Navigation Links
Misusing vitamin to foil drug test may be toxic; plus, it doesn't work

Taking excessive doses of a common vitamin in an attempt to defeat drug screening tests may send the user to the hospital—or worse.

Researchers from The Children's Hospital of Philadelphia and The University of Pennsylvania reported on two adults and two adolescents who suffered toxic side effects from taking large amounts of niacin, also known as vitamin B3, in mistaken attempts to foil urine drug tests.

Both adult patients suffered skin irritation, while both adolescents had potentially life-threatening reactions, including liver toxicity and hypoglycemia (low blood sugar), as well as nausea, vomiting and dizziness. One of the teens also had disrupted heart rhythms.

All four patients recovered after treatment in hospital emergency rooms for the adverse effects. The report appeared online in the Annals of Emergency Medicine.

"Testing urine for drugs is becoming increasingly common for job applicants," said study leader Manoj K. Mittal, M.D., a fellow in Emergency Medicine at The Children's Hospital of Philadelphia. "Because niacin is known to affect metabolic processes, there is a completely unfounded claim that it can rapidly clear the body of drugs such as cannabis and cocaine. However, niacin is toxic when taken in large amounts."

Niacin is easily available as an over-the-counter vitamin supplement. As a vitamin, the daily recommended intake is 15 milligrams, but niacin is used in much larger doses to treat vitamin deficiencies and other conditions. "People often assume niacin is completely safe," said Dr. Mittal. "As a water-soluble vitamin, it is easily excreted from the body. However, the body has its limits, and some of these patients took 300 times the daily recommended dose of niacin." Dr. Mittal added that there is a report in the medical literature of a patient who suffered liver failure, requiring a liver transplant, after taking excessive doses of niacin.

Many Internet sites promote the misconc eption that niacin can be used to pass urine drug screening tests, Dr. Mittal said. "We hope that our study will alert emergency medicine physicians and other health care providers to this hazardous practice."


'"/>

Source:Children's Hospital of Philadelphia


Related biology news :

1. Does vitamin C help prevent or treat the common cold? Maybe not, after all.
2. OHSU research shows vitamin C counteracts some negative impacts of smoking on unborn babies
3. Natural vitamin E tocotrienol reaches blood at protective levels
4. Poor athletic performance linked to vitamin deficiency
5. MIT biologists solve vitamin puzzle
6. Cocoa vitamin health benefits could outshine penicillin
7. Fat overrides effects of vitamin C
8. Heavy multivitamin use may be linked to advanced prostate cancer
9. To sea or not to sea: When it comes to salmon sex, size sometimes doesnt matter
10. What the eye doesnt see
11. Study finds evolution doesnt always favor bigger animals
Post Your Comments:
*Name:
*Comment:
*Email:


(Date:5/20/2016)... , May 20, 2016  VoiceIt is excited ... with VoicePass. By working together, VoiceIt ...  Because VoiceIt and VoicePass take slightly different approaches ... increases both security and usability. ... about this new partnership. "This marketing ...
(Date:5/16/2016)... --  EyeLock LLC , a market leader of iris-based ... IoT Center of Excellence in Austin, Texas ... embedded iris biometric applications. EyeLock,s iris authentication ... with unmatched biometric accuracy, making it the most proven ... platform uses video technology to deliver a fast and ...
(Date:5/12/2016)... May 12, 2016 WearablesResearch.com , a ... the overview results from the Q1 wave of its ... wave was consumers, receptivity to a program where they ... a health insurance company. "We were surprised ... says Michael LaColla , CEO of Troubadour Research, ...
Breaking Biology News(10 mins):
(Date:5/23/2016)... , May 23, 2016 Zimmer Biomet Holdings, ... healthcare, today announced that its Board of Directors has approved ... the second quarter of 2016. The cash ... about July 29, 2016 to stockholders of record as of ... of dividends are subject to approval of the Board of ...
(Date:5/23/2016)... Alto, CA (PRWEB) , ... May 23, 2016 ... ... and public interest organization focused on molecular nanotechnology, announced the winners for the ... of pioneer physicist Richard Feynman, are given in two categories, one for experiment ...
(Date:5/20/2016)... ... 20, 2016 , ... Korean researchers say Manumycin A triggers apoptosis, or natural ... to treat the disease. Surviving Mesothelioma has just posted an article on the new ... institutions based their mesothelioma study on the fact the Manumycin A, a derivative of ...
(Date:5/19/2016)... 19, 2016 There is no ... given the relentless pressures in pricing and lack in ... investors circle though - numerous opportunities are up for ... session, ActiveWallSt.com,s presents four names in this sector: Portola ... Inc. (NASDAQ: VTAE ), Anthera Pharmaceuticals Inc. ...
Breaking Biology Technology: