017 , ... ... today it will be hosting a Webinar titled, “Pathology is going digital. Is ... , on digital pathology adoption best practices and how Proscia improves lab economics ...
(Date:10/11/2017)... and LAGUNA HILLS, Calif. , ... of Cancer Research, London (ICR) and ... with SKY92, SkylineDx,s prognostic tool to risk-stratify patients with multiple ... as MUK nine . The University of ... is partly funded by Myeloma UK, and ICR will perform ...
(Date:10/11/2017)... ... October 11, 2017 , ... A new study published ... frozen and fresh in vitro fertilization (IVF) transfer cycles. The multi-center ... success. , After comparing the results from the fresh and frozen transfer cohorts, ...
Breaking Biology Technology: