Navigation Links
Memory loss affects more of the brain than previously thought

Memory loss associated with early Alzheimer's disease (AD) may be linked to altered activity in several areas of the brain, according to a study in the July issue of Radiology.

For the first time, researchers at Duke University Medical Center in Durham, N.C., used a special, high-field- strength, functional magnetic resonance imaging (fMRI) scanner to study the brain activity of people with amnestic mild cognitive impairment (MCI), a precursor to AD, and found altered functionality in both the frontal and temporal lobes of the brain. Previous studies looking at structural changes alone have shown evidence that brain atrophy in the earliest stages of AD tends to be restricted to the temporal lobe, a region critical to long-term memory formation.

"Involvement of both the frontal and temporal lobes in the earliest stages of AD suggests the possibility of a breakdown in the communication pathway between these two regions, which house short-term and long-term memory, respectively," said lead author Jeffrey R. Petrella, M.D., associate professor of radiology and director of Alzheimer's Disease Imaging Research Laboratory at Duke. "So in many ways the AD brain may be like a computer that is having problems with both its temporary files and its hard-drive files."

MCI affects an estimated 15 percent of the elderly population in the United States. Ten to 15 percent of people with MCI develop AD every year compared to one percent of the normal elderly population. Amnestic MCI is characterized by mild memory impairment and is often confused with ordinary age-related forgetfulness.

The researchers used 4-Tesla fMRI, which has a very strong magnetic field, to observe the brain activity of 20 elderly patients with amnestic MCI and 20 age-matched controls with no memory impairment during a memory task that tested memory formation and retrieval.

"It's like doing a treadmill test for heart patients, except this test puts your brain on a treadmi
'"/>

Source:Radiological Society of North America


Page: 1 2

Related biology news :

1. Researchers Uncover Key Step In Manufacture of Memory Protein
2. Nanogen Issued Patent for Electronic Microarray With Memory
3. Cytoplasm affects the number of vertebrae in carp-goldfish clones
4. Clam embryo study shows pollutant mixture adversely affects nerve cell development
5. Road salt affects mitigation wetlands
6. Exercise training in ordinary people affects the activity of 500 genes
7. Enzyme affects hypertension by controlling salt levels in body
8. Tropical Deforestation affects rainfall in the U.S. and around the globe
9. New study examines how sense of smell affects mating and aggression in mice
10. Gene variation affects tamoxifens benefit for breast cancer
11. New discovery: Molecular variation in one gene affects the growth of natural populations
Post Your Comments:
*Name:
*Comment:
*Email:
TAG: Memory loss affects more the brain than previously thought

(Date:7/11/2014)... A new report from the Wildlife Conservation Society ... only help economically valuable species such as lobster, ... also help re-colonize nearby reef areas. , The ... a systematic review of research literature from no-take ... by Dr. Craig Dahlgren, a recognized expert in ...
(Date:7/11/2014)... 11, 2014--Researchers at the Department of Energy,s Oak ... awards, presented by R&D Magazine in recognition of ... awards recognize the tremendous value of our National ... and development at the National Labs continues to ... pursue the scientific and technological innovations necessary to ...
(Date:7/11/2014)... in eastern New South Wales, Australia when NASA,s Aqua ... UTC on July 11 (12:35 p.m. local time/11:35 p.m. ... New South Wales (NSW), the Moderate Resolution Imaging Spectroradiometer ... region and spotted smoke (light brown) from various fires. ... outlined in red. , The New South Wales, Australia ...
Breaking Biology News(10 mins):Belize's lobster, conch, and fish populations rebuild in no-take zones 2ORNL wins eight R&D 100s 2ORNL wins eight R&D 100s 3ORNL wins eight R&D 100s 4
... researchers have discovered that a recently identified protein critical ... keep its repairs accurate. , The protein, called ... proteins known as DNA polymerases that are vital for ... other DNA-repair proteins insure their accuracy with the help ...
... sheds light on the molecular mechanisms underlying axon growth ... a study published today in the open access journal ... UNC-69, required for proper locomotion . They show that ... to be involved in the trafficking of vesicles along ...
... Portabella and crimini mushrooms rank with carrots, green beans, ... antioxidants, Penn State researchers say. , Dr. N. Joy ... at Penn State, measured the activity of two antioxidants, ... assay and HPLC instrumentation, as part of her dissertation ...
Cached Biology News:Unusual mechanism keeps repair protein accurate 2Unusual mechanism keeps repair protein accurate 3Newly identified protein complex sheds light on axon growth mechanism 2Mushrooms as good an antioxidant source as more colorful veggies 2
(Date:7/11/2014)... Cayenne Medical, Inc., a privately ... soft tissue reconstruction segment, announced the worldwide launch ... involving the shoulder and extremities. The SureLock System ... deployment method. The unique delivery eliminates manual tensioning ... or anchor displacement (also commonly know as anchor ...
(Date:7/10/2014)... 2014 Terascala, the industry leader in ... Swahn, a former vice president of product management for ... president of marketing. Terascala’s software when combined with leading ... the highest performance and most reliable solutions for processing ... Terascala’s channel expansion and broaden its product portfolio. His ...
(Date:7/10/2014)... CA (PRWEB) July 10, 2014 Senior ... institutions and professional associations, addressed the challenges of “Reducing ... Medical Device Industries” through strategic sourcing. Describing the partnership ... with the Supply Chain Management Institute ( SCMI) ... event on June 24 at the Kroc Institute of ...
(Date:7/10/2014)... , July 10, 2014 Research and ... of the "International Photonic Integrated Circuit (Monolithic ... to 2019" report to their offering. ... The concept of photonic integration traces its roots ... The promise of photonic integration went unexplored and ...
Breaking Biology Technology:Cayenne Medical Launches SureLock™ All-Suture Anchor System for Shoulder and Extremity Surgery 2Cayenne Medical Launches SureLock™ All-Suture Anchor System for Shoulder and Extremity Surgery 3Terascala Expands Executive Team 2Terascala Expands Executive Team 3Biotech & Biopharm Supply Chain Management Executives Launch BSMA in San Diego 2Biotech & Biopharm Supply Chain Management Executives Launch BSMA in San Diego 3Biotech & Biopharm Supply Chain Management Executives Launch BSMA in San Diego 4International Photonic Integrated Circuit (Monolithic Integration, Hybrid Integration, Module Integration) Market - Forecasts to 2019 2
... body of an ordinary family car consists of 193 different ... car has been carefully selected and optimised. It is important, ... because of the fuel consumption, whereas other parts of the ... passengers in a collision. Super strong nanostructured metals ...
... 21, 2011 ViroPharma Incorporated,s (Nasdaq: VPHM ) ... released on Thursday, July 28, 2011 before the open of ... a conference call and live audio webcast at 9:00 a.m. ... ViroPharma management will discuss the 2011 second quarter financial results ...
... Inc. (OTC/BB: GNBP), a biotechnology company developing targeted cancer ... Merrill A. McPeak to its Board of Directors.  General ... Force and was USAF chief of staff from 1990 ... 7 members, including 5 independent directors. "General ...
Cached Biology Technology:A new discovery paves the way for using super strong nanostructured metals in cars 2A new discovery paves the way for using super strong nanostructured metals in cars 3ViroPharma to Release 2011 Second Quarter Financial Results on July 28, 2011 2Genesis Biopharma Names Former Member of the Joint Chiefs of Staff General Merrill McPeak to Board of Directors 2
... scientists developed the Easy-Titer Human IgM Assay ... simple, sensitive, and easy-to-perform assay for Human ... ELISA. This kit incorporates a simple mix-and-read ... IgM concentration from 15-500 ng/ml in approximately ...
... clarification reagent; Ideal for clarifying many ... proteins, nucleic acids, & proteoglycans; Contains ... improves downstream processing; Utilizes a reagent ... supplied as a suspension in saline; ...
A simple, sensitive and reliable method for determining free sulfhydryl content in peptides, protein...
... true benchtop incubator-shaker, has the smallest footprint of ... of 540 x 680 mm (W x D) ... x 505 x 510mm). Available in 25 mm ... ideal for shaking applications requiring controlled speed and ...
Biology Products: