Navigation Links
'Micro-boxes' of water used to study single molecules

Researchers at the National Institute of Standards and Technology (NIST) have demonstrated the use of water droplets as minuscule "boxes" for small numbers of biomolecules. The unusually simple containment method may enable easier experiments on single molecule dynamics and perhaps lead to the development of molecule-sorting devices that might be used for medical screening or biotechnology research. The work was reported in the July 3 issue of Applied Physics Letters.

The NIST team creates the boxes by briefly shaking a mixture of water, the biomolecules to be studied, and a fluorocarbon medium. Water droplets form in the oily fluorocarbon and naturally encapsulate one to several biomolecules. The researchers then watch through a microscope while using infrared lasers as "optical tweezers" to manipulate and combine the droplets (dubbed "hydrosomes") inside a tiny chamber on a slide.

A green laser is then used to excite the molecules in individual droplets, and the light emissions over several seconds are analyzed to count the molecules and observe other phenomena. The researchers use two sets of optical tweezers to move droplets together to fuse them and mix their contents (see accompanying video). The team demonstrated the technique by trapping and manipulating droplets encapsulating various molecules (including a delicate protein that survived the shaking process), detecting the fluorescence signal from dye and protein molecules, and observing the transfer of energy from one end of a specially treated DNA molecule to the other.

Water offers several advantages over other methods for containing single molecules, such as attaching them to surfaces or placing them inside liposomes (artificial cells). The water droplets can be held far from any surface that might interfere, can readily encapsulate biomolecules (which prefer being in water as opposed to the fluorocarbon medium), and can readily fuse together to mix molecules or rapidly change th
'"/>

Source:National Institute of Standards and Technology (NIST)


Page: 1 2

Related biology news :

1. Anti-bacterial additive widespread in U.S. waterways
2. Unprecedented water level rise in Somalia
3. Microbial fuel cell: High yield hydrogen source and wastewater cleaner
4. Survey finds silver contamination in North Pacific waters
5. Researchers discover underwater volcano
6. Too much water may be as dangerous as too little during long-distance athletic events
7. Radio-tracking associated with dramatic shift in water vole sex ratio
8. Major new UNC-based drinking water study suggests pregnancy fears may be overstated
9. Newly discovered genetic disease sheds light on bodys water balance
10. Beetle-inspired switch uses water for bonding
11. UNC computer, marine scientists collaborate to predict flow of toxic waters from Katrina
Post Your Comments:
*Name:
*Comment:
*Email:
TAG: Micro boxes water used study single molecules

