Navigation Links
Misusing vitamin to foil drug test may be toxic; plus, it doesn't work

Taking excessive doses of a common vitamin in an attempt to defeat drug screening tests may send the user to the hospital—or worse.

Researchers from The Children's Hospital of Philadelphia and The University of Pennsylvania reported on two adults and two adolescents who suffered toxic side effects from taking large amounts of niacin, also known as vitamin B3, in mistaken attempts to foil urine drug tests.

Both adult patients suffered skin irritation, while both adolescents had potentially life-threatening reactions, including liver toxicity and hypoglycemia (low blood sugar), as well as nausea, vomiting and dizziness. One of the teens also had disrupted heart rhythms.

All four patients recovered after treatment in hospital emergency rooms for the adverse effects. The report appeared online in the Annals of Emergency Medicine.

"Testing urine for drugs is becoming increasingly common for job applicants," said study leader Manoj K. Mittal, M.D., a fellow in Emergency Medicine at The Children's Hospital of Philadelphia. "Because niacin is known to affect metabolic processes, there is a completely unfounded claim that it can rapidly clear the body of drugs such as cannabis and cocaine. However, niacin is toxic when taken in large amounts."

Niacin is easily available as an over-the-counter vitamin supplement. As a vitamin, the daily recommended intake is 15 milligrams, but niacin is used in much larger doses to treat vitamin deficiencies and other conditions. "People often assume niacin is completely safe," said Dr. Mittal. "As a water-soluble vitamin, it is easily excreted from the body. However, the body has its limits, and some of these patients took 300 times the daily recommended dose of niacin." Dr. Mittal added that there is a report in the medical literature of a patient who suffered liver failure, requiring a liver transplant, after taking excessive doses of niacin.

Many Internet sites promote the misconc eption that niacin can be used to pass urine drug screening tests, Dr. Mittal said. "We hope that our study will alert emergency medicine physicians and other health care providers to this hazardous practice."


'"/>

Source:Children's Hospital of Philadelphia


Related biology news :

1. Does vitamin C help prevent or treat the common cold? Maybe not, after all.
2. OHSU research shows vitamin C counteracts some negative impacts of smoking on unborn babies
3. Natural vitamin E tocotrienol reaches blood at protective levels
4. Poor athletic performance linked to vitamin deficiency
5. MIT biologists solve vitamin puzzle
6. Cocoa vitamin health benefits could outshine penicillin
7. Fat overrides effects of vitamin C
8. Heavy multivitamin use may be linked to advanced prostate cancer
9. To sea or not to sea: When it comes to salmon sex, size sometimes doesnt matter
10. What the eye doesnt see
11. Study finds evolution doesnt always favor bigger animals
Post Your Comments:
*Name:
*Comment:
*Email:


(Date:3/11/2016)... 11, 2016 --> ... report "Image Recognition Market by Technology (Pattern Recognition), by ... by Deployment Type (On-Premises and Cloud), by Industry Vertical ... by MarketsandMarkets, the global market is expected to grow ... Billion by 2020, at a CAGR of 19.1%. ...
(Date:3/10/2016)... Pa. , March 10, 2016   Unisys Corporation ... Customs and Border Protection (CBP) is testing its biometric ... San Diego to help identify certain non-U.S. ... . The test, designed to help determine the efficiency ... environment, began in February and will run until May 2016. ...
(Date:3/9/2016)... Germany , March 9, 2016 ... country,s government identified that more than 23,000 public service ... or had been receiving their salary unlawfully.    ... African country,s government identified that more than 23,000 public ... name or had been receiving their salary unlawfully.    ...
Breaking Biology News(10 mins):
(Date:4/27/2016)... Md. and RESEARCH TRIANGLE PARK, ... Corporation (NASDAQ: UTHR ) announced today that ... Officer, of United Therapeutics will provide an overview and ... 41 st Annual Health Care Conference. ... 2016, at 10:00 a.m. Eastern Time, and can be ...
(Date:4/27/2016)... ... 2016 , ... NDA Partners Chairman Carl Peck, MD ... Consultant. Mr. Clark was formerly a Vice President with US Pharmacopeia, where ... monographs based on analytical methods. NDA Partners Expert Consultants are top tier ...
(Date:4/27/2016)... Manitoba (PRWEB) , ... April 27, 2016 , ... ... released for simultaneous preclinical PET (Positron Emission Tomography) and MRI (Magnetic Resonance Imaging) ... better understanding disease and testing novel treatments in small animal subjects. Simultaneous PET/MRI ...
(Date:4/27/2016)... ... April 27, 2016 , ... Global Stem Cells Group and ... Symposium as other research and development initiatives for potential stem cell protocol management for ... Stem Cells Group executives began meeting to establish a working agenda and foster initiatives ...
Breaking Biology Technology: