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MicroRNA tweaks protein that controls early heart development

r. Zhao analyzed all the known microRNA targets in worms and fruit flies to determine what they had in common, hoping to find clues to help predict unknown targets in mammals. He then used those criteria to search the entire mouse genome for potential microRNA targets.

"If this method of predicting targets turns out to be correct and specific, I think it will go a long way to opening the field more broadly, providing scientists who study microRNAs with an easier way to really figure out what they do," Dr. Srivastava said.

In addition to Dr. Srivastava and Dr. Zhao, UT Southwestern postdoctoral researcher in pediatrics Dr. Eva Samal also contributed to the research.


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Source:UT Southwestern Medical Center


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