(Date:7/31/2015)... China , 31. Juli 2015 Die 10. ... wird von BGI veranstaltet und findet vom 22. ... China , statt. Die ... Seit ihrem Start 2006 ist die ICG weltweit ... „omik" geworden. Sie ist eines der dynamischsten, enthusiastischsten ...
(Date:7/27/2015)... ANGELES , July 27, 2015   ... evidence- and experience-based clinical improvement solutions, today announced ... solution is now available on Android smartphones and ... inpatient and post-care organizations can use ZynxCarebook to ... same patient,s condition, streamline care transitions to other ...
(Date:7/21/2015)... 21, 2015 Passwords have proven futile ... the recent U.S. Office of Personnel Management breach. ... infosec conundrum, but developers and end-users are concerned ... this dilemma, Biometrics-as-a-Service provider HYPR Corp. announced today ... for third party integration. A ...
Breaking Biology News(10 mins):Die 10. internationale Konferenz zu Genomik (ICG-10) beginnt im Oktober 2Die 10. internationale Konferenz zu Genomik (ICG-10) beginnt im Oktober 3Zynx Health Adds Android Device Support to ZynxCarebook Solution 2Zynx Health Adds Android Device Support to ZynxCarebook Solution 3HYPR Corp. Launches Industry First Biometric Tokenization Platform 2HYPR Corp. Launches Industry First Biometric Tokenization Platform 3HYPR Corp. Launches Industry First Biometric Tokenization Platform 4
... Can the hold that Intelligent Design theorists have in ... a leading American evolutionist, makes the case for Darwin ... Reporting from the front lines of America's struggle over ... (University College London) on 16th November. , In his ...
... inoculate everyone in the United States could be grown ... plants, a University of Central Florida molecular biologist has ... UCF professor Henry Daniell's laboratory through the genetic engineering ... later by National Institutes of Health researchers. The results ...
... special green-algae gene into neurons of the tiny, ... to elicit specific behavioral responses by simply illuminating ... way for better understanding of how neurons communicate ... behavior in intact, living organisms. Generally speaking, detailed ...
Cached Biology News:'Creationism is not science' ?making the case for Darwin at UCL 2Effective, safe anthrax vaccine can be grown in tobacco plants 2Effective, safe anthrax vaccine can be grown in tobacco plants 3Algal protein in worm neurons allows remote control of behavior by light 2
(Date:8/5/2015)... , August 5, 2015 ... size is expected to reach USD 6.24 billion ... Grand View Research, Inc. The Increasing demand for ... are expected to drive the cell line development ... (Logo: http://photos.prnewswire.com/prnh/20150105/723757) , Increasing prevalence of ...
(Date:8/5/2015)... ... August 05, 2015 , ... ... and assessment of more organotypic 3D cell culture models, announced today that its ... (ULA) Plates are now available for purchase exclusively through PerkinElmer.     , InSphero ...
(Date:8/4/2015)... ... 04, 2015 , ... Graphite Metallizing Corporation, the manufacturer of ... appointment of Dennis Rawle as European Director of Sales. Rawle has over 25 ... General Manager and Technical Sales Manager for pump products at Exalto UK. Rawle ...
(Date:8/4/2015)... , Aug. 4, 2015  Blueprint Medicines (NASDAQ: ... selective kinase drugs for genomically defined diseases, today announced ... present a company overview at the 2015 Wedbush PacGrow ... p.m. EDT. A live webcast of the ... of the Blueprint Medicines website at www.blueprintmedicines.com . ...
Breaking Biology Technology:Cell Line Development Market To Reach $6.24 Billion By 2022: Grand View Research, Inc. 2Cell Line Development Market To Reach $6.24 Billion By 2022: Grand View Research, Inc. 3Cell Line Development Market To Reach $6.24 Billion By 2022: Grand View Research, Inc. 4Cell Line Development Market To Reach $6.24 Billion By 2022: Grand View Research, Inc. 5InSphero Expands Global Availability of its Patented 3D Cell Culture Platforms 2InSphero Expands Global Availability of its Patented 3D Cell Culture Platforms 3Dennis Rawle Joins Graphite Metallizing Corporation 2
... MINNEAPOLIS, May 9 ATS Medical, Inc. (Nasdaq:,ATSI), ... announced that it will participate at the Rodman ... Le Meridien Beach Plaza,Hotel in Monte Carlo on ... of ATS Medical, will present at 9:20 a.m. ...
... Inc. (OTC,Bulletin Board: PLMO) announced today that it ... taking its total holdings to 61% in this ... for pulmonary,related medical conditions., Pulmo BioTech CEO ... technology, developed and owned by PulmoScience, will dominate ...
... Pharmaceuticals today,announced that Scott Jackson has been appointed ... 2007 as Head of Commercial,Development., "We are ... He brings more than 20,years of pharmaceutical experience, ... oncology," said Dr. Joseph Mollica,Chairman of Celator,s Board ...
Cached Biology Technology:ATS Medical to Participate at the Rodman & Renshaw 5th Annual Global Healthcare Conference 2Pulmo BioTech Announces an Increase in its Stake in PulmoScience 2Pulmo BioTech Announces an Increase in its Stake in PulmoScience 3Celator(R) Pharmaceuticals Announces Appointment of Scott Jackson as CEO 2
SHEEP ANTI DEHYDROEPIANDROSTERONE...
... N.C. Price (1996) • This ... protein chemistry and the purification ... Data on the following procedures ... determination, amino acid analysis and ...
The Protein Kinase Factsbooks (2 Volume Set)...
... Silver Staining Kit, 1. Select from ... and peptides on denaturing, native, and ... reproducibility with precast gels, buffer strips, ... to that of radioisotopes with ready-to-use ...
Biology Products: