Navigation Links
Metal homeostasis research in plants will lead to nutrient-rich food and higher yielding crops

Deficiencies of micronutrients such as Iron and Zinc commonly limit plant growth and crop yields. Dartmouth Professor Mary Lou Guerinot is conducting research to better understand the mechanisms of micronutrient uptake, distribution and regulation.

Guerinot's findings are making it feasible to engineer nutrient-rich plants better able to grow in soils now considered marginal and to increase crop biomass in soils now in cultivation. Guerinot presented her findings 2 p.m. today (Wednesday, August 7) at the Annual Meeting of the American Society of Plant Biologists (ASPB) in the Hynes Convention Center, Boston.

Most people rely on plants for their dietary source of micronutrients. Therefore, plants engineered to be better sources of essential elements would offer humans improved nutrition. For example, over three billion people worldwide suffer from Iron and/or Zinc deficiencies. Food consumption studies suggest that doubling the Iron in rice can increase the Iron intake of the poor by 50 percent. Rice is a staple food in many of the countries with widespread Iron deficiencies in human diets.

Guerinot's lab has previously identified the essential Iron transporter responsible for Iron uptake from the soil. This Iron transporter is IRT1. In addition to transporting iron, IRT1 can also transport Manganese, Zinc, Cobalt and Cadmium. Thus, any attempts to increase Iron uptake via IRT1 must consider the transport of unwanted substrates such as Cadmium.

Industrial, mining, and agricultural activities, particularly the excessive use of phosphate fertilizers, have led to high levels of Cadmium contamination at many locations worldwide. Utilizing DNA shuffling and heterologous expression in yeast, Guerinot and her colleagues isolated alleles of IRT1 that no longer facilitate the accumulation of Cadmium yet retain the crucial ability to transport Iron. When the engineered IRT1 alleles are expressed in plants that no longer express a wild t ype copy of IRT1, the engineered allele allows these plants to take up iron and renders them resistant to Cadmium. Transgenic seedlings have Cadmium levels similar to that of IRT1 loss of function plants, demonstrating that Cadmium transport through IRT1 has been eliminated. Furthermore, these plants have twice as much Iron as wild type plants when grown in the presence of Cadmium.

While the ability to quantify the amount of particular metals present in various plant tissues has proved very informative, Guerinot said she and her colleagues would also like to be able to see where the metals are distributed within various plant organs.

"We have used X-ray fluorescence microtomography to determine, in vivo, the spatial distribution of metals in Arabidopsis seed. Examination of various mutants is shedding light on which transporters influence the distribution of important nutrients such as Iron in the seed. Such information should aid the development of nutrient-rich seed, beneficially affecting human nutrition and health. This research should also lead to agronomic benefits such as increased seedling vigor, higher crop yields and resistance to disease," Guerinot said.


'"/>

Source:American Society of Plant Biologists


Related biology news :

1. Metal-containing compounds show promise as HIV weapon
2. Columbia research lifts major hurdle to gene therapy for cancer
3. U of M researcher examines newly emerging deadly disease
4. NYU researchers simulate molecular biological clock
5. First atlas of key brain genes could speed research on cancer, neurological diseases
6. New research questions basic tenet of neuron function
7. Vital step in cellular migration described by UCSD medical researchers
8. ASU researchers finds novel chemistry at work to provide parrots vibrant red colors
9. UCSD researchers maintain stem cells without contaminated animal feeder layers
10. Why do insects stop breathing? To avoid damage from too much oxygen, say researchers
11. New protein discovered by Hebrew University researchers
Post Your Comments:
*Name:
*Comment:
*Email:


(Date:2/1/2016)... 2016  Wocket® smart wallet ( www.wocketwallet.com ) announces the launch of ... Fatone . Las Vegas , where Joey appeared ... Las Vegas , where Joey appeared at the Wocket ... video ad was filmed at the Consumer Electronics Show (CES2016) in ... to meet and greet fans. --> ...
(Date:1/27/2016)... , Jan. 27, 2016  Rite Track, Inc. ... in West Chester, Ohio announced ... winning service staff, based in Austin, Texas ... and ability to provide modifications, installations and technical support ... , CEO of PLUS, commented, "PLUS has provided world ...
(Date:1/25/2016)... -- Glencoe Software, the world-leading supplier of image data management ... the data management solution OMERO Plus for the newly ... Photo - http://photos.prnewswire.com/prnh/20160125/325328LOGO ... Phenotypic analysis measures the characteristics and behavior of cells, ... such as health and disease, the presence or absence ...
Breaking Biology News(10 mins):
(Date:2/10/2016)... -- IsoRay, Inc. (NYSE MKT: ISR), a medical technology company ... for the treatment of prostate, brain, lung, head and ... for the second quarter and six months of fiscal ... --> --> Revenue was $1.19 ... ended December 31, 2015, a 12% increase compared to ...
(Date:2/10/2016)... ... February 10, 2016 , ... ... states, announced today the promotion of two long-standing principal investigators (PI) to the ... Medicine, Clinical Research and Development. , Dr. Laurence Chu, a Benchmark Research PI ...
(Date:2/10/2016)... Charlotte, NC (PRWEB) , ... February 10, 2016 ... ... highly anticipated expansion to their comprehensive training and support program, Sonalinkā„¢ remote monitoring. ... Sonablate® HIFU procedures performed on Friday, February 5th, connecting Dr. Samuel Peretsman to ...
(Date:2/10/2016)... ... February 10, 2016 , ... ... announced a new agreement with Singapore-based Global Stem Cells Network (GSCN) and its ... Thailand and Singapore in the latest adipose and bone marrow therapies. , ...
Breaking Biology Technology: